Unicentrična forma Kastlemanove bolesti lokalizovane u stomaku

  • Boško Milev Clinics for General Surgery, Military Medical Academy, Belgrade, Serbia; Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
  • Borka Milev Clinic for General and Thoracic Surgery, Kragujevac, Clinical Center Kragujevac, Serbia
  • Zoran Kostić Clinics for General Surgery, Military Medical Academy, Belgrade, Serbia; Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
  • Darko Mirković Clinics for General Surgery, Military Medical Academy, Belgrade, Serbia; Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
  • Nenad Perišić Clinics for Gastroenterology and Hepathology, Military Medical Academy, Belgrade, Serbia
  • Olga Tasić Institute of Pathology and Forensic Medicine, Military Medical Academy, Belgrade, Serbia
  • Marija Elez Clinic for Hematology, Military Medical Academy, Belgrade, Serbia
  • Aleksandar Radunović Clinic for Orthopedic Surgery, Military Medical Academy, Belgrade, Serbia
  • Milan Jovanović Clinics for General Surgery, Military Medical Academy, Belgrade
  • Predrag Marić Clinic for Urology, Military Medical Academy, Belgrade, Serbia
  • Sanja Daišević Department of Anatomy and Forensic Medicine, Faculty of Medical Sciences, University of Kragujevac
  • Rade Perelević Clinic for Urology, Military Medical Academy, Belgrade, Serbia
  • Maja Vulović Department of Anatomy and Forensic Medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia
DOI: https://doi.org/10.2298/VSP150915045M
Ključne reči: giant lymph node hyperplasia||, ||kastlemanova bolest, cecum||, ||cekum, diagnostic techniques and procedures||, ||dijagnostičke tehnike i procedure, diagnosis, differential||, ||dijagnoza, diferencijalna, lymph nodes||, ||limfne žlezde, digestive system surgical procedures||, ||hirurgija digestivnog sistema, procedure,

Sažetak


Uvod. Kastlemanova bolest je retko oboljenje nepoznate etiologije koje se javlja u dve kliničke forme: unicentrična ili multicentrična. Odlikuje se hiperplazijom limfnih žlezda. U literaturi se opisuju četiri patohistološka oblika: hijalinovaskularni tip, plazmocitni tip, mešoviti tip i skorije prepoznat plazmablastični tip. Promene su najčešće lokalizovane u medijastinumu, dok se abdominalna lokalizacija znatno ređe javlja, što je i bio razlog za ovaj prikaz slučaja. Prikaz bolesnika. Kod muškarca, starog 41 godinu, na magnetnoj rezonantnoj (MR) enterografiji uočena je promena u ileocekalnoj regiji bez prisustva subjektivnih simptoma iz digestivnog trakta kao i bez gubitka telesne mase. Zbog sumnje na stromalni tumor, indikovana je hirurška intervencija. Patohistološki nalaz je pokazao Kastlemanovu lymphadenopathia reactiva mesenterii (plazma-ćelijski tip) u unicentričnoj formi. Od laboratorijskih analiza jedino su bile prisutne anemija i ubrzana sedimentacija eritrocita. Zaključak. Abdominalna lokalizacija unicentrične plazmocitne forme Kastlemanove bolesti javlja se retko, a hirurška metoda lečenja predstavlja zlatni standard što je potvrđeno ovim prikazom.

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Objavljeno
2017/06/28
Broj časopisa
Vol. 74 Br. 4 (2017)
Rubrika
Prikaz bolesnika