Abdominal localization unicentric form Castleman disease - Case report

Boško Milev; Borka Milev; Zoran Kostić; Darko Mirković; Nenad Perišić; Olga Tasić; Marija Elez; Aleksandar Radunović; Milan Jovanović; Predrag Marić; Sanja Daišević; Rade Perelević; Maja Vulović

doi:10.2298/VSP150915045M

Boško Milev Clinics for General Surgery, Military Medical Academy, Belgrade, Serbia; Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
Borka Milev Clinic for General and Thoracic Surgery, Kragujevac, Clinical Center Kragujevac, Serbia
Zoran Kostić Clinics for General Surgery, Military Medical Academy, Belgrade, Serbia; Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
Darko Mirković Clinics for General Surgery, Military Medical Academy, Belgrade, Serbia; Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
Nenad Perišić Clinics for Gastroenterology and Hepathology, Military Medical Academy, Belgrade, Serbia
Olga Tasić Institute of Pathology and Forensic Medicine, Military Medical Academy, Belgrade, Serbia
Marija Elez Clinic for Hematology, Military Medical Academy, Belgrade, Serbia
Aleksandar Radunović Clinic for Orthopedic Surgery, Military Medical Academy, Belgrade, Serbia
Milan Jovanović Clinics for General Surgery, Military Medical Academy, Belgrade
Predrag Marić Clinic for Urology, Military Medical Academy, Belgrade, Serbia
Sanja Daišević Department of Anatomy and Forensic Medicine, Faculty of Medical Sciences, University of Kragujevac
Rade Perelević Clinic for Urology, Military Medical Academy, Belgrade, Serbia
Maja Vulović Department of Anatomy and Forensic Medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia

DOI: https://doi.org/10.2298/VSP150915045M

Keywords: giant lymph node hyperplasia, cecum, diagnostic techniques and procedures, diagnosis, differential, lymph nodes, digestive system surgical procedures,

Abstract

Introduction.

Castleman disease is a rare disease of the unknown etiology, occuring in two clinical forms: unicentric or multicentric form. It is characterized by the hyperplasia of lymph glands. In references the four pathohistological forms were described: hyaline vascular type, plasma-cell type, mixed type and recently recognized plasmablastic type. Changes are often localized in the mediastinum while in other parts of the body their incidence is less. Case report. At a man of 41, at MR enterography the change was noticed in the ileocecal area without the presence of subjective sympthoms of digestive tract and without loss of body mass. Due to the suspicion of stromal tumor, the surgical intervention was indicated. Pathohistological findings showed - Castelman lymphadenopathia reactiva mesenterii (plasma-cell type) which was in the unicentric form. There were only present the anaemia and increased value of sedimentation from the laboratory analyses. Conclusion. Abdominal localization of the unicentric plasma-cell form has a slight incidence, and surgical method of treatment represents the gold standard as it it was shown in our case.

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