Emocionalno reagovanje kod bolesnika nakon cerebrovaskularnog inzulta u čeonom režnju
Sažetak
Uvod/Cilj. Uočena je pojava emocionalnog reagovanja nakon lezija moždanih struktura kod tumora mozga, povreda glave i sl. Cilj našeg rada bio je ispitivanje povezanosti između lezija čeonog lobusa i emocionalnih reakcija kod bolesnika sa moždanim insultom. Metode. Istraživanjem je obuhvaćeno 118 osoba nakon cerebrovaskularnog inzulta. Lokalizacija lezije određivana je na aksijalnim nekontrasnim CT snimcima, a površina i obim lezije primenom AutoCAD 2004 digitalne planimetrije. Psihometrijsko ispitivanje pomoću Hamiltonove skale za anksioznost (HRSA) i depresiju (HRSD) izvođeno je 11–40 dana nakon insulta. Statistička analiza podataka vršena je prostom linearnom
/nelinearnom regresijom, Cox-ovim hazardnim i generalizovanim linearnim modelom. Rezultati. Utvrđena je češća pojava emocionalnih reakcija, tj. anksioznosti, nakon cerebrovaskularnog insulta kod žena (p = 0.024). Utvrđena je negativna korelacija između veličine lezije i intenziteta anksioznog ispoljavanja (Spearman-ov r = -0.297; p = 0.001). Anksioznost je bila češća kod bolesnika sa lezijama čeonog lobusa dominantne hemisfere (interakcija: čeona lezija * motorno-dominantna hemisfera, p = 0.017). Takođe, vrednosti HRSD skorova pokazale su tendenciju manjeg opadanja u slučaju većih lezija čeonog lobusa u odnosu na lezije drugih regiona prosencefalona (interakcija: čeone lezije * površina lezije, p = 0.001). Zaključak. Rezultati našeg istraživanja ukazuju na povezanost između evoluciono mlađih struktura centralnog nervnog sistema i emotivnih reakcija čoveka. U tom smislu potrebno je preduzimanje odgovarajuće rane psihofarmakoterapije kod rizične grupe bolesnika.
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