Role of Nanotechnology in the Management of Rheumatoid Arthritis

  • Faheem Mustafa University of Management and Technology
  • Ramsha Ajmal University of Management and Technology
  • Hafsa Salam University of Management and Technology
  • Rabiatul Adawiyah Binti Umar Universiti Sultan Zainal Abidin
  • Che Suhaili Binti Che Taha Universiti Sultan Zainal Abidin
  • Wan Rohani Binti Wan Taib Universiti Sultan Zainal Abidin
  • Shivani Chopra Saveetha University
  • Hitesh Chopra Chitkara College of Pharmacy, Chitkara University, Punjab, India
Keywords: Arthritis, rheumatoid, Autoimmune diseases, Nanotechnology, Nanoparticles, Drug delivery systems, Pharmaceutical preparations, Inflammation, Joints

Abstract


Rheumatoid arthritis (RA) is a debilitating autoimmune disease characterised by chronic inflammation of synovial joints, resulting in pain, stiffness and potential joint and bone damage. Left untreated, RA significantly impacts daily life and may lead to severe disability or death. Early diagnosis is critical to curbing disease progression and reducing inflammation and joint damage. Traditional drug therapies, although effective, often pose severe side effects, prompting interest in alternative and complementary approaches. Nanotechnology, particularly nanoparticles, has emerged as a transformative tool in RA management, offering enhanced drug delivery, improved diagnostic precision and reduced systemic side effects. This review explores the multifaceted role of nanotechnology in RA diagnosis and treatment, emphasising the synergistic potential of nanomedicine and natural compounds. Existing knowledge gaps and future research directions in leveraging nanotechnology for RA treatment are also discussed.    

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Published
2025/08/29
Section
Review article