Recurrent painful ophthalmoplegic neuropathy: A report on the patient from the Romani population and 82-year-old patient

Svetlana Miletić-Drakulić; Dejan Zoran Aleksić

doi:10.2298/VSP171225023M

Svetlana Miletić-Drakulić PhD, University of Kragujevac, Serbia, Faculty of Medical Sciences, Department of Neurology
Dejan Zoran Aleksić MD, University of Kragujevac, Serbia, Faculty of Medical Sciences, Department of Neurology

DOI: https://doi.org/10.2298/VSP171225023M

Ključne reči: migrena, oftalmoplegična;, odrasle osobe;, stare osobe, 80 i više godina;, dijagnoza;, lečenje lekovima;, romi;, lečenje, ishod

Sažetak

Uvod. Aktuelni dijagnostički kriterijumi za rekurentnu bolnu oftalmoplegičnu neuropatiju (RPON) su najmanje dva ataka jednostrane glavobolje, udružene sa ipsilateralnom parezom jednog, dva ili sva tri kranijalna nerva (III, IV ili VI). Do sada nije prikazan slučaj RPON u populaciji Roma. Najstariji bolesnik sa RPON, prikazan u literaturi, imao je 74 godine. Prikaz bolesnika. Prvi bolesnik je bio 31-godišnji muškarac romske nacionalnosti koji je lečen tokom tri epizode RPON, sa parezom III kranijalnog nerva u tokom jedne epizode i VI kranijalnog nerva na različitim stranama, u toku druge dve epizode. Sva ispitivanja su bila uredna, osim povišenih vrednosti lipida u serumu i imunoglobulina G (IgG) na citomegalovirus (CMV IgG), IgG na toksoplazmu gondi, IgG na Epstein–Barr virus (EVB) i IgG na Varicela zoster virus. Drugi bolesnik je bio 82-godišnji muškarac sa dve epizode RPON i zahvećenim VI kranijalnim nervom na različitim stranama. Sva ispitivanja su bila uredna, osim povišenih vrednosti IgG na Herpes simplex virus tip 1, CMV IgG, IgG na toksoplazmu gondi, EBV IgG i IgG na Varicela zoster virus i lakunarnih ishemijskih lezija koje je imao na snimku magnetne rezonance (MR) mozga. Oba bolesnika su lečena kortikosteroidnom terapijom. Oporavak je bio kompletan nakon svih pet epizoda RPON. Zaključak. Ne postoje podaci o učestalosti RPON među pripadnicima romske nacionanosti. Pojava RPON u najstarijem životnom dobu je veoma retka. RPON bi trebalo imati u vidu kao jednu od dijagnostičkih opcija kod ovih grupa bolesnika. Novi prikazi bolesnika ili revijalni radovi o RPON su neophodni da bi se razjasnila priroda same bolesti.

Reference

Headache Classification Committee of the International Headache So-ciety (IHS). The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia 2013; 33(9): 629‒808.

Headache Classification Committee of the International Headache So-ciety (IHS). The international classification of headache dis-orders. Cephalalgia 2004; 2(1): 1–160.

Jiménez-Sánchez S, Fernández-de-las-Peñas C, Jiménez-García R, Hernández-Barrera V, Alonso-Blanco C, Palacios-Ceña D et al. Prevalence of migraine headaches in the Romany popula-tion in Spain: sociodemographic factors, lifestyle and co-morbidity. J Transcult Nurs 2013; 24(1): 6‒13.

Gelfand AA, Gelfand JM, Prabakhar P, Goadsby PJ. Ophthal-moplegic "migraine" or recurrent ophthalmoplegic cranial neuropathy: new cases and a systematic review. J Child Neurol 2012; 27(6): 759‒66.

Podgorac A, Zidverc-Trajkovic J, Jovanovic Z, Ristic A, Radojicic A, Pavlovic A, et al. Tolosa-Hunt syndrome: is it really necessary to show granuloma? – The report on eight cases. Vojnosan-it Pregl 2017; 74(3): 287‒93.

Ostergaard JR, Møller HU, Christensen T. Recurrent ophthal-moplegia in childhood: diagnostic and etiologic considera-tions. Cephalalgia 1996; 16(4): 276‒9.

Crevits L, Verschelde H, Casselman J. Ophthalmoplegic mi-graine: an unresolved problem. Cephalalgia 2006; 26(10): 1255‒9.

Tocco P, Fenzi F, Cerini R, Monaco S. Adult-onset migraine-related ophthalmoplegia and omolateral fetal-type posterior cerebral artery. BMJ Case Rep 2011; 2011: pii: bcr1020114930.

Lavin PJ, Aulino JM, Uskavitch D. "Ophthalmoplegic mi-graine" with reversible MRI enhancement of the cisternal sixth cranial nerve. J Neuroophthalmol 2009; 29(2): 151‒3.

Kim R, Kim JH, Kim E, Yang HK, Hwang JM, Kim JS. Oculo-motor nerve tumors masquerading as recurrent painful ophthalmoplegic neuropathy: Report of two cases and re-view of the literature. Cephalalgia 2015; 35(9): 825‒30.

Hung CH, Chang KH, Chu CC, Liao MF, Chang HS, Lyu RK, et al. Painful ophthalmoplegia with normal cranial imaging. BMC Neurol 2014; 14: 7.

Hansen SL, Borelli-Møller L, Strange P, Nielsen BM, Olesen J. Ophthalmoplegic migraine: diagnostic criteria, incidence of hospitalization and possible etiology. Acta Neurol Scand 1990; 81(1): 54‒60.

Chakravarty A, Mukherjee A. Ophthalmoplegic migraine: A critical analysis and a new proposal. Ann Indian Acad Neu-rol 2012; 15(Suppl 1): S2‒6.

Ravishankar K. Ophthalmoplegic migraine: Still a diagnostic dilemma? Curr Pain Headache Rep 2008; 12(4): 285–91.

Lal V, Sahota P, Singh P, Gupta A, Prabhakar S. Ophthal-moplegia with migraine in adults. Is it ophthalmoplegic mi-graine? Headache 2009; 49(6): 838–50.

Manzouri B, Sainani A, Plant G, Lee J, Sloper J. The aetiology and management of long-lasting sixth nerve palsy in oph-thalmoplegic migraine. Cephalalgia 2007; 27(3): 275‒8.

Vasconcelos LP, Stancioli FG, Leal JC, da Silva A, Gómez RS, Teixeira AL. Ophthalmoplegic migraine: a case with recur-rent palsy of the abducens nerve. Headache 2008; 48(6): 961‒4.

Mucchiut M, Valentinis L, Provenzano A, Cutuli D, Bergonzi P. Adult onset ophthalmoplegic migraine with recurrent sixth nerve palsy: A case report. Headache 2006; 46(10): 1589‒90.

Sayg S, Savaş GT, Erol İ. Recurrent painful ophthalmoplegic neuropathy: a case report. Cukurova Med J 2014; 39(4): 938‒41. (Turkish)

Rekurentna bolna oftalmoplagička neuropatija – prikaz bolesnika iz romske populacije i 82-godišnjeg bolesnika

Sažetak

Reference