Uticaj cross-linking procedure na kornealne optičke aberacije kod bolesnika sa keratokonusom

  • Mirko Resan Univerzitet odbrane u Beogradu, Medicinski fakultet VMA, Klinika za ocne bolesti
  • Željka Cvejić University of Novi Sad, Faculty of Sciences, Department of Physics, Novi Sad, Serbia
  • Philipp Baenninger Cantonal Hospital of Lucerne, Department of Ophthalmology, Lucerne, Switzerland
  • Farhad Hafezi Elza Institute, Dietikon, Switzerland University of Geneva, Faculty of Medicine, Geneva, Switzerland
  • Horace Massa Swiss Eye Research Foundation, Eye Clinic Orasis, Reinach, Switzerland
  • Miroslav Vukosavljević University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade, Serbia
  • Bojan Pajić University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade, Serbia
DOI: https://doi.org/10.2298/VSP210620079R
Ključne reči: rožnjača;, kornealna topografija;, keratokonus;, hirurgija, oftalmološka, procedure;, vid, oštrina.

Sažetak


Uvod/Cilj. Procedura corneal cross-linking (CXL) pokazuje najbolje efekte u stabilizovanju rožnjače i zaustavljanju napretka ektatičnog procesa. Cilj rada bio je da se ispita uticaj CXL procedure na optičke aberacije višeg reda – higher-order aberrations (HOAs) i poboljšanje funkcije vida u lečenju keratokonusa. Metode. Standardna CXL procedura sa uklanjanjem epitela rožnjače izvedena je kod 19 bolesnika korišćenjem energije jačine 3 mW/cm2 u trajanju od 30 min. Kod svakog bolesnika rožnjača je snimljena na Pentacam aparatu pre procedure i jedan i 6 meseci posle CXL procedure. Ispitivani su najbolje korigovana oštrina vida, topografski podaci i vrednosti optičkih aberacija. Rezultati. Utvrđeno je značajno smanjenje vrednosti vertikalne kome sa -1,03 ± 1,89 preoperativno na -0,74 ± 1,73 šest meseci postoperativno (p = 0,004) i sferne aberacije sa  -0,22 ± 1,05 preoperativno na -0,08 ± 1,13 postoperativno (p = 0,002). Vrednosti root mean square (RMS) HOAs takođe su se značajno smanjile sa 2,31 ± 1,82 preoperativno na 2,26 ± 1,84 šest meseci postoperativno (p = 0,001). Najbolje korigovana oštrina vida poboljšana je sa 0,43 ± 0,15 preoperativno na 0,71 ± 0,19 šest meseci postoperativno (p < 0,001). Zaključak. Procedura CXL je uspešna metoda lečenja keratokonusa koja značajno smanjuje određene aberacije talasnog fronta rožnjače, posebno vertikalnu komu, sferne aberacije i RMS, i dovodi do značajnog poboljšanja oštrine vida.

Biografija autora

Mirko Resan, Univerzitet odbrane u Beogradu, Medicinski fakultet VMA, Klinika za ocne bolesti

oftalmolog

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Objavljeno
2022/12/23
Broj časopisa
Vol. 79 Br. 11 (2022): Vojnosanitetski pregled
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Originalni članak