Antivirusni i antibakterijski filteri za maske za lice na bazi srebrnih kvantnih tačaka

  • Vukoman Jokanović University of Belgrade, National Institute of the Republic of Serbia, Institute of Nuclear Sciences “Vinča”, Belgrade, Serbia ALBOS doo, Belgrade, Serbia
  • Nemanja Zdravković Scientific Veterinary Institute of Serbia, Belgrade, Serbia
  • Božana Petrović University of Belgrade, *National Institute of the Republic of Serbia, Institute of Nuclear Sciences “Vinča”, Belgrade, Serbia
  • Marija Živković University of Belgrade, Faculty of Dental Medicine, Clinic of Orthodontics, Belgrade, Serbia
  • Vladimir Biočanin University Business Academy in Novi Sad, Faculty of Stomatology in Pančevo, Pančevo, Serbia
  • Ema Aleksić University Business Academy in Novi Sad, Faculty of Stomatology in Pančevo, Pančevo, Serbia
  • Jovana Milutinović University Business Academy in Novi Sad, Faculty of Stomatology in Pančevo, Pančevo, Serbia
  • Tamaš Petrović Scientific Veterinary Institute “Novi Sad”, Novi Sad, Serbia
Ključne reči: filteri;, maske, hirurške;, polimeraza, reakcija stvaranja lanaca;, sars-cov-2;, srebro;, staphylococcus aureus

Sažetak


Pozadina/cilj. Dostupne maske za lice, koje se koriste za zaštitu respiratornog sistema od različitih vrsta patogena, pokazuju nezadovoljavajuću efikasnost, jer je veličina virusa poput SARS-CoV-2 mnogo manja od pora u ovim maskama. Teško disanje kroz neke maske brzo dovodi do zamora, zbog čega obični ljudi izbegavaju da ih nose. Ove činjenice sugerišu da je poželjna potpuno nova strategija u dizajniranju zaštitnih maski za lice. U ovom radu je predstavljeno novo rešenje, adekvatno za zaštitu ljudi izloženih visokoj koncentraciji bakterija i virusa, posebno SARS-CoV-2. Metode. Filteri za ove maske su izrađeni od guste pamučne tkanine impregnirane srebrnim kvantnim tačkama. Filteri su okarakterisani skenirajućom elektronskom mikroskopijom i jonsko spregnutom plazma masenom spektrometrijom. Svojstva vlaženja određivana su merenjem kontaktnih uglova sa vodom, a ispitana je i postojanost boje ovih filtera. Antibakterijski test je izveden korišćenjem Staphilococcus aureus. Test viabilnosti qPCR – test integriteta virusa i RT-qPCR test su korišćeni za procenu antivirusne aktivnosti. Rezultati. In vitro testovi su pokazali izuzetno visoku efikasnost ovih filtera u uništavanju bakterije Staphilococcus aureus i virusa SARS-CoV-2. Filteri su takođe pokazali visoku sigurnost i lako disanje. Zaključak. Visoka efikasnost ovih maski protiv SARS-CoV-2 dokazana je brojnim testovima i one su, po prvi put u svetu, odobrene kao anti-SARS-CoV-2 maske. U međuvremenu, ovo rešenje je primenjeno u praksi, a podaci dobijeni od kupaca su veoma ohrabrujući.

Reference

Rai M, Bonde S, Yadav A, Bhowmik A, Rathod S, Ingle P, et al. Nanotechnology as a Shield against COVID-19: Current Advancement and Limitations. Viruses 2021; 13(7): 1224.

Jokanović V, Živković M, Zdravković N. A new approach to extraordinary efficient protection against COVID 19 based on nanotechnology. Stomatol Glas Srb 2020; 67(2): 100–9.

MacIntyre CR, Seale H, Dung TC, Hien NT, Nga PT, Chughtai AA, et al. A cluster randomised trial of cloth masks compared with medical masks in healthcare workers. BMJ Open 2015; 5(4): e006577.

Leung NHL, Chu DKW, Shiu EYC, Chan KH, McDevitt JJ, Hau BJP, et al. Respiratory virus shedding in exhaled breath and efficacy of face masks. Nat Med 2020; 26(5): 676–80. Erratum in: Nat Med 2020; 26(6): 981.

Shi J, Zou Y, Wang JX, Zeng XF, Chu GW, Sun BC, et al. Investigation on Designing Meltblown Fibers for the Filtering Layer of a Mask by Cross-Scale Simulations. Ind Eng Chem Res 2021; 60(4): 1962–71.

MacIntyre CR, Chughtai AA. A rapid systematic review of the efficacy of face masks and respirators against coronaviruses and other respiratory transmissible viruses for the community, healthcare workers and sick patients. Int J Nurs Stud 2020; 108: 103629.

He J, Zhao H, Li X, Su D, Zhang F, Ji H, et al. Superelastic and superhydrophobic bacterial cellulose/silica aerogels with hierarchical cellular structure for oil absorption and recovery. J Hazard Mater 2018; 346: 199–207.

Xuao FX, Pagliaro M, Xu YJ, Liu B. Layer-by-layer assembly of versatile nanoarchitectures with diverse dimensionality: a new perspective for rational construction of multilayer assemblies. Chem Soc Rev 2016; 45(11): 3088–121.

Emam HE, Mowafi S, Mashaly HM, Rehan M. Production of antibacterial colored viscose fibers using in situ prepared spherical Ag nanoparticles. Carbohydr Polym 2014; 110: 148–55.

Chakraborty D, Kumar S, Chandrasekaran N, Mukherjee A. Viral Diagnostics and Preventive Techniques in the Era of COVID-19: Role of Nanoparticles. Front Nanotechnol 2020; 2: 588795.

Wei DW, Wei H, Gauthier AC, Song J, Jin Y, Xiao H. Superhydrophobic modification of cellulose and cotton textiles: Methodologies and applications. J Biores Bioprod 2020; 5(1): 1–15.

Wyszogrodzka G, Marszałek B, Gil B, Dorożyński P. Metal-organic frameworks: mechanisms of antibacterial action and potential applications. Drug Discov Today 2016; 21(6): 1009–18.

Black JG. Microbiology: principles and applications. 3rd ed. Upper Saddle River, NJ: Prentice Hall; 1996. 880 p.

Rodríguez RA, Pepper IL, Gerba CP. Application of PCR-based methods to assess the infectivity of enteric viruses in environmental samples. Appl Environ Microbiol 2009; 75(2): 297–307.

Huntley CJ, Crews KD, Curry ML. Chemical Functionalization and Characterization of Cellulose Extracted from Wheat Straw Using Acid Hydrolysis Methodologies. Int J Polym Sci 2015; (11): 1–9.

Smiechowicz E, Niekraszewicz B, Kulpinski P. Optimisation of AgNP Synthesis in the Production and Modification of Antibacterial Cellulose Fibres. Materials (Basel) 2021; 14(15): 4126.

Fuster N, Pintó RM, Fuentes C, Beguiristain N, Bosch A, Guix S. Propidium monoazide RTqPCR assays for the assessment of hepatitis A inactivation and for a better estimation of the health risk of contaminated waters. Water Res 2016; 101: 226–32.

Shah SR, Kane SR, Elsheikh M, Alfaro TM. Development of a rapid viability RT-PCR (RV-RT-PCR) method to detect in-fectious SARS-CoV-2 from swabs. J Virol Methods 2021; 297: 114251.

Wurtzer S, Waldman P, Ferrier-Rembert A, Frenois-Veyrat G, Mouchel JM, Boni M, et al. Several forms of SARS-CoV-2 RNA can be detected in wastewaters: Implication for wastewater-based epidemiology and risk assessment. Water Res 2021; 198: 117183.

Polo D, Lois M, Fernández-Núñez MT, Romalde JL. Detection of SARS-CoV-2 RNA in bivalve mollusks and marine sediments. Sci Total Environ 2021; 786: 147534.

Cangelosi GA, Meschke JS. Dead or alive: molecular assessment of microbial viability. Appl Environ Microbiol 2014; 80(19): 5884–91.

Corman VM, Landt O, Kaiser M, Molenkamp R, Meijer A, Chu DK, et al. Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Euro Surveill 2020; 25(3): 2000045. Erratum in: Euro Surveill 2020; 25(14): 20200409c. Erratum in: Euro Surveill 2020; 25(30): 2007303. Erratum in: Euro Surveill 2021; 26(5): 210204e.

Tang YW, Stratton CW. Staphylococcus aureus: An old pathogen with new weapons. Clin Lab Med 2010; 30(1): 179–208.

Miller LG, Kaplan SL. Staphylococcus aureus: A community pathogen. Infect Dis Clin North Am 2009; 23(1): 35–52.

Payne SC, Benninger MS. Staphylococcus aureus is a major pathogen in acute bacterial rhinosinusitis: a meta-analysis. Clin Infect Dis 2007; 45(10): e121–7.

Kaplan SL, Hulten KG, Gonzalez BE, Hammerman WA, Lamberth L, Versalovic J, et al. Three-year surveillance of community-acquired Staphylococcus aureus infections in children. Clin Infect Dis 2005; 40(12): 1785–91.

Savić Radovanović R, Zdravković N, Velebit B. Occurrence and Characterization of Enterotoxigenic Staphylococci Isolated from Soft Cheeses in Serbia. Acta Vet 2020; 70(2): 238–54.

Goggin R, Jardeleza C, Wormald PJ, Vreugde S. Colloidal silver: a novel treatment for Staphylococcus aureus biofilms? Int Forum Allergy Rhinol 2014; 4(3): 171–5.

Grigor'eva A, Saranina I, Tikunova N, Safonov A, Timoshenko N, Rebrov A, et al. Fine mechanisms of the interaction of silver nanoparticles with the cells of Salmonella typhimurium and Staphylococcus aureus. Biometals 2013; 26(3): 479–88.

Deng X, Nikiforov AY, Coenye T, Cools P, Aziz G, Morent R, et al. Antimicrobial nano-silver non-woven polyethylene terephthalate fabric via an atmospheric pressure plasma deposition process. Sci Rep 2015; 5: 10138.

Jia M, Chen Z, Guo Y, Chen X, Zhao X. Efficacy of silk fibroin–nano silver against Staphylococcus aureus biofilms in a rabbit model of sinusitis. Int J Nanomedicine 2017; 12: 2933–9.

Peroja KAG, Tuberon NAL, Garcia KA. A review of metal nanoparticles incorporated in polymer matrices for water disinfection. Global Sci J 2019; 7(2): 264–311.

Mackay IM, Arden KE, Nitsche A. Real-time PCR in virology. Nucleic Acids Res 2002; 30(6): 1292–305.

Kageyama T, Kojima S, Shinohara M, Uchida K, Fukushi S, Hoshino FB, et al. Broadly reactive and highly sensitive assay for Norwalk-like viruses based on real-time quantitative reverse transcription-PCR. J Clin Microbiol 2013; 41(4): 1548–57.

Leifels M, Cheng D, Sozzi E, Shoults DC, Wuertz S, Mongkolsuk S, et al. Capsid integrity quantitative PCR to determine virus infectivity in environmental and food applications - A systematic review. Water Res X 2020; 11: 100080.

Blanco A, Guix S, Fuster N, Fuentes C, Bartolomé R, Cornejo T, et al. Norovirus in Bottled Water Associated with Gastroenteritis Outbreak, Spain, 2016. Emerg Infect Dis 2017; 23(9): 1531–4. Erratum in: Emerg Infect Dis 2017; 23(11): 1937.

Randazzo W, Khezri M, Ollivier J, Le Guyader FS, Rodríguez-Díaz J, Aznar R, et al. Optimization of PMAxx pretreatment to distinguish between human norovirus with intact and altered capsids in shellfish and sewage samples. Int J Food Microbiol 2008; 266: 1–7.

Terio V, Lorusso V, Mottola A, Buonavoglia C, Tantillo G, Bonerba E, et al. Norovirus Detection in Ready-To-Eat Salads by Propidium Monoazide Real Time RT-PCR Assay. Appl Sci 2020; 10(15): 5176.

Čolović B, Kisić D, Jokanović B, Rakočević Z, Nasov I, Trajkovska Petkovska A, et al. Wetting properties of titanium oxides, oxynitrides and nitrides obtained by DC and pulsed magnetron sputtering and cathodic arc evaporation. Mater Sci Pol 2019; 37(2): 173–81.

Parvate S, Dixit P, Chattopadhyay S. Superhydrophobic Surfaces: Insights from Theory and Experiment. J Phy Chem B 2020; 124(8): 1323–60.

Montazer M, Alimohammadi F, Shamei A, Rahimi MK. Durable antibacterial and cross-linking cotton with colloidal silver nanoparticles and butane tetracarboxyl ic acid without yellowing. Colloids Surf B Biointerfaces 2012; 89: 196–202.

Hameed S, Hussain MA, Masood R, Haseeb MT. Cross-linking of cotton fabric using maleic anhydride and sodium hypophosphite. Cellul Chem Technol 2016; 50(2): 321–8.

Kumar TVC, Prasad TNVK, Adilaxmamma K, Alpharaj M, Muralidhar Y, Prasad PE. Novel synthesis of nanosilver particles using plant active principle aloin and evaluation of their cytotoxic effect against Staphylococcus aureus. Asian Pac J Trop Dis 2014; 4(Suppl 1): S92–6.

Thanh NVK, Phong NTP. Investigation of antibacterial activity of cotton fabric incorporating nano silver colloid. J Phys Conf Ser 2009; 187(1): 012072.

Emam HE, Manian AP, Široká B, Duelli H, Redl B, Pipal A, et al. Treatments to impart antimicrobial activity to clothing and household cellulosic-textiles - why “Nano”-silver? J Clean Prod 2013; 39(4): 17–23.

Deng X, Nikiforov A, Vujosevic D, Vuksanovic V, Mugoša B, Cvelbar U, et al. Antibacterial activity of nano-silver non-woven fabric prepared by atmospheric pressure plasma deposition. Mat Lett 2015; 149: 95–9.

Sadeghi B, Garmaroudi FS, Hashemi M, Nezhad HR, Nasrollahi A, Ardalan S, et al. Comparison of the anti-bacterial activity on the nanosilver shapes: Nanoparticles, nanorods and nanoplates. Adv Powder Technol 2012; 23(1): 22–6.

Objavljeno
2024/05/31
Rubrika
Originalni članak