Rare Concomitant Myxoid and Cystic Degeneration of Uterine Leiomyoma - Case Report

  • Igor Samardjiski Ss. Cyril and Methodius University - Faculty of Medicine, Skopje
  • Gordana Petrushevska Institute of Pthological Anatomy, Skopje, N.Macedonia
  • Slagjana Simeonova Krstevska University Clinic of Obstetrics and Gynaesology, Skopje, N. Macedonia
  • Iva Paneva University Clinic of Obstetrics and Gynaesology, Skopje, N. Macedonia
  • Vesna Livrinova University Clinic of Obstetrics and Gynaesology, Skopje, N. Macedonia
  • Irena Todorovska University Clinic of Obstetrics and Gynaesology, Skopje, N. Macedonia
  • Maja Ilieva Pejkovska University Clinic of Obstetrics and Gynaesology, Skopje, N. Macedonia
  • Sasho Dimitrovski University Clinic of Obstetrics and Gynaesology, Skopje, N. Macedonia
  • Katerina Nikoloska University Clinic of Obstetrics and Gynaesology, Skopje, N. Macedonia
Keywords: Leiomyoma, Myxoid degeneration, Cystic degeneration, Ovarian tumour, Differential diagnosis

Abstract


The uterine leiomyomas are monoclonal tumours of myometrial smooth muscle cells that are oestrogen dependent. A 43-year-old patient was referred by her gynaecologist under a suspected diagnosis of ovarian tumour. She complained of prolonged and profuse, regular menstrual bleeding that leaded to anaemia. The ultrasound examination showed a complex tumour mass with dimensions 68 x 85 mm, with several cystic formations fulfilled with clear fluid, which protrudes from the posterior wall of the uterus. Therefore, the diagnosis of leiomyoma with a cystic degeneration was considered preoperatively. In the case of cystic degeneration of the myoma, the ultra- sound shows a combination of cystic and solid components with irregular shape and variable echogenicity. The ovarian malignancy should be ruled out in the presence of a large cystic mass with irregular septa and solid nodular parts filling the small pelvis. Ultrasound characteristics of degenerative myomas should always be considered, so as not to replace it with an ovarian mass, especially if it is subserosal and on the loop.

References

Stewart EA, Cookson CL, Gandolfo RA, Schulze-Rath R. Epidemiology of uterine fibroids: a systematic review. BJOG 2017 Sep;124(10):1501-12.

Ciavattini A, Di Giuseppe J, Stortoni P, Montik N, Giannubilo SR, Litta P, et al. Uterine fibroids: pathogenesis and interactions with endometrium and endomyometrial junction. Obstet Gynecol Int 2013;2013:173184. doi: 10.1155/2013/173184.

Anyanwu M, Gassama K, Kandeh M. Diagnostic dilemma of hyaline cystic degeneration of uterine fibroids. Obstet Gynecol Int J 2019;10(3):202-5.

Han SC, Kim MD, Jung DC, Lee M, Lee MS, Park SI, et al. Degeneration of leiomyoma in patients referred for uterine fibroid embolization: incidence, imaging features and clinical characteristics. Yonsei Med J 2013 Jan 1;54(1):215-9.

Rashid SQ, Chou YH, Tiu CM. Ultrasonography of uterine leiomyomas. J Med Ultrasound 2016;24(1):3-12.

Kaushik C, Prasad A, Singh Y, Baruah BP. Case series: Cystic degeneration in uterine leiomyomas. Indian J Radiol Imaging 2008 Feb;18(1):69–72.

Fogata ML, Jain KA. Degenerating cystic uterine fibroid mimics an ovarian cyst in a pregnant patient. J Ultrasound Med 2006 May;25(5):671-4.

Published
2021/09/30
Section
Case report