Anastomozirajući hemangiom bubrega
Sažetak
Uvod. Anastomozirajući hemangiom (AH) bubrega je veoma redak vaskularni tumor. Ovaj tip tumora je tako nazvan zbog njegove jedinstvene histološke strukture, koja podseća na sinusoidne strukture slezine. Može ličiti na maligne neoplazme, kao što je angiosarkom, zbog čega kliničko i radiološko ispitivanje nije dovoljno za tačnu dijagnozu. Prikaz bolesnika. Prikazujemo 39-godišnjeg muškarca, koji je primljen na Kliniku za nefrologiju Vojnomedicinske akademije u Beogradu, Srbija, radi razmatranja transplantacije bubrega od živog srodnika zbog razvoja terminalne bubrežne bolesti. Kao potencijalni donor bubrega određen je otac bolesnika. Tokom pretransplantacijske procene bolesnika, primećena je sumnjiva tumorska lezija u levom bubregu i urađena je multislajsna kompjuterizovana tomografija trbuha i male karlice. Ovim pregledom je u donjem polu levog bubrega otkrivena lobulirana mekotkivna promena, veličine približno 25 × 15 mm. Zbog navedenog nalaza, odlučeno je da se uradi uklanjanje levog bubrega, radi histopatološke potvrde promene. Patohistološkom analizom, dopunjenom imunofenotipizacijom, dijagnostikovan je AH u bubregu. Zaključak. Prikazani slučaj naglašava značaj hitne hirurške resekcije tumorske mase radi potvrde dijagnoze i izbegavanja odlaganja planirane intervencije kod bolesnika kod kojih je planirana transplantacija bubrega.
Reference
Montgomery E, Epstein JI. Anastomosing hemangioma of the genitourinary tract: a lesion mimicking angiosarcoma. Am J Surg Pathol 2009; 33(9): 1364−9.
Omiyale AO. Anastomosing hemangioma of the kidney: a literature review of a rare morphological variant of hemangioma. Ann Transl Med 2015; 3(11): 151.
Brown JG, Folpe AL, Rao P, Lazar AJ, Paner GP, Gupta R, et al. Primary vascular tumors and tumor-like lesions of the kidney: a clinicopathologic analysis of 25 cases. Am J Surg Pathol 2010; 34(7): 942−9.
Wetherell DR, Skene A, Manya K, Manecksha RP, Chan Y, Bolton DM. Anastomosing haemangioma of the kidney: a rare morphological variant of haemangioma characteristic of genitourinary tract location. Pathology 2013; 45(2): 193−6.
Muñoz-Caicedo B, García-Gómez V, Gutiérrez C, Noreña-Rengifo B, Muñoz-Caicedo J. Unraveling Anastomosing Hemangioma: A Case Report. Cureus 2024; 16(3): e55351.
Abboudi H, Tschobotko B, Carr C, DasGupta R. Bilateral renal anastomosing hemangiomas: a tale of two kidneys. J Endourol Case Rep 2017; 3(1): 176−8.
Kryvenko ON, Gupta NS, Meier FA, Lee MW, Epstein JI. Anastomosing hemangioma of the genitourinary system: eight cases in the kidney and ovary with immunohistochemical and ultrastructural analysis. Am J Clin Pathol 2011; 136(3): 450−7.
Ross M, Polcari A, Picken M, Sankary H, Milner J. Anastomosing hemangioma arising from the adrenal gland. Urology 2012; 80(3): e27−8.
Lin J, Bigge J, Ulbright TM, Montgomery E. Anastomosing haemangioma of the liver and gastrointestinal tract: an unusual variant histologically mimicking angiosarcoma. Am J Surg Pathol 2013; 37(11): 1761−5.
Kryvenko ON, Haley SL, Smith SC, Shen SS, Paluru S, Gupta NS, et al. Haemangiomas in kidneys with end-stage renal disease: a novel clinicopathological association. Histopathology 2014; 65(3): 309−18.
Kondo T, Sasa N, Yamada H, Takagi T, Iizuka J, Kobayashi H, et al. Acquired cystic disease-associated renal cell carcinoma is the most common subtype in long-term dialyzed patients: central pathology results according to the 2016 WHO classification in a multi-institutional study. Pathol Int 2018; 68(10): 543−9.
Zhang W, Wang Q, Liu YL, Yu WJ, Liu Y, Zhao H, et al. Anastomosing hemangioma arising from the kidney: a case of slow progression in four years and review of literature. Int J Clin Exp Pathol 2015; 8(2): 2208−13.
Shanbhogue K, Khandelwal A, Hajdu C, Cao W, Surabhi VR, Prasad SR. Anastomosing hemangioma: a current update on clinical, pathological and imaging features. Abdom Radiol (NY) 2022; 47(7): 2335−46.
Tavora F, Montgomery E, Epstein JI. A series of vascular tumors and tumorlike lesions of the bladder. Am J Surg Pathol 2008; 32(8): 1213−9.
Mehta V, Ananthanarayanan V, Antic T, Krausz T, Milner J, Venkataraman G, et al. Primary benign vascular tumors and tumorlike lesions of the kidney: a clinicopathologic analysis of 15 cases. Virchows Arch 2012; 461(6): 669−76.
Cheon PM, Rebello R, Naqvi A, Popovic S, Bonert M, Kapoor A. Anastomosing hemangioma of the kidney: radiologic and pathologic distinctions of a kidney cancer mimic. Curr Oncol 2018; 25(3): e220−3.
Kim CS, Choi SJN, Kim SS, Suh SH, Bae EH, Ma SK, et al. An anastomosing hemangioma mimicking a renal cell carcinoma in a kidney transplant recipient: a case report. BMC Nephrol 2021; 22(1): 262.
Büttner M, Kufer V, Brunner K, Hartmann A, Amann K, Agaimy A. Benign mesenchymal tumours and tumour-like lesions in end-stage renal disease. Histopathology 2013; 62(2): 229−36.
Ip YT, Yuan JQ, Cheung H, Chan JK. Sporadic hemangioblastoma of the kidney: an underrecognized pseudomalignant tumor? Am J Surg Pathol 2010; 34(11): 1695−700.
Al-Ahmadie HA, Yilmaz A, Olgac S, Reuter VE. Glomus tumor of the kidney: a report of 3 cases involving renal parenchyma and review of the literature. Am J Surg Pathol 2007; 31(4): 585−91.