Gigantic spermatocytic seminoma – A rare tumor of germ cell origin
Abstract
Introduction.
Spermatocytic seminoma represents a rare hystologic type of malignant testicular germ cell tumor with slow course and low malignant potential. Case report. We presented a 69-year-old patient with atypical clinical presentation of spermatocytic seminoma initially diagnosed as gigantic hydrocoellae which compromised walking. After long term evolution clincal picture presented with signs and symptoms of acute scrotum. Preoperative echosonography was performed and the diagnosis of testicular infiltrative tumor was established. After that left scrotal orchiectomy was performed. Patohistological examination revealed spermatocytic seminoma. Conclusion. Inspite good prognosis there is a low probability of development of high grade malignancy sinchronous sarcoma within the testis with a high potential for lymphogenic and hematogenic dissemination. Individual approach is necessary in accordance with the pathohistological diagnosis.References
Mostofi FK. Testicular tumors: Epidemiologic, etiologic, and pathologic features. Cancer 1973; 32(5): 1186−201.
Eble JN, Sauter G, Epstein JI, Sesterhenn IA. World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon: IARC Press; 2004. str. 2412-2414
Mills S. Sternberg's Diagnostic Pathology, 5th ed. Philadel-phia: Lippincott Williams & Wilkins; 2009.
Maluccio M, Einhorn LH, Goulet RJ. Surgical therapy for testicular cancer metastatic to the liver. HPB (Oxford) 2007; 9(3): 199−200.
Aggarwal N, Parwani AV. Spermatocytic seminoma. Arch Pathol Lab Med 2009; 133(12): 1985−8.
Steiner H, Gozzi C, Verdorfer I, Mikuz G, Bartsch G, Ho-bisch A. Metastatic spermatocytic seminoma-an extremely rare disease: Part 2. Eur Urol 2006; 49(2): 408−9.
Floyd C, Ayala AG, Silva EG, Logothetis CJ. Spermatocytic seminoma with associated sarcoma of the testis. Cancer 1988; 61(2): 409−14.
Albores-Saavedra J, Huffman H, Alvarado-Cabrero I, Ayala AG. Anaplastic variant of spermatocytic seminoma. Hum. Pathol 1996; 27(7): 650−5.
True LD, Otis CN, Delprado W, Scully RE, Rosai J. Sperma-tocytic seminoma of testis with sarcomatous transforma-tion: A report of five cases. Am J Surg Pathol 1988; 12(2): 75−82.
Robinson A, Bainbridge T, Kollmannsberger C. A spermato-cytic seminoma with rhabdomyosarcoma transformation and extensive metastases. Am J Clin Oncol 2007; 30(4): 440−1.
Wetherell D, Lawrentschuk N, Gyomber D. Spermatocytic Seminoma With Sarcoma: An Indication for Adjuvant Chemotherapy in Localized Disease. Korean J Urol 2013; 54(12): 884−7.
Matoska J, Talerman A. Spermatocytic seminoma associ-ated with rhabdomyosarcoma. Am J Clin Pathol 1990; 94(1): 89−95.
