Meeting the challenges of biological threats and bioweapons in the 21st century

  • Elizabeta S. Ristanović University of Defence, Military Medical Academy, Belgrade (Serbia)
  • Mubarak S.A. Burshaid Al-Dhaheri University “Union – Nikola Tesla”, School for Engineering Management, Belgrade (Serbia)
Keywords: weapons of mass-destruction (WMD), bio-weapons (BW), bioterrorism, ethics, Biological and Toxin Weapons Convention (BTWC)

Abstract


Biological warfare has attracted people since the earliest times. During the Cold War, bio-weapons were part of the arsenal of both world superpowers. The Convention prohibiting the production, storage, transfer and use of potential biological weapons (BWC) was signed 50 years ago. The question arises how sincere the signatory states were in its implementation. The rapid development of molecular biology has raised awareness about its potential misuse in terms of creating new and more dangerous bio-weapons, as well as the question of ethics in biomedical research. The anthrax campaign in the USA represents a turning point after which the use of weapons of mass destruction (WMD), including biological ones, has become part of the narrative that accompanies each war conflict. Epidemics and pandemics of avian and swine flu, Zika virus, SARS, MERS and COVID-19, as well as their implications, have proved the significance of a multidisciplinary approach to the study of microorganisms, their epidemiological, microbiological, genetic and antigenic characteristics, methods of their diagnosis, prevention and treatment, not only from the biomedical, but also from the security aspect. Perhaps the 50th anniversary is the right time to ask why the International Expert Body for controlling the implementation of the BTWC provisions has not been constituted yet.

References

Alberque, W. (2022). The US Arms Control Agenda: Impact on Europe. In: Arms Control and Europe (pp. 9-20). Springer, Cham.
Atlas, R. M., & Dando, M. (2006). The dual-use dilemma for the life sciences: perspectives, conundrums, and global solutions. Biosecurity and bioterrorism: biodefence strategy, practice, and science, 4(3), 276-286
Barenblatt, D. (2004). A plague upon humanity: The secret genocide of axis Japan’s germ warfare operation. New York: Harper Collins.
Barras, V., & Greub, G. (2014). History of biological warfare and bioterrorism. Clinical Microbiology and infection, 20(6), 497-502.
Block, S. M. (2001). The Growing Threat of Biological Weapons: The terrorist threat is very real, and it’s about to get worse. Scientists should concern themselves before it’s too late. American Scientist, 89(1), 28-37.
Brown, V. R., Miller, R. S., McKee, S. C., Ernst, K. H., Didero, N. M., Maison, R. M., ... & Shwiff, S. A. (2021). Risks of introduction and economic consequences associated with African swine fever, classical swine fever and Foot and Mouth disease: A review of the literature. Transboundary and emerging diseases, 68(4), 1910-1965.
BTWC, Available at: https://www.un.org/disarmament/biological-weapons/ Accessed: 15th September, 2022
Børsen Hansen, T. (2006). Academic and social responsibility of scientists. ISYP Journal on Science and World Affairs, 2(2), 71-92.
Carus, W. S. (2001). Bioterrorism and biocrimes: the illicit use of biological agents since 1900. Washington DC: Center for Counter proliferation Research at National Defence University, Revisited edition.
Carus, W. S. (2015). The history of biological weapons use: what we know and what we don’t. Health Security, 13(4), 219-255.
Cirincione, J., Wolfshal, J. B., & Raikumar, M. (2005). Deadly Arsenals: Tracking Weapons of Mass Destruction. Carnegie Endowment for International Peace. Ed. 2.
Danelyan, A. A. & Gulyaeva, E. E. (2022). Problems of Biosafety in Current International Law. Moscow Journal of International Law, (2), 66-84. [In Russian]
Danzig, R. (2012). Innovation, dual use, and security: managing the risks of emerging bio-logical and chemical technologies. MIT press.
DaSilva, E. J. (1999). Biological warfare, bioterrorism, biodefence and the biological and toxin weapons convention. Electronic Journal of Biotechnology, 2(3).
Drobysz, S. (2020). Verification and implementation of the Biological and Toxin Weapons Convention. The Nonproliferation Review, 27(4-6), 487-497.
Edwards, B., Novossiolova, T., Crowley, M., Whitby, S., Dando, M., & Shang, L. (2022). Meeting the challenges of chemical and biological weapons: strengthening the chem-ical and biological disarmament and non-proliferation regimes. Frontiers in Political Science, 15.
Eneh, O. C. (2012). Biological weapons-agents for life and environmental destruction. Research Journal of Environmental Toxicology, 6(3): 65-87.
Feakes, D. (2017). The Biological Weapons Convention. Revue Scientifique et Technique (International Office of Epizootics), 36(2), 621-628.
Grmek, M. D. (1979). Les ruses de guerre biologiques dans l’Antiquite. Rev Etud Grec, 92: 141–163. (In English)
Guillemin, J. (2004). Biological Weapons: From the invention of state-sponsored programs to contemporary bioterrorism. Columbia University Press.
Gutmann, A., & Wagner, J. (2010). New directions: The ethic of synthetic biology and emerging technologies. Presidential Commission for the Study of Bioethical Issues, Washington, December, 2010
Heinonen, O. (2016). Lessons learned from dismantlement of South Africa’s biological, chemical, and nuclear weapons programs. The Nonproliferation Review, 23(1-2), 147-162.
Hersman, R. K., Williams, H., & Claeys, S. (2022). Integrated Arms Control in an Era of Strategic Competition. Rowman & Littlefield.
Kaiser, J. (2005). Resurrected influenza virus yields secrets of deadly 1918 pandemic. Science, 310(5745), 28-29.
Kelle, A. (2022). Prohibiting Chemical and Biological Weapons. In: Prohibiting Chemical and Biological Weapons. Lynne Rienner Publishers.
Leach, B. (2021). Necessary Measures: Synthetic Biology & the Biological Weapons Convention. Stanford Technology Law Review, 25(1):141-165
LeClaire, R. D., & Pitt, M. L. M. (2005). Biological Weapons Defence. In: Biological Weapons Defence (pp. 41-61). Humana Press.
Leitenberg, M. (2001). Biological Weapons in the twentieth century: a review and analysis. Critical Reviews in Microbiology, 27(4), 267-320.
Leitenberg, M., Zilinskas, R. A., & Kuhn, J. H. (2012). The Soviet biological weapons program. In: The Soviet Biological Weapons Program. Harvard University Press.
Loch, J. K. (2002). Bombs, Bugs, Drugs and Thugs-Intelligence and America’s Quest for Security. NY: New York University Press, pp. 72-91
Mair, J. S., & Mair, M. (2006). Highlights & Happenings. Biosecurity and bioterrorism: bio-defence strategy, practice, and science, 4(4), 325-343.
Minogue, T. D., Koehler, J. W., Stefan, C. P., & Conrad, T. A. (2019). Next-generation sequencing for biodefence: biothreat detection, forensics, and the clinic. Clinical Chemistry, 65(3), 383-392.
Moore, J. N. (1972). Ratification of the Geneva Protocol on Gas and Bacteriological Warfare: A Legal and Political Analysis. Va. L. Rev., 58, 419.
Pearson, G. S. (2000). The essentials of biological threat assessment. Biological Warfare: Modern Offense and Defence, 55-83.
Petro, J. B. (2004). Intelligence support to the life science community: Mitigating threats from bioterrorism. Central Intelligence Agency. Washington DC. Studies in Intelligence, 48(3): 57-68
Ristanovic, E. (2009). Bioterrorism-risk and threat: The misuse of science. In: Counteraction to Chemical and Biological Terrorism in East European Countries (pp. 121-125). Springer, Dordrecht.
Ristanovic, E. (2015a). Bioterrorism: prevention and response. Beograd: University of Defence, Odbrana Media Center.
Ristanović, E. (2015b). Infectious agents as a security challenge: Experience of typhus, variola and tularemia outbreaks in Serbia. Bezbednost, 57(2), 5-20.
Ristanović, E., Gligić, A., Atanasievska, S., Protić Đokić, V., Jovanović, D., & Radunović, M. (2016). Smallpox as an actual biothreat: lessons learned from its outbreak in ex-Yu-goslavia in 1972. Annali dell Istituto Superiore di Sanita, 52(4), 587-597.
Ristanovic, E. (2018). Ethical aspects of bioterrorism and biodefence. In: Defence Against Bioterrorism (pp. 255-270). Springer, Dordrecht.
Ristanović, E., & Zejak, S. (2020). Health and Security aspects of COVID-19 in the prism of real time. Security Crises in the 21st Century and How to Manage Them COVID-19 Health and safety aspects, Volume 2, 10-22.
Robertson, A. G., & Robertson, L. J. (1995). From asps to allegations: biological warfare in history. Military Medicine, 160(8), 369-373.
Rode, A., Podbregar, I., & Ivanuša, T. (2010). Military intelligence and active defence against chemical, biological, radiological, and nuclear/explosives terrorism. Policing in Central and Eastern Europe–Social Control of Unconventional Deviance, 487-498.
Shang, L., Novossiolova, T., Crowley, M., Edwards, B., Whitby, S., & Dando, M. (2021). Biological and chemical security after COVID-19: options for strengthening the chemical and biological weapons disarmament and non-proliferation regimes.
Šuvaković, U. V., Baljošević, S. Ž., & Obradovic, Ž. V. (2014). Smallpox and globaliza-tion or the first achieved planetary goal. Vojnosanitetski pregled, 71(3), 301–306. DOI: 10.2298/VSP1403301S
Šuvaković, V. (2001). Return of Anthrax: “An Evil Spirit from the Bottle”. Srpski arhiv za celokupno lekarstvo, 129(9-10), 231–234. [In Serbian]
Šuvaković, V. (2001). Anthrax: A Biological Weapon for Terrorizing Civilians – Possibilities and Assumption. Acta Infectologica Yugoslavica, 6(3), 291–299. [In Serbian]
Walsh, P. F. (2018). Intelligence, biosecurity and bioterrorism. Springer.
Wheelis, M. (2002). Biological warfare at the 1346 siege of Caffa. Emerging Infectious Diseases, 8(9), 971-975.
Wheelis, M. (2006). Deadly cultures: biological weapons since 1945. Harvard University Press.
WHO Ebola Response Team. (2016). After Ebola in West Africa-unpredictable risks, pre-ventable epidemics. New England Journal of Medicine, 375(6), 587-596.
Wrigley, B. J., Salmon, C. T., & Park, H. S. (2003). Crisis management planning and the threat of bioterrorism. Public Relations Review, 29(3), 281-290.
Yadav, P. K. (2022). Evolving Dimension of Security: Bioterrorism. Unity Journal, 3(01), 266-277.

Published
2023/02/14
Section
Review scientific paper