Procena uticaja životnog doba na kvalitet života bolesnica sa rakom dojke pre i posle hirurškog lečenja

  • Sanja Kostić Clinical Hospital Center ʺBežanijska kosaʺ, Department of Medical Oncology, Belgrade, Serbia
  • Zafir Murtezani Clinical Hospital Center ʺBežanijska kosaʺ, Department of Medical Oncology , Belgrade, Serbia
  • Zoran Andrić Clinical Hospital Center ʺBežanijska kosaʺ, Department of Medical Oncology, Belgrade, Se
  • Nebojša Ivanović Clinical Hospital Center ʺBežanijska kosaʺ, Department of Surgery, Belgrade, Serbia
  • Zoran Kozomara Institute for Oncology and Radiology of Serbia, Department of Surgery, Belgrade, Serbia
  • Marko Kostić Clinical Center of Serbia, Clinic for Thoracic Surgery, Belgrade, Serbia
  • Vesna Miličić University of Kragujevac, Faculty of Medical Science, Department of Dermatovenerology, Kragujevac, Serbia
  • Sanja Kocić University of Kragujevac, Faculty of Medical Science, Department of Social Medicine, Kragujevac, Serbia
Ključne reči: dojka, neoplazme, kvalitet života, životno doba, hirurgija, operativne procedure, ankete i upitnici

Sažetak


Uvod/Cilj. Rak dojke čini oko 25% svih malignih tumora žena, sa incidencom u porastu. Novije dijagnostičke proce­dure i terapijski modaliteti lečenja rezultiraju uspešnijim lečenjem i većom stopom preživljavanja žena obolelih od raka dojke. Cilj savremenog lečenja podrazumeva, ne samo bolje preživljavanje, već i bolji kvalitet života. Cilj ove stu­dije bio je da se proceni kvalitet života bolesnica obolelih od karcinoma dojke pre i posle hirurške intervencije u zavisno­sti od njihovog životnog doba pri postavljanju dijagnoze. Metode. Analizirali smo kvalitet života 170 bolesnica sa karcinomom dojke (43 starosti do 50 godina i 127 starosti 50 i više godina) u I i II kliničkom stadijumu bolesti, mesec dana pre i nakon hirurškog lečenja, primenom uputnika Evropske organizacije za istraživanje i lečenje karcinoma (EORTC QLQ-C30) i specifične verzije upitnika za karci­nom dojke (EORTC QLQ-BR23). Rezultati. Analizom upitnika QLQ-C30 pokazano je da je hirurško lečenje značajno negativno uticalo na kvalitet života bolesnica u obe starosne grupe. Nezavisno od hirurškog lečenja, između bolesnica mlađih i starijih postojale su razlike u seksualnom funkcionisanju i seksualnom uživanju, sa višim skorovima u grupi mlađih žena. Analiza uticaja hirurškog lečenja na kva­litet života, primenom upitnika QLQ-BR23, pokazala je sta­tistički značajno pogoršanje kvaliteta života nakon hirurškog lečenja u skoro svim domenima kod bolesnica obe starosne grupe. Zaključak. Rezultati našeg istraživanja ukazali su na statistički značajne razlike u kvalitetu života između žena obe starosne grupe nezavisno od hirurškog lečenja i to u domenima seksualnog funkcionisanja i uživanja. Pritom je bolji kvalitet života bio u grupi žena mlađe životne dobi. Hirurško lečenje bolesnice sa karcino­mom dojke negativno je uticalo na kvalitet života, nezavisno od starosnog doba.

Biografija autora

Sanja Kostić, Clinical Hospital Center ʺBežanijska kosaʺ, Department of Medical Oncology, Belgrade, Serbia

MD (Specialist in Internal medicine - oncologist)

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2021/03/04
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