Twelve Decades of Using Radium in the Treatment of Deeper Localised Cancers

  • Goran Kolarević International Medical CentersBanja Luka https://orcid.org/0000-0003-2610-5911
  • Oliver Arsovski Centar za radijacijsku terapiju, Me]unarodni medicinski centri, Affidea, Banja Luka, Republika Srpska, Bosna i Hercegovina
  • Branko Predojević Prirodno-matematički fakultet, Univerzitet u Banjoj Luci, Banja Luka, Republika Srpska, Bosna i Hercegovina
Ključne reči: Radioaktivnost, Radijum, Alexander Bell, Brahiterapija, Jonizujuća radijacija

Sažetak


The end of the 19th and the beginning of the 20th century marked a period of fundamental discoveries in the physics of ionising radiation (X radiation and radioactivity). Isolating radium, a highly radioactive element, immediately opened the way to its application for medical therapeutic purposes. It turned out that the sources of ionising radiation are very effective for changes localised on the skin and at small depths under the skin but not for lesions at greater depths. Interestingly, the inventor of the modern telephone, Alexander Graham Bell, was the first to come up with the idea of placing radium sources in glass tubes and placing them directly in the pathologically changed tissues of the patients to be treated (at greater depths). That period marked the beginning of a highly successful era in radium therapy, involving the use of capsules and needles filled with radium, which eventually led to the development of modern brachytherapy. Unfortunately, for several decades people believed in the universally therapeutic properties of radium, so that (fortunately in smaller quantities) it was added to water, food, hygiene products, etc.

Biografija autora

Goran Kolarević, International Medical CentersBanja Luka

Center for Radiotherapy

PhD, cheaf medical physicist

Reference

Becquerel H. Sur les radiations mises par phosphorescence. Comptes rendus des sances de l'Acadmie des Sciences Paris 1896;122:420-1. French.

Sklodowska Curie M. Rayons emis par les composesde l uranium et du thorium. Comptes Rendus, Paris 1898;126:1101-3. French.

Schmidt G. Ueber die von den Thorverbindungen und einigen anderen Substanzen ausgehende Strahlung. Annalen der Physik und Chemie, Berlin 1898;301(5):141-51. German.

Curie P, Curie M. Sur une substance nouvelle radio-active, contenue dans la pechblende. Comptes Rendus, Paris 1989;127:175-8. French.

Curie P, Curie M, Bemont G. Sur une nomelle substance fortement radio-active, contenue dans la pechblende. Comptes Rendus, Paris 1989;127:1215-7. French.

Supek I. [History of physics]. Zagreb: Skolska knjiga, 1980. Croatian.

Curie M, Debierne A. Sur le polonium. Le radium, Paris 1910;7(2):38-40.

Kemikler G. History of brachytherapy. Turk J Oncol 2019;34(1):1–10.

Zimmermann R. Nuclear Medicine: Radioactivity for Diagnosis and Therapy. Orsay 2017.

Mazeron JJ, Gerbaulet A. The centenary of discovery of radium. Radiother Oncol 1998;49(3):205-16.

Osborne H. Biographical Memoir of Alexander Graham Bell 1847-1922. National Academy of Sciences of the united states of America 1943; Volume XXIII-first memoir.

Glicksman A. Radiobiologic basis of brachytherapy. Seminars in oncology. Nursing 1987;3(1):3-6.

Bell AG. Radium and Cancer (Letter to Dr. Z. T. Sowers). Science 1903:155-6.

Podgorsak E. Radiation physics for medical physicists. Berlin: Springer, 2010.

Dutreix J, Tubiana M, Pierquin B. The hazy dawn of brachytherapy. Radiother Oncol 1998;49(3):223-32.

Catalogue of Radium and accessory equipment for modern radium therapy. Toronto: X-ray and radium industries limited, 1940.

Reed AB. The history of radiation use in medicine. J Vasc Surg 2011;53(1):3S-5S.

Objavljeno
2023/12/21
Rubrika
Članak iz istorije medicine