The Povezanost zasićenosti kiseonikom, odnosa neutrofila i limfocita i d-dimera sa kliničkim manifestacijama pacijenata sa COVID-19

  • Marwan Marwan Faculty of Medicine Mulawarman University; Pulmonology Division-Laboratory of Internal Medicine, Abdul Wahab Sjahranie General Hospital
  • Muhammad Rizqan Khalidi Faculty of Medicine Mulawarman University; Laboratory of Anesthesiology Abdul Wahab Sjahranie General Hospital
  • Siti Khotimah Laboratory of Biochemistry Faculty of Medicine Mulawarman University
  • Sri Wahyunie Laboratory of Clinical Pathology Faculty of Medicine Mulawarman University; Abdul Wahab Sjahranie General Hospital
  • Lili Pertiwi Kalalo Laboratory of Clinical Pathology Faculty of Medicine Mulawarman University; Abdul Wahab Sjahranie General Hospital
  • Fanny Gomarjoyo Mulawarman University
DOI: https://doi.org/10.5937/scriptamed52-34641

Sažetak


Background / Aim: Coronavirus 2019 (COVID-19) infection is caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). It has become an emergency condition for global public health. Oxygen saturation has important role for diagnosing the patient in the hospital. The neutrophil-lymphocyte ratio (NLR) is a marker for the viral inflammatory reaction to confirm the viral or bacterial infection. The D-dimer is also known as biomarker for severity and prognosis of COVID-19. The aim of the study was to investigate
the risk factors of mortality in COVID-19 patients based on oxygen saturation, neutrophil-lymphocyte ratio and D-dimer.

Methods: Data has been obtained from confirmed cases of COVID-19 in AbdulWahab Sjahranie Hospital from October until November 2020. They were collected and analysed with Chi-squared test by SPSS 22.0 software.
Results: There were 60 patients with SARS-CoV-2 infection in this study, 48 (80 %) patients survived and 12 (20 %) deceased. Peripheral oxygen saturation < 90 % had 13 (21.7 %) and ≥ 90 % had 47 (78.3 %) patients. There were 13 (21.7 %) patients with NLR value < 3.13 and ≥ 3.13 47 (78.3 %) patients. D-dimer value less than 0.5 had 9 (15 %) and ≥ 0.5 had 51 (85 %) patients. The results of statistical analysis have showed that there were relationship between oxygen saturation (p = 0.002) and survival rate of COVID patients.

Conclusion: According to the research that has been conducted, there was correlation between oxygen saturation and mortality of COVID-19 patient. It could be used as biomarker to improve the management of COVID-19 patients.

Biografije autora

Marwan Marwan, Faculty of Medicine Mulawarman University; Pulmonology Division-Laboratory of Internal Medicine, Abdul Wahab Sjahranie General Hospital

Faculty of Medicine Mulawarman University; Pulmonology Division-Laboratory of Internal Medicine, Abdul Wahab Sjahranie General Hospital

Muhammad Rizqan Khalidi, Faculty of Medicine Mulawarman University; Laboratory of Anesthesiology Abdul Wahab Sjahranie General Hospital

Faculty of Medicine Mulawarman University; Laboratory of Anesthesiology Abdul Wahab Sjahranie General Hospital

Siti Khotimah, Laboratory of Biochemistry Faculty of Medicine Mulawarman University

Laboratory of Biochemistry Faculty of Medicine Mulawarman University

Sri Wahyunie, Laboratory of Clinical Pathology Faculty of Medicine Mulawarman University; Abdul Wahab Sjahranie General Hospital

Laboratory of Clinical Pathology Faculty of Medicine Mulawarman University; Abdul Wahab Sjahranie General Hospital

Lili Pertiwi Kalalo, Laboratory of Clinical Pathology Faculty of Medicine Mulawarman University; Abdul Wahab Sjahranie General Hospital

Laboratory of Clinical Pathology Faculty of Medicine Mulawarman University; Abdul Wahab Sjahranie General Hospital

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Objavljeno
2021/12/31
Broj časopisa
Vol. 52 Br. 4 (2021): Q4/December
Rubrika
Originalni naučni članak
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