Preliminarno ispitivanje lokalne primene deksametazona posle ekstrakcije zuba – bolja očuvanost rezidualnog alveolarnog grebena?
Sažetak
Uvod/Cilj. Od ključnog značaja je da visina bezubog alveolarnog grebena posle vađenja zuba ostaje što duže na prihvatljivom nivou. Cilj rada bio je da se prikažu preliminarni rezultati efekata lokalne submukozne primene deksametazona na tkiva iz kojih su ekstrahovani zubi radi pripreme alveolarnih tkiva i nosećih tkiva za prihvatanje zubnih proteza. Metode. Kod ukupno 15 pacijenata (11 krezubih i 4 bezuba) dato je od 0.25 mL do 0.5 mL deksametazona per injectionem bukalno i oralno u alveolarne čašice posle komplikovanih ekstrakcija zuba. Rezultati. Zarastanja rana kod svih pacijenata bila su neometana, bez bolova ili lokalnih upala. Zaključak. Deksametazon može biti lokalno dat u oralna tkiva sa ciljem prevencije postekstrakcione upale i izražene resorpcije rezidualnog alveolarnog grebena. Rezultati studije su obećavajući za lečenje pacijenata koji će biti stomatoprotetski rehabilitovani neposredno posle ekstrakcija zuba i ukazuju na to da nema neželjenih efekata prilikom lokalne primene kortikosteroida na tkiva iz kojih su ekstrahovani zubi.
Reference
Alexander RE, Throndson RR. A review of perioperative corti-costeroid use in dentoalveolar surgery. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000; 90(4): 406−15.
Montgomery MT, Hogg JP, Roberts DL, Redding SW. The use of glucocorticosteroids to lessen the inflammatory sequelae following third molar surgery. J Oral Maxillofac Surg 1990; 48(2): 179−87.
Gersema L, Baker K. Use of corticosteroids in oral surgery. J Oral Maxillofac Surg 1992; 50(3): 270−7.
Markovic A, Todorovic Lj. Effectiveness of dexamethasone and low-power laser in minimizing oedema after third molar sur-gery: a clinical trial. Int J Oral Maxillofac Surg 2007; 36(3): 226−9.
Falkenstein E, Tillmann HC, Christ M, Feuring M, Wehling M. Multiple actions of steroid hormones: a focus on rapid, non-genomic effects. Pharmacol Rev 2000; 52(4): 513−56.
Atwood DA. Reduction of residual ridges: a major oral disease entity. J Prosthet Dent 1971; 26(3): 266−79.
Zmyslowska E, Ledzion S, Jedrzejewski K. Factors affecting man-dibular residual ridge resorption in edentulous patients: a pre-liminary report. Folia Morphol (Warsz) 2007; 66(4): 346−52.
Ortman HR. Factors of bone resorption of the residual ridge. J Prosthet Dent 1962; 12(3): 429−40.
Xie Q, Närhi TO, Nevalainen JM, Wolf J, Ainamo A. Oral status and prosthetic factors related to residual ridge resorption in elderly subjects. Acta Odontol Scand 1997; 55(5): 306−13.
Poštić S, Marković D, Krstić M, Rakočević Z, Brković S. Radio-graphic assessment of edentulous residual ridge reductions. Proceedings of the 15th Congress of the BaSS; 2010 April 22−25; Greece, Thessaloniki; 2010.
Zarb GA, Bolender CL, Eckert SE, Jacob RF, Fenton AH, Mericske-Stern R. Prosthodontic treatment for edentulous patients: Complete dentures and implant-supported prostheses. St. Louis: Mosby; 2004.
Maeda Y, Wood WW. Finite element method simulation of bone resorption beneath a complete denture. J Dent Res 1989; 68(9): 1370−3.
Stoll ML, Good J, Sharpe T, Beukelman T, Young D, Waite PD, et al. Intra-articular corticosteroid injections to the temporoman-dibular joints are safe and appear to be effective therapy in children with juvenile idiopathic arthritis. J Oral Maxillofac Surg 2012; 70(8): 1802−7.
ElHag M, Coghlan K, Christmas P, Harvey W, Harris M. The anti-inflammatory effects of dexamethasone and therapeutic ultra-sound in oral surgery. Brit J Oral Maxillofac Surg 1985; 23(1): 17−23.
Assimes TL, Lessard LM. The use of perioperative corticoster-oids in craniomaxillofacial surgery. Plast Reconstruc Surg 1999; 103(1): 313−22.
