Korelacije između simptoma, nalaza endoskopije nosa i kompjuterizovane tomografije kod bolesnika sa hroničnim rinosinuzitisom bez nosne polipoze
Sažetak
Uvod/ Cilj. Hronični rinosinuzitis (HRS) je jedno od najčešćih hroničnih oboljenja koje se dijagnostikuje na osnovu simptoma bolesti, endoskopije nosa i kompjuterizovane tomografije (KT) nosa i paranazalnih sinusa. Postoje dve forme rinosinuzitisa: HRS sa polipozom nosa (HRSsPN) i HRS bez polipoze nosa (HRSbPN). Cilj rada je bio da se utvrdi da li postoje korelacije između simptoma, nalaza endoskopije nosa i KT kod bolesnika sa HRSbPN. Metode. Istraživanjem je obuhvaćeno 110 bolesnika sa HRSbPN. Intenzitet tegoba je bio procenjen na vizuelnoj analognoj skali (VAS); endoskopskim pregledom nosa procenjeno je stanje nosne sluznice i prisustvo sekreta u nosu, a korišćenjem KT nosa i paranazalnih sinusa utvrđene su vrednosti Lund-Mackay skora. Za statističku obradu podataka korišćen je Pirsonov koeficijent korelacije. Rezultati. Težina bolesti u celosti (r = 0,509) i sekrecija iz nosa (r = 0,562) umereno su korelirale sa vrednostima KT skora. Zapušenost nosa (r = 0,354) i osećaj oslabljenog ili izgubljenog mirisa (r = 0,324) blago su korelirali sa vrednostima KT skora, dok je korelacija između osećaja bola/pritiska u licu (r = 0,218) i KT skora bila vrlo slaba. Težina bolesti u celosti (r = 0,717) i sekrecija iz nosa (r = 0,821) snažno su korelirale sa nalazima endoskopije nosa. Zapušenost nosa (r = 0,525) je imala umerenu korelaciju sa nalazom endoskope nosa, dok su osećaj bola/pritiska u licu (r = 0,345) i osećaj oslabljenog ili izgubljenog mirisa (r = 0,394) blago korelirali sa nalazom endoskopijom nosa. Korelacija između nalaza endoskopije nosa i KT bila je umerena (r = 0,630). Zaključak. Težina bolesti u celosti i sekrecija iz nosa, u odnosu na druge tegobe, značajnije koreliraju, kako sa nalazom endoskopije nosa tako i sa KT skorom. Značajnije korelacije između simptoma i nalaza endoskopije nosa u odnosu na korelacije između simptoma i KT skora, uz postojanje umerene korelacije između nalaza endoskopije nosa i KT skora, omogućavaju da se KT nosa i paranazalnih sinusa koristi samo u jasno definisanim situacijama.
Reference
Collins JG. Prevalence of selected chronic conditions: United States, 1990-1992. Vital Health Stat 10 1997; (194): 1–89.
Gliklich RE, Metson R. The health impact of chronic sinusitis in patients seeking otolaryngologic care. Otolaryngol Head Neck Surg 1995; 113(1): 104–9.
Bhattacharyya N, Kepnes LJ. Additional disease burden from hay fever and sinusitis accompanying asthma. Ann Otol Rhinol Laryngol 2009; 118(9): 651–5.
Blackwell DL, Collins JG, Coles R. Summary health statistics for U.S. adults: National Health Interview Survey, 1997. Vital Health Stat 10 2002; (205): 1–109.
Fokkens WJ, Lund VJ, Mullol J, Bachert C, Alobid I, Baroody F, et al. EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology 2012; 50(1): 1–12.
Bonfils P, Halimi P, Le Bihan C, Norès JM, Avan P, Landais P. Correlation between nasosinusal symptoms and topographic diagnosis in chronic rhinosinusitis. Ann Otol Rhinol Laryngol 2005; 114(1 Pt 1): 74–83.
Pokharel M, Karki S, Shrestha BL, Shrestha I, Amatya RC. Cor-relations between symptoms, nasal endoscopy computed to-mography and surgical findings in patients with chronic rhi-nosinusitis. Kathmandu Univ Med J (KUMJ) 2013; 11(43): 201–5.
Lim M, Lew-Gor S, Darby Y, Brookes N, Scadding G, Lund VJ. The relationship between subjective assessment instruments in chronic rhinosinusitis. Rhinology 2007; 45(2): 144–7.
Hopkins C, Browne JP, Slack R, Lund V, Brown P. The Lund-Mackay staging system for chronic rhinosinusitis: how is it used and what does it predict? Otolaryngol Head Neck Surg 2007; 137(4): 555–61.
Hastan D, Fokkens WJ, Bachert C, Newson RB, Bislimovska J, Bockelbrink A, et al. Chronic rhinosinusitis in Europe - an un-derestimated disease. A GA2LEN study. Allergy 2011; 66(9): 1216–23.
Ryan WR, Ramachandra T, Hwang PH. Correlations between symptoms, nasal endoscopy, and in-office computed tomogra-phy in post-surgical chronic rhinosinusitis patients. Laryngo-scope 2011; 121(3): 674–8.
Deepthi NV, Menon U, Menon I. Correlations and comparison between repeat computed tomography scores, endoscopy scores and symptomatic improvement before and after endo-scopic sinus surgery: a pilot study. Clin Rhinol Int J 2013; 6: 32–40.
Birch SD, Saleh HA, Wodehouse T, Simpson IN, Mackay IS. As-sessing the quality of life for patients with chronic rhinosinusi-tis using the “Rhinosinusitis Disability Index”. Rhinology 2001; 39(4): 191–6.
Kenny TJ, Duncavage J, Bracikowski J, Yildirim A, Murray JJ, Tan-ner SB. Prospective analysis of sinus symptoms and correlation with paranasal computed tomography scan. Otolaryngol Head Neck Surg 2001; 125(1): 40–3.
Bhattacharyya N, Lee LN. Evaluating the diagnosis of chronic rhinosinusitis based on clinical guidelines and endoscopy. Oto-laryngol Head Neck Surg 2010; 143(1): 147–51.
Nair S. Correlation between symptoms and radiological find-ings in patients of chronic rhinosinusitis: a modified radiologi-cal typing system. Rhinology 2009; 47(2): 181–6.
Gairola P, Bist S, Mishra S, Agrawal V. Assessment of quality of life in patients of chronic rhinosinusitis. Clin Rhinol An Int J 2014; 7: 96–9.
Baumann I, Blumenstock G, Zalaman IM, Praetorius M, Klingmann C, Sittel C, et al. Impact of gender, age, and comorbidities on quality of life in patients with chronic rhinosinusitis. Rhinolo-gy 2007; 45(4): 268–72.
Naidoo Y, Tan N, Singhal D, Wormald PJ. Chronic rhinosinusitis assessment using the Adelaide Disease Severity Score. J Laryn-gol Otol 2013; 127(Suppl 2): S24–8.
Basu S, Georgalas C, Kumar BN, Desai S. Correlation between symptoms and radiological findings in patients with chronic rhinosinusitis: an evaluation study using the Sinonasal Assess-ment Questionnaire and Lund-Mackay grading system. Eur Arch Otorhinolaryngol 2005; 262(9): 751–4.
Holbrook EH, Brown CL, Lyden ER, Leopold DA. Lack of sig-nificant correlation between rhinosinusitis symptoms and spe-cific regions of sinus computer tomography scans. Am J Rhi-nol 2005; 19(4): 382–7.
Wabnitz DA, Nair S, Wormald PJ. Correlation between pre-operative symptom scores, quality-of-life questionnaires, and staging with computed tomography in patients with chronic rhinosinusitis. Am J Rhinol 2005; 19(1): 91–6.
Rosbe KW, Jones KR. Usefulness of patient symptoms and nasal endoscopy in the diagnosis of chronic sinusitis. Am J Rhinol 1998; 12(3): 167–71.
Kantarci M, Karasen R, Alper F, Onbas O, Okur A, Karaman A. Remarkable anatomic variations in paranasal sinus region and their clinical importance. Eur J Radiol 2004; 50(3): 296–302.
Bolger WE, Butzin CA, Parsons DS. Paranasal sinus bony ana-tomic variations and mucosal abnormalities: CT analysis for endoscopic sinus surgery. Laryngoscope 1991; 101 (1 Pt 1): 56–64.
Liu Z, Wang H, Lu X, You XG, Gao Q, Cui Y. Correlation be-tween rhinosinusitis symptoms and objective sinus examina-tions. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2007; 21(11): 483–5. (Chinese)
Nass RL, Holliday RA, Reede DL. Diagnosis of surgical sinusi-tis using nasal endoscopy and computerized tomography. Laryngoscope 1989; 99(11): 1158–60.
Casiano RR. Correlation of clinical examination with comput-er tomography in paranasal sinus disease. Am J Rhinol 1997; 11(3): 193–6.
Lohiya SS, Patel SV, Pawde AM, Bokare BD, Sakhare PT. Com-parative study of diagnostic nasal endoscopy and ct paranasal sinuses in diagnosing chronic rhinosinusitis. Indian J Otolaryn-gol Head Neck Surg 2016; 68(2): 224–9.
Stankiewicz JA, Chow JM. A diagnostic dilemma for chronic rhinosinusitis: definition accuracy and validity. Am J Rhinol 2002; 16(4): 199–202.
