Istraživanje povezanosti između krvnog pritiska i kapilarnih parametara kožnog nabora nokta kod trudnica koje vježbaju i koje ne vježbaju

  • Vesna Ljubojević Department of Histology and Embryology, Faculty of Medicine, University of Banja Luka
  • Vlatka Bojanić Midwifery, Faculty of Medicine, University of Banja Luka; Pregnancy center “Radosnica”, Banja Luka, the Republic of Srpska, Bosnia and Herzegovina;
  • Tatjana Nožica-Radulović Department of Physical Medicine and Rehabilitation, Faculty of Medicine, University of Banja Luka; Institute for Physical Medicine and Rehabilitation „Dr Miroslav Zotović”, Banja Luka, the Republic of Srpska, Bosnia and Herzegovina
  • Dragica Draganović Department of Gynecology and Obstetrics, Faculty of Medicine, University of Banja Luka; University Clinical Center of Republic of Srpska Banja Luka, the Republic of Srpska, Bosnia and Herzegovina
  • Saša Skočić-Smoljanović
DOI: https://doi.org/10.5937/scriptamed53-38104
Ključne reči: prenatalne vježbe, trudnoća, krvni pritisak, kapilar kožnog nabora nokta, digitalna analiza slike

Sažetak


Uvod: U trudnoći sa povećanjem minutnog volumena se povećavaju vrednosti krvnog pritiska. Cilj rada bio je da se ispita uticaj prenatalnih vežbi na parametre cirkulacije i korelaciju između krvnog pritiska i kapilarnih parametara kožnog nabora nokta kod zdravih trudnica.

Metode: Krvni pritisak, oblik i dužina kapilara kožnog nabora nokta su utvrđeni kod 35 trudnica koje nisu vežbale i 35 trudnica koje su vežbale, na početku studije (između 20 i 32 nedelje trudnoće) i na kraju studije (28 - 40).

Rezultati: Povišenje krvnog pritiska je značajno niže kod trudnica koje su vežbale u odnosu na trudnice koje nisu vežbale. Posle osam nedelja, dužina kapilarnih petlji se povećala za 30 µm, a broj trudnica sa izraženim promenama oblika kapilarnih petlji se povećao, bez razlike između grupa. Kod trudnica koje ne vežbaju postojala je korelacija između promene dijastolnog krvnog pritiska i povećanja dužine kapilara (r=0,53, p=0,001). U eksperimentalnoj grupi nije utvrđena korelacija između promene krvnog pritiska i povećanja dužine kapilarnih petlji.

Zaključak: Prenatalna fizička aktivnost je pozitivno uticala na cirkulaciju trudnica. Kod trudnica u trećem tromesečju, posle osmonedeljnog praćenja, povećana je dužina kapilarnih petlji kožnog nabora nokta i prisustvo izraženih promena oblika kapilarnih petlji, bez razlike između trudnica koje vježbaju i onih koje ne vežbaju. Kod trudnica koje ne vežbaju, dužina kapilara se povećala sa povećanjem dijastolnog krvnog pritiska, dok korelacija nije utvrđena kod trudnica koje su vežbale.

Reference

1.    Thevissen K, Gyselaers W. Capillaroscopy in pregnancy. Expert Rev Med Devices 2017;14(12):961-7.

2.    Porcelli BA, Diveley E, Meyenburg K, Woolfolk C, Rosenbloom JI, Raghuraman N, et al. A new definition of gestational hypertension? New-onset blood pressures of 130 to 139/80 to 89 mm Hg after 20 weeks of gestation. Am J Obstet Gynecol 2020;223(3):442.e1-442.e7.  doi: 10.1016/j.ajog.2020.06.019.

3.    Nama V, Manyonda IT, Onwude J, Antonios TF. Structural capillary rarefaction and the onset of preeclampsia. Obstet Gynecol 2012;119:967–74.

4.    Mulder EG, de Haas S, Mohseni Z, Schartmann N, Abo Hasson F, Alsadah F, et al. Cardiac output and peripheral vascular resistance during normotensive and hypertensive pregnancy - a systematic review and meta-analysis. BJOG 2022;129(5):696-707.

5.    Purdy GM, James MA, Wakefield PK, Skow RJ, Van Diepen S, May LE, et al. Maternal cardioautonomic responses during and following exercise throughout pregnancy. Appl Physiol Nutr Metabol 2019;44(3):263-70.

6.    Poon LC, Shennan A, Hyett JA, Kapur A, Hadar E, Divakar H, et al. The International Federation of Gynecology and Obstetrics (FIGO) initiative on pre‐eclampsia: A pragmatic guide for first‐trimester screening and prevention. Int J Gynaecol Obstet 2019;145(Suppl 1):1–33.

7.    Hitti J, Sienas L, Walker S, Benedetti TJ, Easterling T. Contribution of hypertension to severe maternal morbidity. Am J Obstet Gynecol 2018;219(4):405.e1-405.e7. doi: 10.1016/j.ajog.2018.07.002.

8.    Draganovic D, Cancarevic-Djajic B, Jojic D, Ljubojevic V, Todorovic J . The possibility of clinical use for the oxidative stress marker in correlation with blood flow parameters in pregnancy-induced hypertension. Rev Rom Med Labor 2021;29(2):143-51.

9.    Boardman H, Lamata P, Lazdam M, Verburg A, Siepmann T, Upton R, et al. Variations in cardiovascular structure, function and geometry in midlife associated with a history of hypertensive pregnancy. Hypertension 2020;75(6):1542-50.

10.  Mishra A, Grover C, Singal A, Narang S, Das GK. Nailfold capillary changes in newly diagnosed hypertensive patients: An observational analytical study. Microvasc Res 2021 Jul;136:104173. doi: 10.1016/j.mvr.2021.104173.

11.  Haakstad LA, Edvardsen E, Bø K. Effect of regular exercise on blood pressure in normotensive pregnant women. A randomized controlled trial. Hypertens Pregnancy 2016;35(2):170-80.

12.  de Castro R, Antunes R, Mendes D, Szumilewicz A, Santos-Rocha R. Can group exercise programs improve health outcomes in pregnant women? An updated systematic review. Int J Environ Res Public Health 2022;19(8):4875. doi: 10.3390/ijerph19084875.

13.  Davenport MH, Ruchat SM, Poitras VJ, Garcia AJ, Gray CE, Barrowman N, et al. Prenatal exercise for the prevention of gestational diabetes mellitus and hypertensive disorders of pregnancy: a systematic review and meta-analysis. Br J Sports Med 2018;52(21):1367–75.

14.  Davenport MH, Skow RJ, Steinback CD. Maternal responses to aerobic exercise in pregnancy. Clin Obstet Gynecol 2016;59(3):541-51.

15.  ACOG Committee Opinion No. 650: Physical activity and exercise during pregnancy and the postpartum period. Obstet Gynecol 2015 Dec;126(6):e135-e142. doi: 10.1097/AOG.0000000000001214.

16.  Smith V, Beeckman S, Herrick AL, Decuman S, Deschepper E, De Keyser F. EULAR study group on microcirculation. An EULAR study group pilot study on reliability of simple capillaroscopic definitions to describe capillary morphology in rheumatic diseases. Rheumatology 2016;5(5):883-90.

17.  Etehad Tavakol M, Fatemi A, Karbalaie A, Emrani Z, Erlandsson BE. Nailfold capillaroscopy in rheumatic diseases: which parameters should be evaluated? BioMed Research Int 2015;2015:974530. doi: 10.1155/2015/974530.

18.  Arvanitaki A, Giannakoulas G, Triantafyllidou E, Feloukidis C, Boutou AK, Garyfallos A, et al. Peripheral microangiopathy in precapillary pulmonary hypertension: a nailfold video capillaroscopy prospective study. Respir Res 2021;22(1):1-9.

19.  Đukanović Đ, Gajić M, Škrbić R. Time-dependent and force-dependent vasoreactivity of isolated human umbilical arteries. Scr Med 2020;51(3):134-40.

20.  Rodríguez-Díaz L, Ruiz-Frutos C, Vázquez-Lara JM, Ramírez-Rodrigo J, Villaverde-Gutiérrez C, Torres-Luque G. Effectiveness of a physical activity programme based on the Pilates method in pregnancy and labour. Enferm Clín (English Edition) 2017;27(5):271-7.     

21.  Tian J, Xie Y, Li M, Oatts J, Han Y, Yang Y, et al. The relationship between nailfold microcirculation and retinal microcirculation in healthy subjects. Front Physiol 2020;11:880-9.

22.  Pacini G, Schenone C, Pogna A, Ferraiolo A, Ferrero S, Gustavino C, et al. Full longitudinal nailfold videocapillaroscopy analysis of microvascular changes during normal pregnancy. Microvasc Res 2022;141:104343. doi: 10.1016/j.mvr.2022.104343.

23.  Pizzorni C, Ferrari G, Schenone C, Hysa E, Carmisciano L, Gotelli E, et al. Capillaroscopic analysis of the microvascular status in mixed versus undifferentiated connective tissue disease. Microvasc Res 2022;142:104367. doi: 10.1016/j.mvr.2022.104367.

24.  Bojanić V, Ljubojević V, Nožica-Radulović T, Lazović M. Research on the influence of prenatal exercises on anthropometric and vascular parameters in pregnant women. Srp Arh Celok Lek 2022;150(5-6):330-5.

Objavljeno
2022/12/28
Broj časopisa
Vol. 53 Br. 4 (2022): Q4/December
Rubrika
Originalni naučni članak
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