The Procena kvaliteta života bolesnika lečenih zbog hroničnog pankreatitisa

  • Saša Dragović Military medical Academy
  • Maja Vulović University of Kragujevac, Faculty of Medical Sciences, Department of Anatomy and Forensic Medicine, Kragujevac,
  • Dušica Stamenković Military Medical Academy, Clinic for Anaesthesiology and Intensive Care
  • Nemanja Rančić §University of Defence, Faculty of Medicine of the Military Medical Academy
  • Miroslav Mitrović Military Medical Academy, Clinic for General Surgery
  • Mihailo Bezmarević Military Medical Academy, Clinic for General Surgery
  • Milan Jovanović Military Medical Academy, Clinic for General Surgery
  • Ivan Pantić Military Medical Academy, Clinic for General Surgery
  • Zoran Rujanovski Military Medical Academy, Clinic for General Surgery
  • Sanja Lepić University of Defence, Faculty of Medicine of the Military Medical Academy
  • Boško Milev Military Medical Academy, Clinic for General Surgery
Ključne reči: lečenje lekovima, pankreatitis, hronični, kvalitet života, hirurgija, operativne procedure, ankete i upitnici

Sažetak


Uvod

 

Hronični pankreatitis (CP) izaziva zapaljenske promene u tkivu pankreasa, što rezultira nepovratnim oštećenjem tkiva. Razvijaju se bol, endokrina i egzokrina insuficijencija pankreasa, čime se smanjuje kvalitet života pacijenata. Cilj studije je da se istraži uloga hirurškog lečenja u poboljšanju kvaliteta života pacijenata sa CP.

 

Metode

 

Procena kvaliteta života 50 pacijenata kojima je dijagnostikovana CP izvršena je korišćenjem sertifikovanog upitnika Euro Quality of life-5 dimension-5 level (EuroQol-5D-5L) prevedenog na srpski jezik. Pacijenti su popunili upitnik. Pacijenti su podeljeni u dve grupe (konzervativna - CT naspram hirurške - ST), a sva poređenja su napravljena između grupa.

 

Rezultati

 

Pacijenti  u B stadijumu hroničnog pankreatitisa su podeljeni u dve grupe od 25 pacijenata. Prva grupa pacijenata sa CP lečena je konzervativno, a druga grupa hirurškim pristupom. Prosečna starost u hirurški lečenoj grupi (ST) iznosila je 48.56 ± 11.91, a u konzervativno lečenoj grupi (CT) 51.08 ± 11.61 (p = 0.452). Odnos muškaraca i žena u ST grupi bio je 18/7, a u CT grupi 22/3 (p = 0.289). Bol u ST grupi bio je prisutan kod 23 pacijenta, a u CT grupi kod 18 pacijenata (p = 0.141). Gubitak apetita u ST grupi bio je prisutan kod 7 pacijenata, a u CT grupi kod 10 pacijenata (p = 0.256). Gubitak kilograma u obe grupe bio je jednak (p = 1.000). Na osnovu EuroQol-5D-5L utvrđene su značajne razlike (p <0.001) između grupe u pokretljivosti i bolu / nelagodnosti; kod anksioznosti / depresije (p = 0.003); u samopomoći (p = 0.004); kod Uobičajene aktivnosti (p = 0.008).

 

Zaključak

 

CP značajno smanjuju kvalitet života (QoL) pacijenata koji se leče konzervativno ili hirurškim pristupom. Ova studija je pokazala da je hirurško lečenje korisnije za kvalitet života kod pacijenata sa CP nego konzervativni pristup.

 

Ključne reči: hronični pankreatitis; bol; hirurški tretman; Kvalitet života.

 

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2022/11/01
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