Uticaj socioekonomskih faktora na kvalitet života i funkcionalno oštećenje bolesnika lečenih od orofaringealnog karcinoma

  • Jovica Milovanović Clinical Center of Serbia, Clinic for Otorhinolaryngology and Maxillofacial Surgery, Belgrade, Serbia
  • Dragoslava Andrejić Primary Heathcare Center “Dr Simo Milošević”, Belgrade, Serbia
  • Ana Jotić Clinical Center of Serbia, Clinic for Otorhinolaryngology and Maxillofacial Surgery, Belgrade, Serbia
  • Vojko Djukić Clinical Center of Serbia, Clinic for Otorhinolaryngology and Maxillofacial Surgery, Belgrade, Serbia
  • Oliver Tošković University of Belgrade, Faculty of Philosophy, Laboratory for Experimental Psychology, Belgrade, Serbia
  • Katarina Savić-Vujović University of Belgrade, Faculty of Medicine, Department of Pharmacology, Belgrade, Serbia
  • Bojan Pavlović Clinical Center of Serbia, Clinic for Otorhinolaryngology and Maxillofacial Surgery, Belgrade, Serbia
  • Goran Stojković Clinical Center of Serbia, Clinic for Otorhinolaryngology and Maxillofacial Surgery, Belgrade, Serbia
  • Bojan Banko Clinical Center of Serbia, Center for Radiology and Magnetic Resonance Imaging, Belgrade, Serbia
  • Andjela Milovanović University of Belgrade, Faculty of Medicine, Belgrade, Serbia
  • Vera Artiko Clinical Center of Serbia, Institute for Nuclear Medicine, Belgrade, Serbia
DOI: https://doi.org/10.2298/VSP170210134M
Ključne reči: papillomaviridae;, socijalno-ekonomski faktori;, farinks neoplazme;, kvalitet života;, lečenje, ishod.

Sažetak


Uvod/Cilj. Incidencija orofaringealnih karcinoma se povećavala tokom poslednje decenije, a epidemiologija promenila sa pojavom humanog papiloma virusa (HPV) kao bitnog faktora rizika od ovih karcinoma. Potrebno je ustanoviti bolje terapeutske izbore za specifične grupe bolesnika koji se leče od orofaringealnog karcinoma. Cilj ove studije bio je da se procene kvalitet života i funkcionalne performanse, kao i uticaj različitih demografskih faktora, stadijuma bolesti i tipa terapija na te parametre kod bolesnika sa orofaringealnim karcinomom kod kojih je postignuta uspešna lokoregionalna kontrola, godinu dana posle sprovedene terapije. Metode. Studija je uključila 87 bolesnika koji su odgovorili na upitnike o kvalitetu života i funkcionalnim performansama: European Organization for Research and Treatment of Cancer Quality-of Life-Questionnaire-C30 – EORTC QLQ-C30), European Organization for Research and Treatment of Cancer Quality of- Life Questionnaire-Head and Neck 35 (EORTC QLQ-H&N35) i Karnofsky Performance Scale (KPS), 12 do 14 meseci posle završenog onkološkog tretmana. Rezultati. Specifične grupe bolesnika značajno su se razlikovale u skorovima na upitnicima za kvalitet života posle lečenja. Faktori koji su bili povezani sa slabijim rezultatima su bili ženski pol, život bez partnera, nivo obrazovanja, zaposlenost i HPV status. Zaključak. Kliničari bi trebali da uzmu u obzir socio-ekonomske faktore i HPV status u planiranju postoperativnog oporavka kod bolesnika lečenih od orofaringealnog karcinoma. Pol bolesnika, nivo obrazovanja i zaposlenost su faktori koji nose određen nivo rizika koji je povezan sa nižim nivoom kvaliteta života kod ovih bolesnika.

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2021/05/20
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