Melanom i skvamocelularni karcinom kože nastali na ožiljku od opekotine

  • Nikola Ostojić Military Medical Academy, Clinic for Plastic Surgery and Burns, Belgrade, Serbia; University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade, Serbia
  • Nenad Stepić Military Medical Academy, Clinic for Plastic Surgery and Burns, Belgrade, Serbia; University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade, Serbia
  • Milica Rajović Military Medical Academy, Clinic for Plastic Surgery and Burns, Belgrade, Serbia; University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade, Serbia
  • Jovana Končar Institute for Oncology and Radiology of Serbia, Department of Surgery, Belgrade, Serbia
  • Marijan Novaković Academy of Medical Sciences of the Serbian Medical Society, Belgrade, Serbia
DOI: https://doi.org/10.2298/VSP200812099O
Ključne reči: karcinom, planocelularni;, dijagnoza, rana;, dijagnoza, diferencijalna;, histološke tehnike;, melanom;, opekotine;, ožiljak.

Sažetak


Uvod. Maligni tumori kože nastali na terenu ožiljaka od opekotina opisani su kod 2% bolesnika, a planocelularni karcinom kože (karcinom skvamoznih ćelija kože, cutaneous squamous cell carcinoma ‒ cSCC) je najčešći. On se javlja nekoliko godina posle opekotine kao posledica maligne transformacije ćelija u hronično inflamiranom tkivu. Razvoj melanoma na ožiljku od opekotine je veoma redak; opisano je nekoliko slučajeva sinhronog ili metahronog pojavljivanja melanoma i cSCC. Melanom i cSCC mogu se istovremeno pojaviti na ožiljku od opekotine, kao i na regiji sa autotransplantatom kože. Prikaz bolesnika. Prikazali smo muškarca starog 67 godina koji je imao opekotinu od ključale vode u 14. Godini života. U 60. godini života, na mestu ožiljka od opekotine, kliničkim i dermoskopskim pregledom posumnjano je na melanom, a nakon ekscizije i histopatološke analize potvrđena je sumnja i postavljena dijagnoza melanoma (površinsko šireći, Breslow 0,87 mm, sa ulceracijom, pT1b). Nakon postavljene dijagnoze bolesnik je redovno kontrolisan svakih šest meseci. Tokom treće godine praćenja, zbog sumnje na cSCC, učinjena je kompletna hirurška ekscizija i dijagnoza cSCC je potvrđena histopatološkom analizom. Zaključak. Prikazani slučaj naglašava važnost dugotrajnog dermatološkog praćenja osoba nakon opekotina kože, i ranu dijagnozu i odgovarajuće hirurško lečenje nastalih malignih karcinoma kože jer se na taj način poboljšava ishod lečenja ovih bolesnika.

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Objavljeno
2022/05/11
Broj časopisa
Vol. 79 Br. 3 (2022)
Rubrika
Prikaz bolesnika