Bifurkacije u kontekstu PKI HTO – uvid u registar HTO jednog centra u Beogradu

  • Stefan Juričić University Clinical Center of Serbia, Clinic for Cardiology, Belgrade, Serbia
  • Milorad Tešić University Clinical Center of Serbia, Clinic for Cardiology, Belgrade, Serbia
  • Milan Dobrić University of Belgrade, Faculty of Medicine, Belgrade, Serbia
  • Siniša Stojković University Clinical Center of Serbia, Clinic for Cardiology, Belgrade, Serbia
Ključne reči: angiografija koronarnih arterija, koronarna okluzija, perkutana koronarna intervencija, stentovi

Sažetak


Uvod/Cilj. Hronične totalne okluzije (HTO) koronarnih arterija su i dalje među najsloženijim procedurama u lečenju koronarnih arterija. Ukoliko postoji bifurkaciona lezija u sklopu HTO, to je jedan od najvećih izazova za interventne kardiologe. Metode. Prikazujemo restrospektivnu analizu bolesnika lečenih u našem centru, kojima je rađena perkutana koronarna intervencija (PKI) sa bifurkacionom lezijom unutar HTO i bočnom granom dijametra 2 mm ili više, od januara 2017. do decembra 2020. godine. Rezultati. Od ukupno 216 bolesnika lečenih u četvorogodišnjem periodu, 38 (18%) ih je imalo bifurkacionu leziju u sklopu HTO. Najčešće bifurkacione lezije (50%) bile su na prednjoj descendentnoj koronarnoj arteriji, a najređe (21%) na cirkumfleksnoj koronarnoj arteriji. Uspešna rekanalizacija HTO ostvarena je kod 35 (92%) bolesnika. Tehnika jednim stentom korišćena je kod 27 (77%) bolesnika, dok je tehnika sa dva stenta korišćena kod 8 (23%) bolesnika. Zaključak. Bifurkacione lezije u kontekstu PKI HTO su relativno čest nalaz na koronarografiji i predstavljaju poseban izazov za HTO operatore. Provisional tehnika (tehnika jednim stentom) najčešća je strategija lečenja bifurkacionih lezija i kod bolesnika sa HTO.

Reference

1.      Galassi AR, Sianos G, Werner GS, Escaned J, Tomasello SD, Boukhris M, et al. Retrograde recanalization of chronic total occlusions in Europe: Procedural, in-hospital, and long-term outcomes from the multicenter ERCTO registry. J Am Coll Cardiol 2015; 65(22): 2388–400.

2.      Brilakis ES, Banerjee S, Karmpaliotis D, Lombardi WL, Tsai TT, Shunk KA, et al. Procedural outcomes of chronic total occlusion percutaneous coronary intervention: A report from the NCDR (National Cardiovascular Data Registry). JACC Cardiovasc Interv 2015; 8(2): 245–53.

3.      Juricic SA, Tesic MB, Galassi AR, Petrovic ON, Dobric MR, Orlic DN, et al. Randomized controlled comparison of optimal medical therapy with percutaneous recanalization of chronic total occlusion (COMET-CTO). Int Heart J 2021; 62(1): 16–22.

4.      Werner GS, Martin-Yuste V, Hildick-Smith D, Boudou N, Sianos G, Gelev V, et al. A randomized multicentre trial to compare revascularization with optimal medical therapy for the treatment of chronic total coronary occlusions. Eur Heart J 2018; 39(26): 2484–93.

5.      Stojkovic S, Juricic S, Dobric M, Nedeljkovic MA, Vukcevic V, Orlic D, et al. Improved Propensity-Score Matched Long-Term Clinical Outcomes in Patients with Successful Percutaneous Coronary Interventions of Coronary Chronic Total Occlusion. Int Heart J 2018; 59(4): 719–26.

6.      Lee SW, Lee PH, Ahn JM, Park DW, Yun SC, Han S, et al. Randomized Trial Evaluating Percutaneous Coronary Intervention for the Treatment of Chronic Total Occlusion: The DECISION-CTO Trial. Circulation 2019; 139(14): 1674–83.

7.      Megaly M, Saad M, Tajti P, Burke MN, Chavez I, Gössl M, et al. Meta-analysis of the impact of successful chronic total occlusion percutaneous coronary intervention on left ventricular systolic function and reverse remodeling. J Interv Cardiol 2018; 31(5): 562–71.

8.      Henriques JPS, Hoebers LP, Råmunddal T, Laanmets P, Eriksen E, Bax M, et al. Percutaneous Intervention for Concurrent Chronic Total Occlusions in Patients With STEMI: The EXPLORE Trial. J Am Coll Cardiol 2016; 68(15): 1622–32.

9.      Juricic SA, Stojkovic SM, Galassi AR, Stankovic GR, Orlic DN, Vukcevic VD, et al. Long-term follow-up of patients with chronic total coronary artery occlusion previously randomized to treatment with optimal drug therapy or percutaneous revascularization of chronic total occlusion (COMET-CTO). Front Cardiovasc Med 2023; 9: 1014664.

10.   Juricic S, Tesic M, Dobric M, Aleksandric S, Mehmedbegovic Z, Stankovic G, et al. The retrograde technique for recanalization of chronically occluded coronary arteries: Case series report. Vojnosanit Pregl 2022; 79(5): 503–9.

11.   Bennett J, Dubois C. Coronary bifurcation lesions: is less more? J Thorac Dis 2016; 8(10): E1351–4.

12.   Ojeda S, Pan M, Gutiérrez A, Romero M, Chavarría J, de Lezo JS, et al. Bifurcation lesions involved in the recanalization process of coronary chronic total occlusions: Incidence, treatment and clinical implications. Int J Cardiol 2017; 230: 432–8.

13.   Galassi AR, Boukhris M, Tomasello SD, Marzà F, Azzarelli S, Giubilato S, et al. Incidence, treatment, and in-hospital outcome of bifurcation lesions in patients undergoing percutaneous coronary interventions for chronic total occlusions. Coron Artery Dis 2015; 26(2): 142–9.

14.   Ojeda S, Azzalini L, Chavarría J, Serra A, Hidalgo F, Benincasa S, et al. One Versus 2-stent Strategy for the Treatment of Bifurcation Lesions in the Context of a Coronary Chronic Total Occlusion. A Multicenter Registry. Rev Esp Cardiol 2018; 71(6): 432–9.

15.   Galassi AR, Werner GS, Boukhris M, Azzalini L, Mashayekhi K, Carlino M, et al. Percutaneous recanalisation of chronic total occlusions: 2019 consensus document from the EuroCTO Club. EuroIntervention 2019; 15(2): 198–208.

16.   Chen SL, Ye F, Zhang JJ, Kan J, Lin S, Liu ZZ, et al. Clinical outcomes after recanalization of a chronic total occluded vessel with bifurcation lesions: Results from single-center, prospective, chronic total occlusion registry study. Chin Med J (Engl) 2012; 125(6): 1035–40.

17.   Nikolakopoulos I, Vemmou E, Karacsonyi J, Alaswad K, Karmpaliotis D, Abi Rafeh N, et al. Percutaneous coronary intervention of chronic total occlusions involving a bifurcation: Insights from the PROGRESS-CTO registry. Hell J Cardiol 2022; 66: 80–3.

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2023/08/28
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