Heroin overdose – suicide or accident?
Abstract
Background/Aim. Suicide is a public health problem. Due to frequent overdose among drug addicts, there is a question about suicidality in this population. The aim of this study is to determine the specificity and distinctive factors in opiate addicts who have overdosed with an intention to commit suicide compared to addicts who have overdosed accidentally. Methods. The survey included 150 heroin addicts who were in the substitution program: 49 subjects who overdosed with a clear suicidal intention and 101 addicts who overdosed without suicidal intention. The subjects filled out the questionnaire about socio-demographic data and data regarding their addiction, the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) as well as the Manchester Short Assessment of Quality of Life (MANSA) questionnaire about the quality of life. For statistical analysis, Pearson's χ2 test, Student t-test and univariate variance analysis were used. Results. The addicts who attempted suicide wеre younger persons (29.7 vs. 36.3 years of age), started to take heroin earlier (17.8 vs. 21.3 years of age; p= 0.013), they use it for a longer period (14.1 vs. 9.2 years; p = 0.00) and take it intravenously for a longer period (11.6 vs. 6.5 years; p = 0.00). The suicide was preceded by a traumatic event (p = 0.015) and there were several attempts of suicide (p = 0.004). The quality of life regarding accommodation, friends and organization of their free time was assessed as not so good (p = 0.03). Conclusion. In accordance with the obtained data, it is necessary to design programs for the prevention of suicide among addicts in general and especially programs that would be aimed at younger addicts.
References
REFERENCES
Maloney E, Degenhardt L, Darke S, Mattick RP, Nelson E. Sui-cidal behaviour and associated risk factors among opioid-dependent individuals: A case-control study. Addiction 2007; 102(12): 1933‒41.
Kwon M, Yang S, Park K, Kim DJ. Factors that affect substance user's suicidal behavior: A view from the Addiction Severity Index in Korea. Ann Gen Psychiatry 2013; 12(1): 35.
Schneider B. Substance use disorders and risk for completed su-icide. Arch Suicide Res 2009; 13(4): 303‒16.
Darke S, Ross J, Lynskey M, Teesson M. Attempted suicide among entrants to three treatment modalities for heroin de-pendence in the Australian Treatment Outcome Study (ATOS): Prevalence and risk factors. Drug Alcohol Depend 2004; 73(1): 1‒10.
Borges G, Loera CR. Alcohol and drug use in suicidal behav-iour. Curr Opin Psychiatry 2010; 23(3): 195‒204.
Centers for Disease Control and Prevention. Injury prevention and control: Opioid overdose. Available from: www.cdc.gov/drugoverdose/opioids/heroin.html
National Institute on Drug Abuse. Heroin. 2015. [cited 2015 Sep 15]. Available from:
www.drugabuse.gov/drugs-abuse/heroin
International Classification of Diseases. Tenth Revision (ICD-10). Geneva: World Health Organization; 2010.
Priebe S, Huxley P, Knight S, Evans S. Application and Results of the Manchester Short Assessment of Quality of Life (Mansa). Int J Soc Psychiatry 1999; 45(1): 7‒12.
Butcher JN, Dahlstrom WG, Graham JR, Tellegen A, Kaemmer B. The Minnesota Multiphasic Personality Inventory-2 (MMPI-2): Manual for Administration and Scoring. Minneapolis, MN: University of Minnesota Press; 1989.
Wilcox HC, Conner KR, Caine ED. Association of alcohol and drug use disorders and completed suicide: An empirical review of cohort studies. Drug Alcohol Depend 2004; 76(Suppl): S11‒9.
Brooner RK, King VL, Kidorf M, Schmidt CW, Bigelow GE. Psy-chiatric and substance use comorbidity among treatment-seeking opioid abusers. Arch Gen Psychiatry 1997; 54(1): 71‒80.
Schuckit MA, Hesselbrock V. Alcohol dependence and anxiety disorders: What is the relationship? Am J Psychiatry 1994; 151(12): 1723‒34.
Kranzler HR, Liebowitz NR. Anxiety and depression in sub-stance abuse. Med Clin North Am 1998; 72(4): 867‒85.
Charney DA, Paraherakis AM, Negrete JC, Gill KJ. The impact of depression on the outcome of addictions treatment. J Subst Abuse Treat 1998; 15(2): 123‒30.
Montoya AD, Svikis D, Marcus SC, Suarez A, Tanielian T, Pincus HA. Psychiatric care of patients with depression and comor-bid substance use disorders. J Clin Psychiatry 2000; 61(9): 698‒705; quiz 706.
Galanter M, Castaneda R, Ferman J. Substance abuse among general psychiatric patients: Place of presentation, diagnosis and treatment. Am J Drug Alcohol Abuse 1998; 14(2): 211‒35.
Sundin M, Spak F, Spak L, Sundh V, Waern M. Substance use/abuse and suicidal behavior in young adult women: A population-based study. Subst Use Misuse 2011; 46(13): 1690‒9.
Haw CM, Hawton K. Problem drug use, drug misuse and delib-erate self-harm: Trends and patient characteristics, with a fo-cus on young people, Oxford, 1993-2006. Soc Psychiatry Psy-chiatr Epidemiol 2011; 46(2): 85‒93.
Srdanović-Maraš J, Kolundžija K, Dukić O, Šobot V, Marković J. Suicidal behavior in adolescent psychiatric population. Curr Top Neurol Psychiatr Relat Discip 2010; 3(18): 60‒4.
Bansal P, Gupta A, Kumar R. The Psychopathology and the So-cio-demographic Determinants of Attempted Suicide Patients. J Clin Diagn Res 2011; 5(5): 917‒20.
Nagendra Gouda MR, Rao SM. Factors related to attempted su-icide in Davanagere. Indian J Community Med 2008; 33(1): 15‒8.
Centers for Disease Control and Prevention. National Vital Statistics System. 2010. Multiple Cause of Death File. Hy-attsville, MD: US Department of Health and Human Services; 2012.
Bohnert AS, Roeder K, Ilgen MA. Unintentional overdose and suicide among substance users: A review of overlap and risk factors. Drug Alcohol Depend 2010; 110(3): 183‒92.
Ilgen MA, Burnette ML, Conner KR, Czyz E, Murray R, Cher-mack S. The association between violence and lifetime suicidal thoughts and behaviors in individuals treated for substance use disorders. Addict Behav 2010; 35(2): 111‒5.
Black DW, Blum N, Pfohl B, Hale N. Suicidal behavior in bor-derline personality disorder: Prevalence, risk factors, predic-tion, and prevention. J Pers Disord 2004; 18(3): 226‒39.
Darke S, Degenhardt L, Mattick R. Mortality among illicit drug users: epidemiology, causes and intervention. Cambridge: CambridgeUniversity Press; 2006.
Maloney E, Degenhardt L, Darke S, Nelson EC. Impulsivity and borderline personality as risk factors for suicide attempts among opioid-dependent individuals. Psychiatry Res 2009; 169(1): 16‒21.
Steil RI, Hinckers A, Bohus M. Comorbidity of personality dis-orders and posttraumatic stress disorder. Eur Psychiatry 2007; 22: S17.
Verona E, Patrick CJ, Joiner TE. Psychopathy, antisocial per-sonality, and suicide risk. J Abnorm Psychol 2001; 110(3): 462‒70.
Negredo L, Melis F, Herrero O. Psychopathy and suicidal behav-iour in a sample of mentally disordered offenders. Rev Esp Sanid Penit 2013; 15(1): 3‒7. (Spanish)
Dawson DA, Li TK, Chou SP, Grant BF. Transitions in and out of alcohol use disorders: Their associations with conditional changes in quality of life over a 3-year follow-up interval. Al-cohol Alcohol 2009; 44(1): 84‒92.
Donovan D, Mattson ME, Cisler RA, Longabaugh R, Zweben A. Quality of life as an outcome measure in alcoholism treatment research. J Stud Alcohol Suppl 2005; (15): 119‒39; discussion 92‒3.
Smith KW, Larson MJ. Quality of life assessments by adult sub-stance abusers receiving publicly funded treatment in Massa-chusetts. Am J Drug Alcohol Abuse 2003; 29(2): 323‒35.