Quality of life of patients with primary open-angle glaucoma, primary angle closure glaucoma, and pseudoexfoliation glaucoma in Central Serbia

Elizabeta Marčeta; Tatjana Šarenac Vulović; Nenad Petrović; Dejan Vulović; Marija Trenkić; Danijela Randjelović; Dušan Todorović

doi:10.2298/VSP220729030M

Elizabeta Marčeta Clinical Hospital Center Zvezdara, Department of Internal Medicine, Belgrade, Serbia
Tatjana Šarenac Vulović University Clinical Center Kragujevac, Clinic for Ophthalmology; University of Kragujevac, Faculty of Medical Sciences, Department of Ophthalmology
Nenad Petrović University Clinical Center Kragujevac, Clinic for Ophthalmology; University of Kragujevac, Faculty of Medical Sciences, Department of Ophthalmology
Dejan Vulović University Clinical Center Kragujevac Center for Plastic Surgery, Kragujevac, Serbia; University of Kragujevac, Faculty of Medical Sciences, Department of Surgery, Kragujevac, Serbia
Marija Trenkić University Clinical Center Niš, Clinic for Ophthalmology, Niš, Serbia
Danijela Randjelović Aero Medical Institute, Belgrade, Serbia
Dušan Todorović University Clinical Center Kragujevac, Clinic for Ophthalmology; University of Kragujevac, Faculty of Medical Sciences, Department of Ophthalmology

DOI: https://doi.org/10.2298/VSP220729030M

Ključne reči: glaukom, otvorenog ugla, glaukom, zatvorenog ugla, eksfolijativni sindrom, kvalitet života, ankete i upitnici

Sažetak

Uvod/Cilj. Oštećenje vida uzrokovano glaukomom ima snažan negativan uticaj na mentalno i fizičko zdravlje. Cilj studije bio je da se ispita uticaj primarnog glaukoma otvorenog ugla (PGOU), primarnog glaukoma zatvorenog ugla (PGZU) i pseudoeksfolijativnog glaukoma (PEG) na kvalitet života (KŽ) bolesnika u centralnoj Srbiji. Metode. U ovoj studiji preseka bila su uključena 102 bolesnika koji su lečeni zbog PGOU, PGZU ili PEG. Bolesnici su bili podeljeni u tri grupe (PGOU, PGZU i PEG) u zavisnosti od tipa glaukoma i posmatrani su šest meseci. Podaci o KŽ učesnika prikupljeni su korišćenjem upitnika National Eye Institute Visual Functioning Questionnaire 25 (NEI VFQ-25). Korišćenjem odgovarajućeg algoritma izračunat je ukupan rezultat iz upitnika NEI VFQ-25 za svaku grupu. Rezultati. Parametri funkcije vida bili su statistički značajno niži u PEG grupi u poređenju sa ostalim ispitivanim grupama (PEG: 61,1 ± 12,6; PGOU: 71,6 ± 17,9; PGZU: 75,7 ± 11,6), p < 0,001. Opšte zdravlje, bol u očima, vid na daljinu, socijalno funkcionisanje, periferni vid, smanjena sposobnost u svakodnevnim aktivnostima i zavisnost od drugih, takođe su bili statistički značajno niži u PEG grupi. Najbolja oštrina vida na blizinu izmerena je u PGOU grupi (76,2 ± 21,2). Najviša srednja vrednost glaukomnog ispada vidnog polja zabeležena je u PEG grupi bolesnika (14,5 ± 3,6 dB). Zaključak. Istraživanje je pokazalo da su bolesnici sa PEG imali statistički značajno lošiji KŽ u poređenju sa bolesnicima koji su bolovali od PGOU i PGZU. Najniži skor po pojedinim oblastima ispitivanja po upitniku NEI VFQ-25 bio je kod bolesnika sa PEG, kada je u pitanju bilo opšte zdravlje bolesnika, osećaj bola u očima, vid na daljinu, kao i u domenu socijalnog i svakodnevnog funkcionisanja. Dobijeni rezultati ukazuju da treba preduzeti ozbiljne mere za popravljanje kvaliteta života bolesnika sa glaukomom.

Reference

Zhou H, Shen Z. The definition of glaucoma. In: Zhou H, Shen Z, editors. Intraocular pressure and Glaucoma. Wuhan, Chi-na: Hubei Science & Technology Press; 2010. p. 8–11.

Liu SA, Zhao ZN, Sun NN, Han Y, Chen J, Fan ZG. Transi-tions of the understanding and definition of primary glauco-ma. Chin Med J (Engl) 2018; 131(23): 2852‒9.

Choudhari N, Pathak-Ray V, Kaushik S, Vyas P, George R. Prev-alent practice patterns in glaucoma: Poll of Indian ophthal-mologists at a national conference. Indian J Ophthalmol 2016; 64(10): 715–21.

Kalayci M, Cetinkaya E, Erol MK. Prevalence of primary open-angle glaucoma in a Somalia population. Int Ophthalmol 2021; 41(2): 581‒6.

Lee JY, Akiyama G, Saraswathy S, Xie X, Pan X, Hong YK, et al. Aqueous humour outflow imaging: seeing is believing. Eye (Lond) 2021; 35(1): 202‒15.

Camp DA, Yadav P, Dalvin LA, Shields CL. Glaucoma second-ary to intraocular tumors: mechanisms and management. Curr Opin Ophthalmol 2019; 30(2): 71‒81.

Mocan MC, Mehta AA, Aref AA. Update in genetics and surgi-cal management of primary congenital glaucoma. Turk J Oph-thalmol 2019; 49(6): 347‒55.

Zhang N, Wang J, Chen B, Li Y, Jiang B. Prevalence of primary angle closure glaucoma in the last 20 years: A meta-analysis and systematic review. Front Med (Lausanne) 2021; 7: 624179.

Flores-Sánchez BC, Tatham AJ. Acute angle closure glaucoma. Br J Hosp Med (Lond) 2019; 80(12): C174‒9.

Hagiwara Y, Koh JEW, Tan JH, Bhandary SV, Laude A, Ciaccio EJ, et al. Computer-aided diagnosis of glaucoma using fundus images: A review. Comput Methods Programs Biomed 2018; 165: 1‒12.

Storgaard L, Tran TL, Freiberg JC, Hauser AS, Kolko M. Glau-coma clinical research: Trends in treatment strategies and drug development. Front Med (Lausanne) 2021; 8: 733080.

Mangione CM, Lee PP, Gutierrez PR, Spritzer K, Berry S, Hays RD, et al. Development of the 25-item National Eye Institute Visual Function Questionnaire. Arch Ophthalmol 2001; 119(7): 1050‒8.

Kovač B, Vukosavljević M, Djokić Kovač J, Resan M, Trajković G, Janković J, et al. Validation and cross-cultural adaptation of the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) in Serbian patients. Health Qual Life Outcomes 2015; 13: 142.

European Glaucoma Society. Optic nerve head and retinal nerve fibre layer. In: Terminology and guidelines for glaucoma. 5th ed. Br J Ophthalmol 2021; 105(Suppl 1): 71‒81.

Hodapp E, Parrish RK, Anderson DR. Clinical decisions in glau-coma. St. Louis: Mosby; 1993. 204 p.

Machado LF, Kawamuro M, Portela RC, Fares NT, Bergamo V, Souza LM, et al. Factors associated with vision-related quality of life in Brazilian patients with glaucoma. Arq Brass Oftalmol 2019; 82(6): 463‒70.

Ribeiro MV, Hasten-Reiter Júnior HN, Ribeiro EA, Jucá MJ, Bar-bosa FT, Sousa-Rodrigues CF. Association between visual im-pairment and depression in the elderly: a systematic review. Arq Bras Oftalmol 2015; 78(3): 197–201.

Courtney-Long EA, Carroll DD, Zhang QC, Stevens AC, Griffin-Blake S, Armour BS, et al. Prevalence of Disability and Disa-bility Type Among Adults--United States, 2013. MMWR Morb Mortal Wkly Rep 2015; 64(29): 777–83.

Biggerstaff KS, Lin A. Glaucoma and Quality of Life. Int Oph-thalmol Clin 2018; 58(3): 11‒22.

Shin DY, Jung KI, Park HY, Park CK. The effect of anxiety and depression on progression of glaucoma. Sci Rep 2021; 11(1): 1769.

Tharmathurai S, Muhammad-Ikmal MK, Razak AA, Che-Hamzah J, Azhany Y, Fazilawati Q, et al. Depression and Severity of Glaucoma Among Older Adults in Urban and Suburban Are-as. J Glaucoma 2021; 30(5): e205‒12.

Hirneiss C, Kortüm K. Quality of Life in Patients with Glauco-ma. Klin Monbl Augenheilkd 2016; 233(2): 148‒53. (Ger-man)

Stein JD, Khawaja AP, Weizer JS. Glaucoma in Adults-Screening, Diagnosis, and Management: A Review. JAMA 2021; 325(2): 164‒74.

Tanito M, Matsuoka Y. Proportion of Glaucoma Types and Surgeries Among Young, Pre-Old, Old, and Oldest-Old Age Groups or Different Sex Groups. Clin Ophthalmol 2022; 16: 1815‒9.

Tekin K, Inanc M, Elgin U. Monitoring and management of the patient with pseudoexfoliation syndrome: current perspec-tives. Clin Ophthalmol 2019; 13: 453–64.

McKean-Cowdin R, Varma R, Wu J, Hays RD, Azen SP; Los An-geles Latino Eye Study Group. Severity of visual field loss and health-related quality of life. Am J Ophthalmol 2007; 143(6): 1013–23.

Wolfram C, Lorenz K, Breitscheidel L, Verboven Y, Pfeiffer N. Health- and vision-related quality of life in patients with ocu-lar hypertension or primary open-angle glaucoma. Ophthalmo-logica 2013; 229(4): 227–34.

Šarenac-Vulović T, Pavlović S, Janicijević K, Todorović D, Paunović S, Petrović N, et al. Tear film stability in patients with pseudoex-foliation. Ser J Exp Clin Res 2018; 19(3): 243‒6.

Zhang X, Vadoothker S, Munir WM, Saeedi O. Ocular Surface Disease and Glaucoma Medications: A Clinical Approach. Eye Contact Lens 2019; 45(1): 11‒8.

Todorović D, Šarenac-Vulovic T, Jovanović S, Janićijević-Petrović M, Petrović N, Kontić M, et al. The impact of pseudoexfoliation and artificial tear application on the tear film stability in a pseudo-phakic eye. Srp Arh Celok Lek 2018; 146(7¬¬¬¬-8): 422‒7.

Dermenoudi M, Matsou A, Keskini C, Anastasopoulos E. Ocular Surface Disease Signs and Symptoms in Patients with Pseudo-exfoliative Glaucoma: A Case-Control Study. Vision (Basel) 2022; 6(1): 11.

Rao A, Raj N, Pradhan A, Senthil S, Garudadri CS, Verma PVKS, et al. Visual impairment in pseudoexfoliation from four tertiary centres in India. PLoS One 2020; 15(5): e0233268.

Singh VM, Yerramneni R, Madia T, Prashanthi S, Vaddavalli PK, Reddy JC. Complications and visual outcomes of cataract sur-gery in patients with pseudoexfoliation. Int Ophthalmol 2021; 41(7): 2303‒14.

Cho YK, Huang W, Nishimura E. Myopic refractive shift repre-sents dense nuclear sclerosis and thin lens in lenticular myopia. Clin Exp Optom 2013; 96(5): 479‒85.

Montana CL, Bhorade AM. Glaucoma and quality of life: fall and driving risk. Curr Opin Ophthalmol 2018; 29(2): 135‒40.

Jin S, Trope GE, Buys YM, Badley EM, Thavorn K, Yan P, et al. Reduced social participation among seniors with self-reported visual impairment and glaucoma. PLoS One 2019; 14(7): e0218540.

E JY, Schrack JA, Mihailovic A, Wanigatunga AA, West SK, Friedman DS, et al. Patterns of Daily Physical Activity across the Spectrum of Visual Field Damage in Glaucoma Patients. Ophthalmology 2021; 128(1): 70‒7.

Mabuchi F, Yoshimura K, Kashiwagi K, Shioe K, Yamagata Z, Kanba S, et al. High prevalence of anxiety and depression in patients with primary open-angle glaucoma. J Glaucoma 2008; 17(7): 552–7.

Tastan S, Iyigun E, Bayer A, Acikel C. Anxiety, depression, and quality of life in Turkish patients with glaucoma. Psychol Rep 2010; 106(2): 343–57.

Zhou C, Qian S, Wu P, Qiu C. Anxiety and depression in Chi-nese patients with glaucoma: sociodemographic, clinical, and self-reported correlates. J Psychosom Res 2013; 75(1): 72–82.

Zhang X, Olson DJ, Le P, Lin FC, Fleischman D, Davis RM. The association between glaucoma, anxiety, and depression in a large population. Am J Ophthalmol 2017; 183: 37–41.

Nelson P, Aspinall P, Papasouliotis O, Worton B, O'Brien C. Qual-ity of life in glaucoma and its relationship with visual func-tion. J Glaucoma 2003; 12(2): 139‒50.

Skalicky SE, Fenwick E, Martin KR, Crowston J, Goldberg I, McCluskey P. Impact of age-related macular degeneration in patients with glaucoma: understanding the patients' perspec-tive. Clin Exp Ophthalmol 2016; 44(5): 377‒87.

Wilson MR, Coleman AL, Yu F, Sasaki I, Bing EG, Kim MH. Depression in patients with glaucoma as measured by self-report surveys. Ophthalmology 2002; 109(5): 1018‒22.

Onakoya AO, Mbadugha CA, Aribaba OT, Ibidapo OO. Quality of life of primary open angle glaucoma patients in lagos, Nige-ria: clinical and sociodemographic correlates. J Glaucoma 2012; 21(5): 287–95.

Marčeta E, Todorovic D. The effect of glaucoma on the quality of patient’s life. Ser J Exp Clin Res 2021. doi: 10.2478/sjecr-2020-0046.

Kvalitet života bolesnika sa primarnim glaukomom otvorenog ugla, primarnim glaukomom zatvorenog ugla i pseudoeksfolijativnim glaukomom u centralnoj Srbiji

Sažetak

Reference