Promenljiva slika faktora rizika od cerebralne paralize
Sažetak
Uvod/Cilj. Etiologija cerebralne paralize (CP) je multifaktorijalna i još uvek nije potpuno razjašnjena. Cilj rada bio je da se utvrde promene u etiološkim faktorima CP tokom poslednjih 30 godina. Metode. Retrospektivnom studijom analizirana je baza podataka 296 bolesnika sa CP. Faktori rizika (FR) podeljeni su u prekonceptualne, antenatalne, intrapartalne i neonatalne. Bolesnici u registru podeljeni su u tri kohorte: na bolesnike rođene pre 2000. godine, one rođene između 2000. i 2010. godine i bolesnike rođene posle 2010. godine. Promene u FR od CP istraživane su u intervalima od po deset godina. Rezultati. Najveću učestalost imalo je sledećih pet FR: niska porođajna težina (46,62%), prevremenost (44,25%), životno doba majke iznad 35 godina starosti (37,16%), hitni carski rez (33,78%) i asfiksija pri porođaju (25,33%). Stopa brakova između srodnika iznosila je 22,29%. Zaključak. Stope niske porođajne težine i prevremenost, koji su najčešće označeni FR od CP, postepeno se poboljšavaju. Stopa asfiksije pri porođaju smanjena je u poslednjih deset godina. Stopa ‘odmakla starost majke’ raste, a brak između srodnika i dalje predstavlja važan FR u Turskoj.
Reference
Richards CL, Malouin F. Cerebral palsy: definition, assessment and rehabilitation. Handb Clin Neurol 2013; 111: 183–95.
Johnson A. Prevalence and characteristics of children with cer-ebral palsy in Europe. Dev Med Child Neurol 2002; 44(9): 633–40.
Serdaroğlu A, Cansu A, Ozkan S, Tezcan S. Prevalence of cere-bral palsy in Turkish children between the ages of 2 and 16 years. Dev Med Child Neurol 2006; 48(6): 413–6.
Nelson KB. Causative factors in cerebral palsy. Clin Obstet Gynecol 2008; 51(4): 749–62.
Fahey MC, Maclennan AH, Kretzschmar D, Gecz J, Kruer MC. The genetic basis of cerebral palsy. Dev Med Child Neurol 2017; 59(5): 462–9.
Esih K, Goričar K, Dolžan V, Rener-Primec Z. The association between antioxidant enzyme polymorphisms and cerebral pal-sy after perinatal hypoxic-ischaemic encephalopathy. Eur J Paediatr Neurol 2016; 20(5): 704–8.
Platt MJ, Panteliadis CP, Häusler M. Aetiological Factors. In: Panteliadis CP, editor. Cerebral Palsy: A Multidisciplinary Ap-proach. Cham: Springer International Publishing; 2018. pp. 49–58.
Dammann O. Philosophy, Epidemiology, and Cerebral Palsy Causation. In: Panteliadis CP, editor. Cerebral Palsy. Cham: Springer International Publishing; 2018. pp. 29–33.
Cans C. Surveillance of cerebral palsy in Europe: a collabora-tion of cerebral palsy surveys and registers. Surveillance of Cerebral Palsy in Europe (SCPE). Dev Med Child Neurol 2000; 42(12): 816–24.
McIntyre S, Taitz D, Keogh J, Goldsmith S, Badawi N, Blair E. A systematic review of risk factors for cerebral palsy in children born at term in developed countries. Dev Med Child Neurol 2013; 55(6): 499–508.
Quinn JA, Munoz FM, Gonik B, Frau L, Cutland C, Mallett-Moore T, et al. Preterm birth: Case definition & guidelines for data collection, analysis, and presentation of immunisation safety data. Vaccine 2016; 34(49): 6047–56.
Sellier E, Platt MJ, Andersen GL, Krägeloh-Mann I, De La Cruz J, Cans C. Decreasing prevalence in cerebral palsy: a multi-site European population-based study, 1980 to 2003. Dev Med Child Neurol 2016; 58(1): 85–92.
Oskoui M, Coutinho F, Dykeman J, Jetté N, Pringsheim T. An up-date on the prevalence of cerebral palsy: a systematic review and meta-analysis. Dev Med Child Neurol 2013; 55(6): 509–19. Erratum in: Dev Med Child Neurol 2016; 58(3): 316.
Himpens E, Van den Broeck C, Oostra A, Calders P, Vanhaesebrouck P. Prevalence, type, distribution, and severity of cerebral palsy in relation to gestational age: a meta-analytic review. Dev Med Child Neurol 2008; 50(5): 334–40.
Smithers-Sheedy H, McIntyre S, Gibson C, Meehan E, Scott H, Goldsmith S, et al. A special supplement: findings from the Australian Cerebral Palsy Register, birth years 1993 to 2006. Dev Med Child Neurol 2016; 58 Suppl 2: 5–10.
Allen MC. Neurodevelopmental outcomes of preterm infants. Curr Opin Neurol 2008; 21(2): 123–8.
Tosun A, Gökben S, Serdaroğlu G, Polat M, Tekgül H. Changing views of cerebral palsy over 35 years: the experience of a cen-ter. Turk J Pediatr 2013; 55(1): 8–15.
Erkin G, Delialioglu SU, Ozel S, Culha C, Sirzai H. Risk factors and clinical profiles in Turkish children with cerebral palsy: analysis of 625 cases. Int J Rehabil Res 2008; 31(1): 89–91.
Wu YW, Croen LA, Shah SJ, Newman TB, Najjar DV. Cerebral palsy in a term population: risk factors and neuroimaging find-ings. Pediatrics 2006; 118(2): 690–7.
Morgan C, Fahey M, Roy B, Novak I. Diagnosing cerebral palsy in full-term infants. J Paediatr Child Health 2018; 54(10): 1159–64.
Shadyab AH, Gass ML, Stefanick ML, Waring ME, Macera CA, Gallo LC, et al. Maternal Age at Childbirth and Parity as Pre-dictors of Longevity Among Women in the United States: The Women's Health Initiative. Am J Public Health 2017; 107(1): 113–9.
Tromp M, Ravelli AC, Reitsma JB, Bonsel GJ, Mol BW. Increas-ing maternal age at first pregnancy planning: health outcomes and associated costs. J Epidemiol Community Health 2011; 65(12): 1083–90.
Lampinen R, Vehviläinen-Julkunen K, Kankkunen P. A review of pregnancy in women over 35 years of age. Open Nurs J 2009; 3: 33–8.
Yilmaz Yalçinkaya E, Hüner B, Dinçer Ü, Diraçoğlu D, Aydin R, İçağasioğlu A, et al. Demographic and Clinical Findings of Cer-ebral Palsy Patients in Istanbul: A Multicenter Study. Turk J Phys Med Rehab 2014; 60: 134–8.
Stillbirth Collaborative Research Network Writing Group. Causes of death among stillbirths. JAMA 2011; 306(22): 2459–68.