Serotonin Syndrome: A Clinical Case Report

  • Mohamed Alshmandi Tallaght University Hospital
  • Haider Ali Tariq Butt Department of Medicine, Midland Regional Hospital of Portlaoise, Portlaoise, Ireland.
  • Julia Kiernan Department of Emergency Medicine, Perth Children’s Hospital, Perth, Western Australia, Australia
DOI: https://doi.org/10.5937/scriptamed56-61265
Keywords: Serotonin syndrome, Autonomic nervous system diseases, Hyperthermia, Neuromuscular diseases, Tremor

Abstract


Serotonin syndrome is characterised by high levels of serotonin, a neurotransmitter, in the nervous system. A 36-year-old male was hospitalised due to generalised weakness, loss of appetite, jaundice, abdominal pain, recurrent fever and delirium. Diagnoses of serotonin syndrome, peptic ulcer disease and metabolic-associated fatty liver disease (MAFLD) were confirmed. Management required withdrawal of the causative agent and administration of intravenous fluid support and benzodiazepines to control agitation and neuromuscular symptoms. This case clearly demonstrates the critical importance of thorough history-taking, careful clinical examination and reassessment of provisional diagnoses when initial treatments prove ineffective.

 

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Published
2025/12/31
Issue
Vol. 56 No. 6 (2025): Nov-Dec
Section
Case report
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