Uticaj postoperativne terapije laserom male snage na oseointegraciju samourezujućih implantata u bočnoj regiji gornje vilice: šestonedeljna split-mouth klinička studija

  • Borka Mandić Clinic of Oral Surgery, Faculty of Dental Medicine, University of Belgrade, Belgrade, Serbia
  • Zoran Lazić Clinic of Dental Medicine, Military Medical Academy, Belgrade, Serbia; Faculty of Medicine of the Military Medical Academy, University of Defence, Belgrade, Serbia
  • Aleksa Marković * Clinic of Oral Surgery, School of Dentistry, University of Belgrade, Serbia
  • Bojan Mandić Clinic of Maxillofacial Surgery, Faculty of Dental Medicine, University of Belgrade, Belgrade, Serbia
  • Miška Mandić Department of Orthodontics, Faculty of Dental Medicine, University of Belgrade, Belgrade, Serbia
  • Ana Djinić Clinic of Oral Surgery, Faculty of Dental Medicine, University of Belgrade, Belgrade, Serbia
  • Bojana Miličić Department for Medical Statistics and Informatics,Faculty of Dental Medicine, University of Belgrade, Belgrade, Serbia
DOI: https://doi.org/10.2298/5035
Ključne reči: dental implants||, ||implantati, stomatološki, oral surgical procedures||, ||hirurgija, oralna, procedure, laser therapy, low-level||, ||lečenje laserom male snage, bone regeneration||, ||kost, regeneracija, alkaline phosphatase||, ||alkalna fosfataza, treatment outcome||, ||lečenje, ishod,

Sažetak


Uvod/Cilj. Terapija laserom male snage (TLMS) stimuliše reparatorne sposobnosti kosti utičući na ćelijsku proliferaciju, diferencijaciju i adheziju, i ima potencijal da skrati vreme zarastanja kosti nakon ugradnje implantata. Cilj ove kliničke studije bio je da se ispita uticaj postoperativne primene TLMS na oseointegraciju i rani uspeh ugradnje samourezujućih implantata u kost male gustine. Metode. Prateći split-mouth dizajn, samourezujući implantati (n = 44) ugrađeni su u posteriorne regije gornje vilice 12 pacijenata. Slučajnim izborom, jednoj od strana vilice je dodeljena TLMS (test grupa), dok je druga strana bila placebo (kontrolna grupa). Za TLMS korišćen je galijum-aluminijum-arsenid (GaAlAs) laser (Medicolaser 637, Technoline, Beograd, Srbija) talasne dužine 637 nm, snage 40 mW, neprekidnog režima rada. Tretman laserom male snage sprovodio se neposredno po ugradnji, a zatim svakodnevno, tokom narednih sedam dana. Ukupna zračna doza po tretmanu bila je 6,26 J/cm² po implantatu. Praćeni su stabilnost implantata, aktivnost alkalne fosfataze (ALP) i procenat rane uspešnosti implantatne terapije. Period praćenja bio je šest nedelja. Rezultati. Zračeni implantati imali su veću stabilnost u odnosu na kontrolne tokom celog perioda praćenja, a statistički značajno veća stabilnost bila je u petoj postoperativnoj nedelji (t-test za vezane uzorke, p = 0.030). Razlika u aktivnosti ALP između grupa nije bila statistički značajna ni u jednoj tački posmatranja (t-test za vezane uzorke, p > 0.05). Procenat rane uspešnosti terapije implantatima bio je 100%, bez obzira na primenjenu TLMS. Zaključak. Svakodnevna primena TLMS u prvoj postoperativnoj nedelji nije pokazala značajan uticaj na oseointegraciju samourezujućih implantata u kost male gustine bočne regije gornje vilice. Primena implantata samourezujućeg makrodizajna u kosti male gustine mogla bi predstavljati predvidljivu terapijsku proceduru sa visokim procentom rane uspešnosti, bez obzira na primenjenu TLMS.

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Objavljeno
2015/07/08
Broj časopisa
Vol. 72 Br. 3 (2015)
Rubrika
Originalni članak