Faktori povezani sa depresijom kod bolesnika sa dijabetesom melitusom tip II
Sažetak
Apstrakt
Uvod/Cilj. Merenje povezanosti depresije i dijabetesa melitusa tip 2, primenom Patient Health Questionnaire 9 (PHQ-9) upitnika, nije do sada rađeno u Crnoj Gori. Cilj ovog rada je bio da se proceni prevalencija depresije kod bolesnika sa dijabetesom tip 2 i da se identifikuju faktori rizika povezani sa prisustvom depresije. Metode. Studija preseka sprovedena je u Opštoj bolnici Bijelo Polje, u periodu od jula do septembra 2015. godine. Studijom je bio obuhvaćeno 70 osoba starijih od 35 godina sa dijagnozom dijabetesa od najmanje šest meseci. Za procenu prisustva depresije korišćen je upitnik PHQ-9. Sve varijable koje su bile značajno povezane sa prisustvom depresije (p < 0,05) ušle su u model multivarijantne logističke regresije. Rezultati. Komorbiditeti su se značajno češće javljali kod osoba sa depresijom (χ2 = 5,40; p = 0,020). Trajanje dijabetesa više od pet godina bilo je značajno povezano sa prisustvom depresije (χ2 = 12,48; p < 0,001). Depresija je bila značajno češća kod fizički neaktivnih osoba (χ2 = 10,74; p = 0,005). Prisustvo komplikacija dijabetesa u vidu dijabetične polineuropatija (χ2 = 6,04; p = 0,014) i katarakte (χ2 = 5,351; p = 0,021) je takođe bilo statistički značajno povezano sa prisustvom depresije. Multivarijantna logistička regresija je pokazala da su trajanje bolesti preko pet godina i katarakta nezavisni prediktori depresije. Zaključak. Istraživanjem je ustanovljeno da su faktori rizika od pojave depresije bili trajanje dijabetesa preko pet godina i prisustvo katarakte. Kako je depresija ozbiljno oboljenje i faktor rizika od pojave mnogih hroničnih bolesti, najbolja prevencija su njena rana detekcija i lečenje.
Reference
REFERENCES
World Health Organization. What is depression. Available from: www.who.int/mental_health/management/depression/definition/en
World Health Organization. Depression, fact sheets. Available from: www.who.int. depression/factsheets
Republička stručna komisija za izradu i implementaciju vodiča dobre kliničke prakse. Nacionalni vodič dobre kliničke prakse za dijagnostiku i lečenje depresije. Beograd: Ministarstvo zdravlja Republike Srbije; 2011.
Stanković Ž, Jašović-Gašić M. Comorbidity of depression and type 2 diabetes: Risk factors and clinical significance. Vojnosa-nit Pregl 2010; 67(6): 493–500.
Li C, Ford ES, Strine TW, Mokdad AH. Prevalence of depres-sion among U.S. adults with diabetes: findings from the 2006 behavioral risk factor surveillance system. Diabetes Care 2008; 31(1): 105–7.
de Groot M, Anderson R, Freedland KE, Clouse RE, Lustman PJ. Association of depression and diabetes complications: a meta-analysis. Psychosom Med 2001; 63(4): 619–30.
Sneed JR, Culang-Reinlieb ME. The vascular depression hypothesis: an update. Am J Geriatr Psychiatry 2011; 19(2): 99–103.
Schmitz N, Gariépy G, Smith KJ, Malla A, Wang J, Boyer R, et al. The pattern of depressive symptoms in people with type 2 di-abetes: a prospective community study. J Psychosom Res 2013; 74(2): 128–34.
Janssen EP, Köhler S, Stehouwer CD, Schaper NC, Dagnelie PC, Sep SJ, et al. The Patient Health Questionnaire-9 as a Screening Tool for Depression in Individuals with Type 2 Diabetes Mellitus: The Maastricht Study. J Am Geriatr Soc 2016; 64(11): e201–6.
Larijani B, Khoram M, Bayat S, Gorgani KM, Bandarian F, Ak-hondzadeh S, et al. Association between depression and di-abetes. German J Psychiatry 2004; 7: 62–5.
Willborn RJ, Barnacle M, Maack B, Petry N, Werremeyer A, Strand MA. Use of the 9-item patient health questionnaire for depression assessment in primary care patients with type 2 diabetes. J Psychosoc Nurs Ment Health Serv 2016; 54(1): 56–63.
van der Zwaan GL, van Dijk SEM, Adriaanse MC, van Marwijk HWJ, van Tulder MW, Pols AD, et al. Diagnostic accuracy of the Patient Health Questionnaire-9 for assessment of depres-sion in type II diabetes mellitus and/or coronary heart disease in primary care. J Affect Disord 2016; 190: 68–74.
Raval A, Dhanaraj E, Bhansali A, Grover S, Tiwari P. Prevalence and determinants of depression in type 2 diabetes patients in a tertiary care centre. Indian J Med Res 2010; 132: 195–200.
Schmitz N, Messier L, Nitka D, Ivanova A, Gariepy G, Wang J, et al. Factors associated with disability and depressive symptoms among individuals with diabetes: a community study in Que-bec. Psychosomatics 2011; 52(2): 167–77.
Roy T, Lloyd CE, Parvin M, Mohiuddin KG, Rahman M. Preva-lence of co-morbid depression in out-patients with type 2 di-abetes mellitus in Bangladesh. BMC Psychiatry 2012; 12: 123.
Das-Munshi J, Stewart R, Ismail K, Bebbington PE, Jenkins R, Prince MJ. Diabetes, common mental disorders, and disability: findings from the UK National Psychiatric Morbidity Survey. Psychosom Med 2007; 69(6): 543–50.
Miyaoka Y, Miyaoka H, Motomiya T, Kitamura S, Asai M. Impact of sociodemographic and diabetes-related characteristics on depressive state among non-insulin-dependent diabetic patients. Psychiatry Clin Neurosci 1997; 51(4): 203–6.
Mezuk B, Eaton WW, Golden SH, Ding Y. The influence of educational attainment on depression and risk of type 2 diabetes. Am J Public Health 2008; 98(8): 1480–5.
Reddy P, Philpot B, Ford D, Dunbar JA. Identification of depres-sion in diabetes: the efficacy of PHQ-9 and HADS-D. Br J Gen Pract 2010; 60(575): e239–45.
Von Korff M, Katon W, Lin EH, Simon G, Ludman E, Oliver M, et al. Potentially modifiable factors associated with disability among people with diabetes. Psychosom Med 2005; 67(2): 233–40.
Nasser J, Habib F, Hasan M, Khalil N. Prevalence of depression among people with diabetes attending diabetes clinics at pri-mary health settings. Bahrain Med Bull 2009; 31: 1–7.
Kawakami N, Takatsuka N, Shimizu H, Ishibashi H. Depressive symptoms and occurrence of type 2 diabetes among Japanese men. Diabetes Care 1999; 22(7): 1071–6.
Knol MJ, Twisk JW, Beekman AT, Heine RJ, Snoek FJ, Pouwer F. Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis. Diabetologia 2006; 49(5): 837–45.
Cosgrove MP, Sargeant LA, Griffin SJ. Does depression increase the risk of developing type 2 diabetes? Occup Med (Lond) 2008; 58(1): 7–14.
Brown LC, Majumdar SR, Newman SC, Johnson JA. History of depression increases risk of type 2 diabetes in younger adults. Diabetes Care 2005; 28(5): 1063–7.