Mentalno zdravlje i kvalitet života žena koje su preživele karcinom dojke u jugoistočnoj Srbiji
Sažetak
Uvod/Cilj. Kvalitet života (KŽ) je jedna od mera ishoda za bolesnike sa hroničnim bolestima. Problemi mentalnog zdravlja često utiču na KŽ bolesnika obolelih od karcinoma. Bolesnici oboleli od karcinoma koji imaju dobar KŽ imaju duži životni vek i sposobni su da vode produktivniji i društveniji život. Cilj rada bio je da se utvrde povezanost mentalnog zdravlja i KŽ i prediktori KŽ kod obolelih od karcinoma dojke (KD). Metode. U istraživanje je uključeno 118 bolesnica koje su lečene na specijalizovanom Odeljenju za karcinom dojke Klinike za onkologiju Univerzitetskog kliničkog centra Niš, Srbija. Kriterijumi za uključivanje u studiju bili su prisustvo nemetastatskog KD u ranoj fazi i završeno hirurško lečenje. Korišćeni su sledeći upitnici: opšti socijalno demografski upitnik, Bolnička skala za procenu anksioznosti i depresije (Hospital Anxiety and Depression Scale - HADS), Bas-Perijev Upitnik agresije (Buss-Perry Aggression Questionnaire), Upitnik o ranim maladaptivnim šemama – skraćena verzija (Early Maladaptive Schema Questionnaire-Short Form – SQ-SF), Flanaganova Skala za procenu kvaliteta života (Flanagan’s Quality of Life Scale – QoLS), Holms-Raheova skala stresa (Holmes and Rahe Stress Scale), Berlinska skala so-cijalne podrške (Berlin Social Support Scales – BSSS), Zdravstveni lokus kontrole (Health Locus of Control). Rezultati. Utvrđena je statistički značajna negativna korelacija sa emocionalnim stanjem, odnosno skorom anksioznosti, skorom depresivnosti, ukupnim skorom stresa i skorom fizičke agresije, dok je KŽ pozitivno korelisao sa svim subskalama upitnika percipirane socijalne podrške (PSP). Značajno drugačiji KŽ imale su bolesnice sa sledećim ranim maladaptabilnim shemama: emocionalna deprivacija, emocionalna inhibicija i osećaj za pravo/narcizam. Takođe, KŽ se značajno razlikovao u zavisnosti od partnerskog statusa, prisustva klinički značajne anksioznosti, prisustva hormon-senzitivnih karcinoma, prisustva human epidermal growth factor receptor 2 (HER2)-pozitivnog karcinoma i vremena od postavljanja dijagnoze. Urađena je višestruka linearna regresija, a najveći udeo imale su depresivnost i PSP. Zaključak. U našoj studiji, prisustvo depresivnosti i PSP bili su najbolji prediktori KŽ žena koje su preživele KD.
Reference
International Agency for Research on Cancer. Cancer Today [Inter-net]. France IARC; 2024 [cited 2024 Mar 22; accessed on 2024 June 10]. Available from: https://gco.iarc.fr/today/en
Dinapoli L, Colloca G, Di Capua B, Valentini V. Psychological aspects to consider in BC diagnosis and treatment. Curr Oncol Rep 2021; 23(3): 38.
İzci F, İlgün AS, Fındıklı E, Özmen V. Psychiatric symptoms and psychosocial problems in patients with BC. J Breast Health 2016; 12(3): 94–101.
Carreira H, Williams R, Dempsey H, Stanway S, Smeeth L, Bhaskaran K. Quality of life and mental health in BC survivors compared with non-cancer controls: a study of patient-reported outcomes in the United Kingdom. J Cancer Surviv 2021; 15(4): 564–75.
Zolfaghary F, MashaghiTabari R, Dezhman M, Bijani A, Kheirkha F, Adib-Rad H. Predictors of quality of life and mental health in BC survivors in Northern Iran. BMC Womens Health 2023; 23(1): 378.
Addington-Hall J, Kalra L. Who should measure quality of life? BMJ 2001; 322(7299): 1417–20.
Hassan BAR. Supportive and palliative care and quality of life in oncology. London: IntechOpen; 2023. 204 p.
Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983; 67(6): 361–70.
Singer S, Kuhnt S, Götze H, Hauss J, Hinz A, Liebmann A, et al. Hospital anxiety and depression scale cutoff scores for cancer patients in acute care. Br J Cancer 2009; 100(6): 908–12.
Buss AH, Perry M. The aggression questionnaire. J Pers Soc Psychol 1992; 63(3): 452–9.
Gerevich J, Bácskai E, Czobor P. The generalizability of the Buss–Perry Aggression Questionnaire. Int J Methods Psychiatr Res 2007; 16(3): 124–36.
Young JE, Brown G. Young Schema Questionnaire Short Form. New York: Cognitive Therapy Center; 1998.
Oettingen J, Chodkiewicz J, Mącik D, Gruszczyńska E. Polish ad-aptation of the young schema questionnaire 3 short form (YSQ-S3-PL). Psychiatr Pol 2018; 52(4): 707–18.
Young JE, Klosko JS, Weishaar ME. Schema therapy: A practi-tioner’s guide. NY: Guilford Press; 2003. 436 p.
Burckhardt CS, Anderson KL, Archenholtz B, Hägg O. The Flana-gan Quality Of Life Scale: evidence of construct validity. Health Qual Life Outcomes 2003; 1(1): 59.
Flanagan JC. Measurement of quality of life: current state of the art. Arch Phys Med Rehabil 1982; 63(2): 56–9.
Burckhardt CS, Woods SL, Schultz AA, Ziebarth DM. Quality of life of adults with chronic illness: A psychometric study. Res Nurs Health 1989; 12(6): 347–54.
Burckhardt CS, Anderson KL. The Quality of Life Scale (QOLS): reliability, validity, and utilization. Health Qual Life Outcomes 2003; 1: 60.
Dantas RAS, Motzer SA, Ciol MA. The relationship between quality of life, sense of coherence and self-esteem in persons after coronary artery bypass graft surgery. Int J Nurs Stud 2002; 39(7): 745–55.
Wallston BS, Wallston KA, Kaplan GD, Maides SA. Develop-ment and validation of the health locus of control (HLC) scale. J Consult Clin Psychol 1976; 44(4): 580–5.
Rahe RH, Biersner RJ, Ryman DH, Arthur RJ. Psychosocial predictors of illness behavior and failure in stressful training. J Health Soc Behav 1972; 13(4): 393–7.
Schulz U, Schwarzer R. Social support in coping with illness: the Berlin Social Support Scales (BSSS). Diagnostica 2003; 49(2): 73–82. (German)
Konieczny M, Cipora E, Sygit K, Fal A. Quality of Life of Wom-en with BC and Socio-Demographic Factors. Asian Pac J Can-cer Prev 2020; 21(1): 185–93.
Brunault P, Champagne AL, Huguet G, Suzanne I, Senon JL, Body G, et al. Major depressive disorder, personality disorders, and coping strategies are independent risk factors for lower quality of life in non‐metastatic BC patients. Psychooncology 2016; 25(5): 513–20.
De Vlaming IH, Schellekens MPJ, van der Lee ML. Intensity of mental health treatment of cancer-related psychopathology: the predictive role of Early Maladaptive Schemas. Support Care Cancer 2023; 31(6): 325.
Katebi H, Kalhornia Golkar M, Ataeefar R. Predicting Quality of Life Based on Early Maladaptive Schemas and Personality Traits in Women with BC. Razavi Int J Med 2021; 9(3): 13–7.
Diržytė A, Milašienė V. Relationship between activated early maladaptive schemas and weakened immune system. Psichologija 2002; 25: 43–51.
Davidson CA, Booth R, Jackson KT, Mantler T. Toxic Relation-ships Described by People With BC on Reddit: Topic Model-ing Study. JMIR cancer 2024; 10(1): e48860.
Yan B, Yang LM, Hao LP, Yang C, Quan L, Wang LH, et al. Determinants of quality of life for BC patients in Shanghai, China. PLoS One 2016; 11(4): e0153714.
Montazeri A. Health-related quality of life in BC patients: A bibliographic review of the literature from 1974 to 2007. J Exp Clin Cancer Res 2008; 27: 1–31.
Schleife H, Sachtleben C, Finck Barboza C, Singer S, Hinz A. Anx-iety, depression, and quality of life in German ambulatory BC patients. BC 2014; 21(2): 208–13.
Antoni MH, Lehman JM, Klibourn KM, Boyers AE, Culver JL, Alferi SM, et al. Cognitive-behavioral stress management in-tervention decreases the prevalence of depression and enhanc-es benefit finding among women under treatment for early-stage BC. Health Psychol 2001; 20(1): 20–32.
Tatrow K, Montgomery GH. Cognitive behavioral therapy tech-niques for distress and pain in BC patients: A meta-analysis. J Behav Med 2006; 29(1): 17–27.
Duijts SFA, Faber MM, Oldenburg HSA, van Beurden M, Aaronson NK. Effectiveness of behavioral techniques and physical exercise on psychosocial functioning and health‐related quality of life in BC patients and survivors—a meta‐analysis. Psychooncology 2011; 20(2): 115–26.
Stagl JM, Antoni MH, Lechner SC, Bouchard LC, Blomberg BB, Glück S, et al. Randomized controlled trial of cognitive behav-ioral stress management in BC: A brief report of effects on 5-year depressive symptoms. Health Psychol 2015; 34(2): 176–80.
Gudenkauf LM, Antoni MH, Stagl JM, Lechner SC, Jutagir DR, Bouchard LC, et al. Brief cognitive–behavioral and relaxation training interventions for BC: A randomized controlled trial. J Consult Clin Psychol 2015; 83(4): 677–88.