Epidemiological Study in Admitted Patients With Ischaemic Heart Disease at a Tertiary Care Hospital in North-Western India

  • Arun Singh SMS Medical College & Attached Hospitals, Jaipur https://orcid.org/0009-0005-9821-0587
  • Dhirendra Kumar Mahawar SMS Medical College & Attached Hospitals, Jaipur https://orcid.org/0000-0002-0132-239X
  • Monica Jain SMS Medical College & Attached Hospitals, Jaipur
  • Rupa Kapadia SMS Medical College & Attached Hospitals, Jaipur
  • Jaya Dadhich SMS Medical College & Attached Hospitals, Jaipur

Sažetak


Background/Aim: Ischaemic heart disease (IHD) is a major cause of morbidity and the leading cause of mortality in either men or women globally. IHD incidence is more common in the elderly and there are multiple well-known risk factors for IHD. This study aimed to evaluate the epidemiological trend of IHD in North-Western India. This study also evaluated the risk factors of IHD and associated comorbidities.

Methods: A cross-sectional observational study for a period of 12 months was conducted in the Cardiology Department of the Tertiary Care Hospital, Jaipur, India. A total of 400 IHD patients were enrolled in this study. Statistical Package for Social Sciences (SPSS) version 20.0 software was used for statistical calculation.

Results: The most common age group was 61-80 years (Mean age was 57.8 ± 0.66) with men predominated (76.3 %). More patients (56 %) were from urban areas than rural areas (44 %). Among all the patients, 161 (40.3 %) patients were smokers and 42 (10.3 %) were alcoholics. Hypertension (34.8 %) followed by diabetes mellitus (17 %) and obesity (7.3 %) were found to be the predominant risk factors.

Conclusion: IHD was more common in elderly patients and in men. Heavy alcohol consumption and smoking were potential risk factors for the development of IHD. Hypertension, diabetes mellitus and obesity also significantly contributed to occurrence of IHD. The burden of the IHD can be reduced by the limiting alcohol consumption, smoking cessation and adaptation of healthy lifestyle.

Biografije autora

Arun Singh, SMS Medical College & Attached Hospitals, Jaipur

Senior Resident, Department of Pharmacology

Dhirendra Kumar Mahawar, SMS Medical College & Attached Hospitals, Jaipur

Assistant Professor, Department of Pharmacology

Monica Jain, SMS Medical College & Attached Hospitals, Jaipur

Senior Professor, Department of Pharmacology

Rupa Kapadia, SMS Medical College & Attached Hospitals, Jaipur

Senior Professor, Department of Pharmacology

Jaya Dadhich, SMS Medical College & Attached Hospitals, Jaipur

Senior Demonstrator

Reference

1.    Institute of Medicine (US) Committee on Social Security Cardiovascular Disability Criteria. Cardiovascular disability: updating the social security listings. Washington (DC): National Academies Press (US); 2010. DOI: 10.17226/12940.

2.    Coronary Heart Disease [Internet]. [Cited: 8-Feb-2023]. Available from: https://www.bhf.org.uk/informationsupport/conditions/coronary-heart-disease.

3.    PIB. NPCDCS: Managing non-communicable diseases. Press Information Bureau GOI. [Internet]. [Cited: 15-Feb-2020]. Available from: http://pib.nib.in/newsite/efeatures.aspx?relid =76249.

4.    Gupta R, Gupta VP, Sarna M, Bhatnagar S, Thanvi J, Sharma V, et al. Prevalence of coronary heart disease and risk factors in an urban Indian population: Jaipur heart watch-2. Indian Heart J 2002;54(1):59-66.

5.    World Health Organisation. Miscoding and misclassification of ischaemic heart disease mortality. World Health Organisation; 2001. [Internet]. [Cited: 8-Feb-2023]. Available from: http://www.who.int/healthinfo/paper12.pdf.

6.    Gupta R, Joshi P, Mohan V, Reddy KS, Yusuf S. Epidemiology and causation of coronary heart disease and stroke in India. Heart 2008;94(1):16-26.

7.    Kutty VR, Balakrishnan KG, Jayasree AK, Thomas J. Prevalence of coronary heart disease in the rural population of Thiruvananthapuram district, Kerala, India. Int J Cardiol 1993;39(1):59-70.

8.    Jajoo UN, Kalantri SP, Gupta OP, Jain AP, Gupta K. The prevalence of coronary heart disease in rural population from central India. J Assoc Physicians India 1988;36(12):689-93.

9.    Wander GS, Khurana SB, Gulati R, Sachar RK, Gupta RK, Khurana S, et al. Epidemiology of coronary heart disease in a rural Punjab population–prevalence and correlation with various risk factors. Indian Heart J 1994;46(6):319-23.

10.  Prabhakaran D, Jeemon P, Roy A. Cardiovascular diseases in India: current epidemiology and future directions. Circulation 2016 Apr 19;133(16):1605-20.

11.  Hijazi W, Jolly SS, Budaj A, Beręsewicz A, Undas A. Ischemic heart disease (IHD). McMaster textbook of internal medicine. Kraków: Medycyna Praktyczna. [Cited: 9-Feb-2023]. Available from: https://empendium.com/mcmtextbook-sae/chapter/B78.II.2.5.?rfmcm.

12.  Brown JC, Gerhardt TE, Kwon E. Risk factors for coronary artery disease. 2023 Jan 23. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. [Cited: 10-Feb-2023].  Available from:  https://www.ncbi.nlm.nih.gov/books/NBK554410/.

13.  Mahmood SS, Levy D, Vasan RS, Wang TJ. The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective. Lancet 2014 Mar 15;383(9921):999-1008.

14.  Alexander RW. Hypertension and the pathogenesis of atherosclerosis. Oxidative stress and the mediation of arterial inflammatory response: a new perspective. Hypertension 1995;25(2):155-61.

15.  Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, et al. American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics--2015 update: a report from the American Heart Association. Circulation 2015;131(4):e29-322.

16.  Dababneh E, Goldstein S. Chronic Ischemic Heart Disease Selection of Treatment Modality. 2023 Feb 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. [Cited: 10-Feb-2023]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507703/.

17.  Committee on the Analysis of Cancer Risks in Populations near Nuclear Facilities-Phase I; Nuclear and Radiation Studies Board; Division on Earth and Life Studies; National Research Council. Analysis of cancer risks in populations near nuclear facilities: phase I. Washington (DC): National Academies Press (US); 2012 Mar 29. 4, Epidemiologic Studies. [Cited: 10-Feb-2023]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK201995/. style="mso-spacerun: yes;"> 

18.  Sawant MP, Padwal SL, Jadhav RR, Pise HN, Shinde R. Study of drug prescription pattern in ischemic heart disease patients. Int J Basic Clin Pharmacol 2019;8:1473. DOI: https://doi.org/10.18203/2319-2003.ijbcp20192644.>

19.  Saju D, Joy C, Moorthy MA, Wilson B, Antony J, Singaravel S, et al. Prescription pattern and drug utilization analysis in patients with acute coronary syndrome. Indian J Pharm Pract 2020;13(1):73-9.

20.  Swathi M, Akhilendran R, Hima M, Fahida F, Veena V, Pradeep P. Analysis of drug prescribing pattern and sociodemographic background in patients with coronary artery disease in a tertiary care hospital. EJPMR 2016;3(11):352-8.

21.  Panchaksharimath P, Praveen AN, Manjunath R. A cross-sectional study to evaluate age and gender related differences in drug utilization in ischemic heart disease at a tertiary care hospital. Biomed Pharmacol J 2018;11(4):1967-74.

22.  Gaur A, Deepak K, Rathore MS, Sharma A, Haque I. Drug utilization evaluation of coronary artery disease in a tertiary care hospital in Punjab. RJPT 2019;12(1):149-55.

23.  Shankar R, Partha P, Shenoy N. Prescribing patterns of drugs among patients admitted with cardiovascular disorders in the internal medicine ward: prescribing patterns in inpatients. Internet J Pharmacol 2001;1:1-5.

24.  Hbejan K. Smoking effect on ischemic heart disease in young patients. Heart views 2011;12(1):1-6.

25.  Goldberg RJ. Coronary Heart Disease: epidemiology and risk factors. In: Ockene IS, Ockene JK. Prevention of coronary heart disease. Boston, Mass: Little Brown & Co Inc; 1992. pp. 3-40.

26.  Gregory AB, Lester KK, Gregory DM, Twells LK, Midodzi WK, Pearce NJ, et al. The relationship between body mass index and the severity of coronary artery disease in patients referred for coronary angiography. Cardiol Res Pract 2017;2017:5481671. doi: 10.1155/2017/5481671.

27.  Leon BM, Maddox TM. Diabetes and cardiovascular disease: Epidemiology, biological mechanisms, treatment recommendations and future research. World J Diabetes 2015; 6(13):1246-58.

Objavljeno
2023/09/20
Rubrika
Originalni naučni članak