Solitary basaloid follicular hamartoma: a report of two cases and a brief review of the literature

Danica Tiodorović; Andrija Jović; Sladjana  Cekić; Nataša Vidović; Tatjana Radević; Željko Mijušković

doi:10.2298/VSP240103011T

Danica Tiodorović University Clinical Center of Niš, Clinic of Dermatovenereology, Niš, Serbia; University of Niš, Faculty of Medicine, Niš, Serbia
Andrija Jović University Clinical Center of Niš, Clinic of Dermatovenereology, Niš, Serbia
Sladjana Cekić University Clinical Center of Niš, Clinic of Dermatovenereology, Niš, Serbia
Nataša Vidović University Clinical Center of Niš, Center for Pathology and Pathological Anatomy, Niš, Serbia
Tatjana Radević Military Medical Academy, Department of Dermatology and Venereology, Belgrade, Serbia
Željko Mijušković Military Medical Academy, Department of Dermatology and Venereology, Belgrade, Serbia

DOI: https://doi.org/10.2298/VSP240103011T

Keywords: dermoscopy;, diagnosis;, immunohisochemistry;, hamartoma;, histological techniques.

Abstract

Introduction. Basaloid follicular hamartoma (BFH) is a rare benign follicular malformation often clinically misdiagnosed. Patients with BFH demonstrate a variety of clinical manifestations and associated abnormalities. BFH may be a familial, congenital, or acquired condition with a localized or generalized distribution. Several clinical variants of generalized BFH are recognized, which may be associated with a diverse spectrum of abnormalities. Case report. We present two cases of solitary BFH in pediatric patients. The first patient was a 16-year-old boy with a history of autism spectrum disorder, admitted to our department for consultation due to a harmless dermal nevus on his face. The second patient was a six-year-old girl presented with a ten-month history of an asymptomatic, skin-colored papule located on the right nasolabial fold that gradually increased in size over time. Both cases were documented dermoscopically, and they were presented with a brief overview of the current literature. Conclusion. Considering the overlapping clinical, histological, and dermoscopic features of BFH with other benign and malignant lesions, its incidence in pediatric patients is probably higher than what is reported in the current literature.

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