Perioperative Dysbiosis: Rethinking the Anaesthetic Contribution to Postoperative Outcomes via the Human Microbiota

  • Atif Amin Baig International Medical School, Management and Science University
  • Aye Thandar Htun School of Medicine, Taylor's University
  • Phone Myint Htoo International Medical School, Management and Science University, Malaysia
  • Wana Hla Shwe Faculty of Medicine and Health Sciences, UCSI, Malaysia
  • Kyaw Zaw Win Faculty of Medicine, Quest International University, Malaysia
  • Shivani Chopra Saveetha University
  • Hitesh Chopra Chitkara University
DOI: https://doi.org/10.5937/scriptamed56-62322
Keywords: Dysbiosis, Microbiota, Anaesthetics, Postoperative complications

Abstract


The gut microbiome plays a crucial role in perioperative care. Surgical stress and anaesthesia disrupt the balance of intestinal flora, known as dysbiosis, which can affect gut health and metabolism. Pain relievers like morphine and certain anaesthetics contribute to this imbalance. Dysbiosis may also lead to memory loss and cognitive issues post-surgery. Future studies aim to use probiotics and beneficial substances to improve health and prevent cognitive decline.

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Published
2025/12/31
Issue
Vol. 56 No. 6 (2025): Nov-Dec
Section
Letter to the Editor
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