Epithelioid sarcoma of femoral nerve – A case report

Dejan Ivanov; Mirjana Živojinov; Milan Ranisavljević

doi:10.2298/VSP160819350I

Dejan Ivanov Clinical Center of Vojvodina, Clinic for Abdominal, Endocrine Surgery and Transplantation, Novi Sad, Serbia
Mirjana Živojinov Clinical Center of Vojvodina, Department for Pathology, Novi Sad, Serbia ; Oncology Institute of Vojvodina, Sremska Kamenica, Serbia
Milan Ranisavljević Clinical Center of Vojvodina, Department for Pathology, Novi Sad, Serbia; Faculty of Medicine, Novi Sad, Serbia

DOI: https://doi.org/10.2298/VSP160819350I

Ključne reči: sarkomi;, meka tkiva;, n. femoralis;, dijagnostičke tehnike i procedure;, hirurgija, operativne procedure;, radioterapija.

Sažetak

Uvod. Epiteloidni sarkom je redak, sporo rastući maligni tumor mekog tkiva i pronalazi se u oko 1% svih mezenhimnih tumora. Prikazujemo slučaj epiteloidnog sarkoma femoralnog nerva, koji je prema našim saznanjima, prvi ovakav opisan slučaj. Prikaz bolesnika. Bolesnica stara 44 godine, primljena je na pregled sa jakim bolovima u levoj nozi. Na snimku magnetne rezonance tumor se prezentovao kao nodus dimenzija 8 cm na levom femoralnom nervu, između bočnog slabinskog i ilijačnog mišića, bez infiltracije mišićnih fascija i tetiva. Četiri uvećana limfna čvora, opisana u ilijačnoj jami, bila su suspektna na prisustvo sekundarnih depozita. Urađena je radikalna hirurška ekscizija tumora i transekcija nerva sa lokalnom limfadenektomijom. Patohistološka analiza potvrdila je dijagnozu epiteloidnog sarkoma, a tumor je pokazivao izrazitu imunohistohemijsku pozitivnost na anti-pan citokeratin antitelo (AE1/AE3), vimentin, karcinomski antigen 125 (CA125), anti-citokeratin antitelo (MNF116), antigen progenitorskih ćelija hematopoeze (CD34) i epitelni membranski antigen (EMA). Nakon operacije bolesnica je primila radioterapiju bez hemioterapije. Šest meseci nakon operativnog lečenja kod bolesnice nije bilo lokalnog recidiva i udaljenih metastaza. Zaključak. Inicijalna široka resekcija i adjuvantna radioterapija je ključna u tretmanu epiteloidnog sarkoma.

Reference

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Epiteloidni sarkom femoralnog nerva

Sažetak

Reference