Rare locations of metastastatic renal cell carcinoma: A presentation of three cases

Novak Milović; Miodrag Lazić; Predrag Aleksić; Dragan Radovanović; Vladimir Bančević; Slaviša Savić; Dušica Stamenković; Dušan Spasić; Branko Košević; Mirko Jovanovic; Dragoljub Perović

doi:10.2298/2008

Novak Milović Department of Urology, Military Medical Academy, Belgrade, Serbia, Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
Miodrag Lazić Department of Urology, Medical Center „Dr Dragiša Mišović-Dedinje“, Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Predrag Aleksić Department of Urology, Military Medical Academy, Belgrade, Serbia, Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
Dragan Radovanović Department of Surgery, Medical Center „Dr Dragiša Mišović-Dedinje“, Belgrade, Serbia
Vladimir Bančević Department of Urology, Military Medical Academy, Belgrade, Serbia, Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
Slaviša Savić Department of Urology, Medical Center „Dr Dragiša Mišović-Dedinje“, Belgrade, Serbia;
Dušica Stamenković Department of Anesthesia and Intensive Care, Military Medical Academy, Belgrade, Serbia
Dušan Spasić Department of Surgery, Medical Center „Dr Dragiša Mišović-Dedinje“, Belgrade, Serbia
Branko Košević Department of Urology, Military Medical Academy, Belgrade, Serbia
Mirko Jovanovic Military Medical Academy, Urology Clinic
Dragoljub Perović Clinic of Urology and Nephrology, Clinical Center of Montenegro, Podgorica, Montenegro

DOI: https://doi.org/10.2298/2008

Keywords: carcinoma, renal cell, neoplasm metastasis, urologic surgical procedures, treatment outcome,

Abstract

Introduction. Metastatic renal cell carcinoma (RCC) frequently spreads not only to neighboring lymph nodes, but also to distant organs, including the lungs, liver, bones and brain. Case report. We presented three cases of RCC with colon metastasis. In the first, 63-year-old patient, after left nephrectomy followed with lyphadenectomy in paraaortic lymph node, left hemicolectomy was done due to RCC metastasis in rectosigmoid colon. In the second, 35-year-old patient, left radical nephrectomy was followed two years later with partial right nephrectomy, lung metastasectomy, small bowel and coecum resection and right orchiectomy all as separate procedures in different time intervals. The patient died from brain and bone metastases two years after the first surgery. The third, 35-year-old patient, had right nephrectomy followed by repeted lymphadenectomies after 6, 12 and 24 months. Four years later RCC spreaded to coecum and right hemicolectomy was performed. Conclusion. RCC treated with nephrectomy should be carefully followed up with imaging methods as a proper treatment of RCC metastases to distant organs could be important for a patient survival.

Author Biography

Novak Milović, Department of Urology, Military Medical Academy, Belgrade, Serbia, Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia

Dept of Urology

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