Treatment of sudden sensorineural hearing loss with hyperbaric oxygenation – our experience

  • Zvonko M Živaljević
  • Ljubica Živić Clinic for Otorhinolaryngology, Clinical Center Kragujevac, Kragujevac, Serbia
  • Nataša Mihailović Institute for Public Health, Kragujevac, Serbia; §HBO Medical Center, Belgrade, Serbia
  • Miodrag Živković HBO Medical Center, Belgrade, Serbia
  • Branko Vorkapić HBO Medical Center, Belgrade, Serbia
  • Nenad Baletić Clinic for Otorhinolaryngology, Military Medical Academy, Belgrade, Serbia; Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
Keywords: hearing loss, sudden, hearing tests, hyperbaric oxygenation, recovery of function,

Abstract


Background/Aim. Sudden sensorineural hearing loss is manifested by the loss of hearing for more than 30 dB at three consecutive frequencies in the timeframe of 72 h. It is of unclear etiology and pathogenesis, which leads to the use of different therapeutic methods. Treatment protocols are not compliant, making it difficult to objectively quantify their impact. The aim of this study was to show the effect of hyperbaric oxygen therapy as the only method for the treatment of sudden sensorineural hearing loss. Methods. This retrospective study included 20 patients treated for sudden sensorineural hearing loss with hyperbaric oxygenation (HBO) in the period from 2004 to 2014. The study was conducted in the specialized medical clinic for hyperbaric and underwater medicine, HBO Medical Center in Belgrade. The patients were treated according to the following protocol: a session of 60 min at the pressure of 2 bars (2ATA) two times a day, a total of 30 sessions. Assessment of the therapy effects was performed by observing the change in the hearing threshold at the frequencies of 500, 1,000, 2,000 and 4,000 Hz at the end of the treatment. Results. After the completion of treatment according to the protocol, a full hearing recovery (total improvement of hearing damage or achieving final hearing threshold above 25 dB) was found in 11 (55%) of the patients. A partial recovery (hearing improvement of up to 15 dB, and a final hearing threshold below 45 dB) occurred in 4 (20%) of the patients. In 5 (25%) of the patients, improvement was not verified (there was no recovery or it was less than 5 dB). The average absolute hearing recovery was 24.94 dB. The mean relative hearing recovery was 65.45%. Conclusion. Because of the unclear multifactorial etiopathogenesis of this disease, there are many therapeutic protocols. Based on the results of our study HBO therapy could be recommended primarily as the treatment for sudden sensorineural hearing loss.

Author Biography

Zvonko M Živaljević
nacelnik ORL Kabineta

References

Živić LJ, Živić Đ, Stojanović S. Sudden hearing loss: Our experi-ence in the treatment with vasoactive agents. Srp Arh Celok Lek 2008; 136(3−4): 91−4.

Rambold H, Boenki J, Stritzke G, Wisst F, Neppert B, Helmchen C. Differential vestibular dysfunction in sudden unilateral hearing loss. Neurology 2005; 64(1): 148−51.

Shemirani NL, Schmidt M, Friedland DR. Sudden sensorineural hearing loss: An evaluation of treatment and management ap-proaches by referring physicians. Otolaryngol Head Neck Surg 2009; 140(1): 86−91.

Xenellis J, Nikolopoulos TP, Stavroulaki P, Marangoudakis P, An-droulakis M, Tsangaroulakis M, et al. Simultaneous and sequential bilateral sudden sensorineural hearing loss: Are they different from unilateral sudden sensorineural hearing loss. ORL J Otorhinolaryngol Relat Spec 2007; 69(5): 306−10.

Maslovara S. The primary treatment of idiopathic sudden hear-ing loss with oxygen under high pressure [thesis]. Zagreb: Faculty of Medicine, University of Zagreb; 1999. (Croatian)

Hughes GB, Freedman MA, Haberkamp TJ, Guay ME. Sudden sensorineural hearing loss. Otolaryngol Clin North Am 1996; 29(3): 393−405.

Mihailović-Kokić B, Todorović AJ, Kokić Z. Acute deafness-personal experience with therapy. Srp Arh Celok Lek 2002; 130(11−12): 394−6. (Serbian)

Furuhashi A, Matsuda K, Asahi K, Nakashima T. Sudden deaf-ness: Long-term follow-up and recurrence. Clin Otolaryngol Allied Sci 2002; 27(6): 458−63.

Živković M. Manual for Hyperbaric Medicine. Belgrade: Srpska zdravstvena organizacija; 2010. (Serbian)

Siegel LG. The treatment of idiopathic sudden sensorineural hearing loss. Otolaryngol Clin North Am 1975; 8(2): 467−73.

Byl FM. Sudden hearing loss: Eight years' experience and sug-gested prognostic table. Laryngoscope 1984; 94(5 Pt 1): 647−61.

Shaia FT, Sheehy JL. Sudden sensori-neural hearing im-pairment: A report of 1,220 cases. Laryngoscope 1976; 86(3): 389−98.

Čvorović LJ, Đerić D, Pavićević LJ, Probst R, Hegemann S. Does Does acute sensorineural deafness befall to urgent conditions? Vojnosanit Pregl 2009; 66(1): 35−8. (Serbian)

Živić LJ, Živić D, Đonović N. Sudden hearing loss: Our experi-ence in the treatment with vasoactive agents and corticosteroid drugs. Srp Arh Celok Lek 2012; 140(3−4): 153−8.

Racic G, Maslovara S, Roje Z, Dogas Z, Tafra R. Hyperbaric Oxy-gen in the Treatment of Sudden Hearing Loss. ORL J Otorhi-nolaryngol Relat Spec 2003; 65(6): 317−20.

Pezzoli M, Magnano M, Maffi L, Pezzoli L, Marcato P, Orione M, et al. Hyperbaric oxygen therapy as salvage treatment for sudden sensorineural hearing loss: a prospective controlled study. Eur Arch Otorhinolaryngol 2015; 272(7): 1659−66.

Dundar K, Gumus T, Ay H, Yetiser S, Ertugrul E. Effectiveness of hyperbaric oxygen on sudden sensorineural hearing loss: Prospective clinical research. J Otolaryngol 2007; 36(1): 32−7.

Čvorović LJ, Jovanović MB, Milutinović Z, Arsović N, Djeric D. Ran-domized prospective trial of hyperbaric oxygen therapy and intratympanic steroid injection as salvage treatment of sudden sensorineural hearing loss. Otol Neurotol 2013; 34(6): 1021−6.

Topuz E, Yigit O, Cinar U, Seven H. Should hyperbaric oxygen be added to treatment in idiopathic sudden sensorineural hearing loss. Eur Arc Otorhinolaryngol 2004; 261(7): 393−6.

Published
2017/06/02
Section
Short Report