Debljina dijafragme je povezana sa preživljavanjem kod starijih pacijenata sa povredom grudnog koša
Sažetak
Uvod/Cilj. Debljina dijafragme (DD) povezana je sa starijim životnim dobom i neželjenim ishodima, posebno u teškim stanjima kao što je prolongirana intubacija. Cilj rada bio je da se proceni prognoza kod starijih pacijenata sa povredom grudnog koša (PGK) i da se ispitaju DD i debljina mišića psoasa kao potencijalni prognostički pokazatelji. Metode. Retrospektivna studija je uključivala konsultacije u vezi sa PGK, preuzete iz bolničkih kartona, obavljene između novembra 2015. i januara 2021. godine. Dokumentovani su demografski podaci, karakteristike povreda, mehanizmi povreda, ukupno preživljavanje, itd. Radiološki snimci su ponovo procenjivani u cilju merenja DD i debljine mišića psoasa. Rezultati. Od ukupno 394 pacijenata, 129 je svrstano u populaciju starijih osoba (> 65 godina). Najčešći mehanizam povrede bili su padovi (n = 71), a sledili su ih saobraćajne nesreće pešaka (n = 16). Ukupno preživljavanje svih pacijenata iznosilo je 43,9 ± 3,6 meseci, sa stopom dvogodišnjeg preživljavanja od 82% za starije pacijente. DD je bila značajno veća kod starijih preživelih nego kod preminulih pacijenata (4,0 ± 1,19 mm vs. 3,57 ± 1,0 mm; p = 0,015). Zaključak. Smanjena DD povezana je sa povišenim rizikom od mortaliteta u populaciji starijih osoba. Starije osobe sa PKG i smanjenom DD mogu imati koristi od programa skrininga ranih intervencija usmerenih prema potencijalno doprinosećim faktorima kao što su slabost, recidivi povreda i propušteni skrining na karcinome. Osim toga, DD može služiti kao potencijalni pokazatelj u sklopu sistema bodovanja u proceni rizika.
Reference
Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. Frailty in el-derly people. Lancet 2013; 381(9868): 752–62. Erratum in: Lancet 2013; 382(9901): 1328.
Goodmanson NW, Rosengart MR, Barnato AE, Sperry JL, Peit-zman AB, Marshall GT. Defining geriatric trauma: when does age make a difference? Surgery 2012; 152(4): 668–74; discus-sion 674–5.
Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing 2010; 39(4): 412–23.
Bourassa-Moreau É, Versteeg A, Moskven E, Charest-Morin R, Flexman A, Ailon T, et al. Sarcopenia, but not frailty, predicts early mortality and adverse events after emergent surgery for metastatic disease of the spine. Spine J 2020; 20(1): 22–31.
Zakaria HM, Wilkinson BM, Pennington Z, Saadeh YS, Lau D, Chandra A, et al. Sarcopenia as a Prognostic Factor for 90-Day and Overall Mortality in Patients Undergoing Spine Sur-gery for Metastatic Tumors: A Multicenter Retrospective Co-hort Study. Neurosurgery 2020; 87(5): 1025–36.
Tsubokawa N, Mimura T, Tadokoro K, Yamashita Y. Classifica-tion based on skeletal muscle mass and the severity of lung emphysema impacts on clinical outcomes after anatomical re-section for lung cancer. Jpn J Clin Oncol 2022: 52(8): 917–24. Erratum in: Jpn J Clin Oncol 2022; 52(11): 1358.
Hadda V, Kumar R, Tiwari P, Mittal S, Kalaivani M, Madan K, et al. Decline in diaphragm thickness and clinical outcomes among patients with sepsis. Heart Lung 2021; 50(2): 284–91.
Ufuk F, Çakmak P, Sağtaş E, Herek D, Arslan M, Yağcı AB. Diaphragm thickness measurement in computed tomography: intra-and inter-observer agreement. Istanbul Med J 2019; 20(2): 101–6.
Hamaker ME, Jonker JM, de Rooij SE, Vos AG, Smorenburg CH, van Munster BC. Frailty screening methods for predicting out-come of a comprehensive geriatric assessment in elderly pa-tients with cancer: a systematic review. Lancet Oncol 2012; 13(10): e437–44.
Barbosa-Silva TG, Menezes AM, Bielemann RM, Malmstrom TK, Gonzalez MC, Grupo de Estudos em Composição Corporal e Nu-trição (COCONUT). Enhancing SARC-F: Improving Sarcope-nia Screening in the Clinical Practice. J Am Med Dir Assoc 2016; 17(12): 1136–41.
Umegaki H. Sarcopenia and frailty in older patients with dia-betes mellitus. Geriatr Gerontol Int 2016; 16(3): 293–9.
Bone AE, Hepgul N, Kon S, Maddocks M. Sarcopenia and frailty in chronic respiratory disease. Chron Respir Dis 2017; 14(1): 85–99.
Ferreira AP, Machado MV. Impact of pretransplant frailty and sarcopenia on the post-transplant prognosis of patients with liver cirrhosis: a systematic review. Eur J Gastroenterol Hepa-tol 2021; 33(1S Suppl 1): e883–97.
Husain ZA, Kim AW, Yu JB, Decker RH, Corso CD. Defining the High-Risk Population for Mortality After Resection of Early Stage NSCLC. Clin Lung Cancer 2015; 16(6): e183–7.
Smith CB, Wolf A, Mhango G, Wisnivesky JP. Impact of Surgeon Volume on Outcomes of Older Stage I Lung Cancer Patients Treated via Video-assisted Thoracoscopic Surgery. Semin Thorac Cardiovasc Surg 2017; 29(2): 223–30.
Ezer N, Kale M, Sigel K, Lakha S, Mhango G, Goodman E, et al. Outcomes after Video-assisted Thoracoscopic Lobectomy ver-sus Open Lobectomy for Early-Stage Lung Cancer in Older Adults. Ann Am Thorac Soc 2018; 15(1): 76–82.
Hamaker ME, Bastiaannet E, Evers D, Water Wv, Smorenburg CH, Maartense E, et al. Omission of surgery in elderly patients with early stage breast cancer. Eur J Cancer 2013; 49(3): 545–52.
Koval KJ, Lurie J, Zhou W, Sparks MB, Cantu RV, Sporer SM, et al. Ankle fractures in the elderly: what you get depends on where you live and who you see. J Orthop Trauma 2005; 19(9): 635–9.
Devon KM, Vergara-Fernandez O, Victor JC, McLeod RS. Colo-rectal Cancer Surgery in Elderly Patients: Presentation, Treatment, and Outcomes. Dis Colon Rectum 2009; 52(7): 1272–7.
Torrance AD, Powell SL, Griffiths EA. Emergency surgery in the elderly: challenges and solutions. Open Access Emerg Med 2015; 7: 55–68.
Anastasio AT, Niu S, Kim EJ, Rhee JM. Evaluating Single-Surgeon Bias Toward Recommending Corrective Procedures for Cervical Spondylotic Myelopathy Based on Demographic Factors and Comorbidities in a 484-Patient Cohort. Global Spine J 2021; 11(2): 167–71.
Menotti A, Mulder I, Nissinen A, Giampaoli S, Feskens EJ, Kro-mhout D. Prevalence of morbidity and multimorbidity in el-derly male populations and their impact on 10-year all-cause mortality: The FINE study (Finland, Italy, Netherlands, El-derly). J Clin Epidemiol 2001; 54(7): 680–6.
Lin YP, Huang YH, Lu FH, Wu JS, Chang CJ, Yang YC. Non-leisure time physical activity is an independent predictor of longevity for a Taiwanese elderly population: an eight-year fol-low-up study. BMC Public Health 2011; 11: 428.
Thabet DB, Makhlouf HA, Hasan AA, Mekkawy AI, Ghanem MK. Serial ultrasonographic monitoring of diaphragmatic and mid-upper arm muscle thickness in mechanically ventilated respiratory patients: A single-center observational study. Clin Respir J 2021; 15(1): 11–8.
Sharma A, Karna ST, Tandon M, Pandey CK, Chaturvedi R, Vyas V, et al. Use of ultrasound-guided preoperative diaphragmatic thickness as a predictor of postoperative weaning failure in re-cipients and donors scheduled for living donor liver transplant surgery. Saudi J Anaesth 2018; 12(3): 406–11.
Satış H, Cindil E, Salman RB, Yapar D, Temel E, Demir NB, et al. Diaphragmatic muscle thickness and diaphragmatic func-tion are reduced in patients with systemic lupus erythematosus compared to those with primary Sjögren’s syndrome. Lupus 2020; 29(7): 715–20.
Wang B, Yin Q, Wang YY, Tu Y, Han Y, Gao M, et al. Dia-phragmatic dysfunction associates with dyspnoea, fatigue, and hiccup in haemodialysis patients: a cross-sectional study. Sci Rep 2019; 9(1): 19382.
Laviola M, Priori R, D’Angelo MG, Aliverti A. Assessment of diaphragmatic thickness by ultrasonography in Duchenne muscular dystrophy (DMD) patients. PLoS One 2018; 13(7): e0200582.
Abd El Aziz AA, Elwahsh RA, Abdelaal GA, Abdullah MS, Saad RA. Diaphragmatic assessment in COPD patients by dif-ferent modalities. Egypt J Chest Dis Tuberc 2017; 66(2): 247–50.
Lee GD, Kim HC, Yoo JW, Lee SJ, Cho YJ, Bae K, et al. Com-puted tomography confirms a reduction in diaphragm thick-ness in mechanically ventilated patients. J Crit Care 2016; 33: 47–50.
Yajima T, Arao M, Yajima K, Takahashi H. Usefulness of com-puted tomography-measured psoas muscle thickness per height for predicting mortality in patients undergoing hemodialysis. Sci Rep 2021; 11(1): 19070.
