Treatment of recurrent aphthous stomatitis by laser therapy:  A systematic review of the literature

Verica Pavlić; Vesna Vujić-Aleksić; Akira Aoki; Lana Nežić

doi:10.2298/5897

Verica Pavlić Department of Periodontology and Oral Medicine, Institute of Dentistry, Banja Luka, Bosnia and Herzegovina
Vesna Vujić-Aleksić The Republic of Srpska Agency for Certification, Accreditation and Quality Improvement in Health Care, Banja Luka, Bosnia and Herzegovina
Akira Aoki Section of Periodontology, Department of Hard Tissue Engineering, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
Lana Nežić Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Banja Luka, Bosnia and Herzegovina

DOI: https://doi.org/10.2298/5897

Ključne reči: laser therapy, low level||, ||laseri male snage, stomatitis aphthous||, ||stomatitis aftozni, recurrence||, ||recidiv, treatment outcome||, ||lečenje, ishod,

Sažetak

Uvod/cilj. Rekurentni aftozni stomatitis (RAS) definisan je multifaktorskim imunološkim zapaljenskim lezijama u usnoj duplji, koje se karakterišu bolnim, recidivirajućim pojedinačnim/multiplim, plitkim, okruglim/ovoidnim ulceracijama sluzokože. Do danas je predstavljen niz protokola o terapijskom zbrinjavanju RAS, ali kako je oboljenje idiopatske etiologije, predložene terapijske opcije su simptomatske, a ne preventivne ili kurativne. Nedavno je laseroterapija predstavljena kao veoma efikasna opcija terapijskog zbrinjavanja RAS. Cilj ovog rada bio je procena efekata laseroterapije u terapijskom zbrinjavanju RAS na osnovu rezultata kliničkih studija objavljenih u recenziranim časopisima. Metode. Analizirani su radovi objavljeni do 31. decembra 2013, dobijeni pretraživanjem Medline/PubMed, Science Direct i Cochrane Library of the Cochrane Collaboration (CENTRAL) online baza podataka, ukucavanjem ključnih riječi: laser i recurrent aphthous stomatitis, laser i aphthous i laser i aphthae. Ukupno 4 originalna naučna rada, koji su zadovoljili sve kriterijume uključenja/isključenja u ovu studiju podvrgnuta su daljoj analizi. Poseban akcent stavljen je na efeke laseroterapije na ublažavanje bola (analgeziju), te na skraćenje dužine trajanja RAS epizode, odnosno na ubrzano zarastanje lezija. Rezultati. Dostupna literatura ukazuje na prednosti korišćenja laseroterapije u zbrinjavanju RAS, i to u neposrednoj analgeziji, te sposobnosti ubrzanja zarastanja rana. Zaključak. Iako podaci iz dostupne literature ukazuju na prednosti upotrebe laseroterapije u zbrinjavanju RAS, ove rezultate trebalo bi interpretirati uz oprez. Naime, različit dizajn kliničkih studija, različiti iradijacijski parametari lasera korišćeni u tim studijama, te veoma mali broj dostupnih studija u kojima su praćeni isti terapijski ishodi, sprečavaju nas da donesemo konačne zaključke o prednostima laseroterapije u lečenju RAS.

Biografije autora

Verica Pavlić, Department of Periodontology and Oral Medicine, Institute of Dentistry, Banja Luka, Bosnia and Herzegovina

Department of Periodontology and Oral Medicine, assistant professor

Akira Aoki, Section of Periodontology, Department of Hard Tissue Engineering, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

Associate professor

Lana Nežić, Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Banja Luka, Bosnia and Herzegovina

Assistant professor

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Lečenje recidivirajućeg aftoznog stomatitisa primenom lasera: sistematski pregled literature

Sažetak

Biografije autora

Reference