Ethnopharmacology, Chemical Composition and Pharmacological Activity of Amethyst Sea Holly (Eryngium amethystinum L)

  • Mladen Duran Center for Biomedical Research, Faculty of Medicine
  • Relja Suručić Department of Pharmacognosy, Faculty of Medicine, University of Banja Luka, Banja Luka, The Republic of Srpska, Bosnia and Herzegovina
  • Biljana Tubić Department of Pharmaceutical Chemistry, Faculty of Medicine, Faculty of Medicine, University of Banja Luka, Banja Luka, The Republic of Srpska, Bosnia and Herzegovina
  • Ranko Škrbić Department of Pharmacology and Toxicology, Faculty of Medicine, University of Banja Luka, Banja Luka, The Republic of Srpska, Bosnia and Herzegovina
DOI: https://doi.org/10.5937/scriptamed56-57684

Sažetak


Eryngium amethystinum L is a plant which grows in Balkan and Apennine peninsulas. The aerial parts, roots and fruits are used in ethnopharmacology of Italy and Western Balkan countries. Traditional preparations of E amethystinum were used in treatment of oedema, malaria and gastrointestinal diseases. Essential oils and extracts were isolated from aerial parts and roots of E amethystinum and examined by antimicrobial, antioxidative and cytotoxic assays. Gas-chromatography analysis showed predominance of germacrene D and spathulenol in essential oils of E amethystinum aerial parts, which have contributed to strong cytotoxic activity, while the methanolic extract exhibited strong antioxidative and antimicrobial activity. This article summarises all existing knowledge regarding E amethystinum, its chemical composition and pharmacological activity.

 

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Objavljeno
2025/08/29
Broj časopisa
Vol. 56 Br. 4 (2025): Jul-Aug
Rubrika
Review article
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