Faktori koji doprinose održavanju humane Q groznice u Vojvodini, Srbija
Sažetak
Uvod/Cilj. Kju groznica je rasprostranjena širom sveta, a otkrivena je kako među ljudima, tako i među domaćim sisarima. Cilj ovog istraživanja je bio da se opišu epidemiološke karakteristike Kju groznice i da se proceni povezanost između pojave Kju groznice i klimatskih uslova. Metode. Sprovedena je deskriptivna epidemiološka studija upotrebom podataka Instituta za javno zdravlje Vojvodine, Veterinarskog instituta iz Novog Sada i Republičkog hidrometerološkog zavoda Srbije, u periodu od 2006. do 2015. godine. Rezultati. Od ukupno 272 slučaja humane Kju groznice, 114 (41,9%) pacijenata su bili uzrasta od 20 do 39 godina. Od januara do maja registrovano je ukupno 193 (71,0%) slučaja oboljenja. U Srednjem i Južnom Banatu uočena je jaka korelacija pozitivnog smera između porasta broja obolelih od Kju goznice i porasta prosečne jačine vetra (ρ= 0,69719 i ρ=0,62303), dok je jaka korelacija negativnog smera, između prosečnih vrednosti padavina i broja registrovanih slučajeva Kju groznice, registrovana u Srednjem Banatu, Južnom Banatu i Sremu (ρ = -0,78033, ρ = -0,70675 i ρ = -0,70431). Tokom desetogodišnjeg perioda, utvrđena je i jaka korelacija pozitivnog smera između broja obolelih od Kju groznice i broja obolele stoke, odnosno obolelih ovaca u Sremskom okrugu (r = 0,7989 i r = 0,7966). Direktan kontakt sa domaćim životinjama bio je najčešći put prenosa Kju groznice u Vojvodini. Zaključak. Pravovremena razmena informacija između sektora za zdravstvenu zaštitu životinja i sektora za zaštitu zdravlja ljudi, kao i između susednih zemalja, od ključnog je značaja za odgovarajući i rani odgovor na epidemijsko javljanje oboljenja, posebno tokom vetrovitih i suvih meseci u godini. Osim toga, za osobe koje su izložene riziku od obolevanja, neophodno je sprovođenje stalne edukacije o smanjenju rizika od prenošenja infekcije.
Reference
Lai CH, Chang LL, Lin JN, Liao MH, Liu SS, Lee HH, at al. Association of Human Q Fever with Animal Husbandry, Tai-wan, 2004-2012. Emerg Infect Dis 2015; 21(12): 2217–20.
de Valk H. Q fever: new insights, still many queries. Euro Surveill. 2012; 17(3): pii=20062.
Maurin M, Raoult D. Q fever. Clin Microbiol Rev 1999; 12(4): 518–53.
Palmela C, Badura R, Valadas E. Acute Q fever in Portugal. Epidemiological and clinical features of 32 hospitalized pa-tients. Germs 2012; 2(2): 43–59.
Medić S, Kaluski DN, Seguljev Z, Obrenović J, Rudan P, Lazarević M, at al. Q fever outbreak in the village of Noćaj, Srem County, Vojvodina Province, Serbia, January to February 2012. Euro Surveill. 2012; 17(15): pii: 20143.
Lang GH. Coxiellosis (Q fever) in animals. In: Marrie TJ, edi-tor. Q fever, the disease. Boca Raton: CRC press; 1990. p. 23–48.
Sánchez J, Souriau A, Buendía AJ, Arricau-Bouvery N, Martínez CM, Salinas J, at al. Experimental Coxiella burnetii infection in pregnant goats: a histopathological and immunohistochemi-cal study. J Comp Pathol 2006; 135(2–3): 108–15.
Berri M, Souriau A, Crosby M, Rodolakis A. Shedding of Coxiel-la burnetii in ewes in two pregnancies following an episode of Coxiella abortion in a sheep flock. Vet Microbiol 2002; 85(1): 55–60.
Espejo E, Gil-Díaz A, Oteo JA, Castillo-Rueda R, García-Alvarez L, Santana-Báez S, at al. Clinical presentation of acute Q fever in Spain: seasonal and geographical differences. Int J Infect Dis 2014; 26: 162–4.
Hellenbrand W, Breuer T, Petersen L. Changing epidemiology of Q fever in Germany, 1947-1999. Emerg Infect Dis 2001; 7(5): 789–96.
Parker NR, Barralet JH, Bell AM. Q fever. Lancet. 2006; 367(9511): 679–88.
Arricau-Bouvery N1, Rodolakis A. Is Q fever an emerging or re-emerging zoonosis? Vet Res 2005; 36(3): 327–49.
Hatchette TF, Marrie TJ. Atypical manifestations of chronic Q fever. Clin Infect Dis 2001; 33(8): 1347–51.
Tissot-Dupont H, Torres S, Nezri M, Raoult D. Hyperendemic focus of Q fever related to sheep and wind. Am J Epidemiol 1999; 150(1): 67–74.
Tissot-Dupont H, Amadei MA, Nezri M, Raoult D. Wind in No-vember, Q fever in December. Emerg Infect Dis 2004; 10(7): 1264–9.
Schimmer B, Ter Schegget R, Wegdam M, Züchner L, de Bruin A, Schneeberger PM, at al. The use of a geographic information sys-tem to identify a dairy goat farm as the most likely source of an urban Q-fever outbreak. BMC Infect Dis 2010; 10: 69.
Nusinovici S, Frössling J, Widgren S, Beaudeau F, Lindberg A. Q fever infection in dairy cattle herds: increased risk with high wind speed and low precipitation. Epidemiol Infect 2015; 143(15): 3316–26.
Harris P, Eales KM, Squires R, Govan B, Norton R. Acute Q fe-ver in northern Queensland: variation in incidence related to rainfall and geographical location. Epidemiol Infect 2013; 141(5): 1034–8.
Republic Hydrometeorological Service of Serbia (RHMS). Available from: http://www.hidmet.gov.rs/eng/meteorologija/klimatologija.php [accessed 2016 June 20]
Institute of Public Health of Vojvodina. Communicable diseases in Vojvodina, 2006-2015. Annual report. Belgrade: Institute of Public Health of Vojvodina; 2016. (Serbian)
World Organisation for Animal Health (OIE) 1 & 2, electron-ic version 2016. chapter 2.1.16. Available at: http://www.oie.int/fileadmin/Home/eng/Health_standards/tahm/2.01.16_Q_FEVER.pdf.
Ćosić G, Đekić J, Đurić P, Šeguljev Z, Petrović M, Rajčević S. Epi-demiological characteristics of Q fever in Vojvodina Province, Serbia, 1985-2009. Arch Biol Sci (Belgrade) 2012; 64(4): 1363-68.
Luksić B, Punda-Polić V, Ivić I, Bradarić I, Bradarić N. Clinical and epidemiological features of hospitalized acute Q fever cases from Split-Dalmatia County (Croatia), 1985-2002. Med Sci Monit 2006; 12(3): CR126–31.
Punda-Polić V, Radulović S. Sero-survey of Q fever in the north-western part of Bosnia and Herzegovina. Croat Med J 1997; 38: 345–47.
EFSA and ECDC (European Food Safety Authority and Eu-ropean Centre for Disease Prevention and Control), 2015. The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2013. EFSA J 2015; 13(1): 3991.
WHO. Centralized information system for infectious diseases (CISID). Available from: http://www.data.euro.who.int/cisid/. 2016.
Maltezou HC, Raoult D. Q fever in children. Lancet Infect Dis 2002; 2(11): 686–91.
McQuiston JH, Holman RC, McCall CL, Childs JE, Swerdlow DL, Thompson HA. National surveillance and the epidemiology of human Q fever in the United States, 1978-2004. Am J Trop Med Hyg 2006; 75(1): 36–40.
Monno R, Fumarola L, Trerotoli P, Cavone D, Giannelli G, Rizzo C, at al. Seroprevalence of Q fever, brucellosis and leptospiro-sis in farmers and agricultural workers in Bari, Southern Italy. Ann Agric Environ Med 2009; 16(2): 205–9.
Leone M, Honstettre A, Lepidi H, Capo C, Bayard F, Raoult D. Effect of sex on Coxiella burnetii infection: protective role of 17beta-estradiol. J Infect Dis 2004; 189(2): 339–45.
Garner MG, Longbottom HM, Cannon RM, Plant AJ. A review of Q fever in Australia 1991-1994. Aust N Z J Public Health 1997; 21(7): 722–30.
Reedijk M, van Leuken JP, van der Hoek W. Particulate matter strongly associated with human Q fever in The Netherlands: an ecological study. Epidemiol Infect 2013; 141(12): 2623–33.
de Rooij MM, Borlée F, Smit LA, de Bruin A, Janse I, Heederik DJ, at al. Detection of Coxiella burnetii in Ambient Air after a Large Q Fever Outbreak. PLoS One 2016; 11(3): e0151281.
Španović M. Trends of the established occupational communi-cable diseases among workers in the territory of Vojvodina [dissertation]. Novi Sad: Faculty of Medicine, University of Novi Sad; 2016. (Serbian)