Zarastanje koštanog defekta nastalog enukleacijom bilateralnih periapikalnih cista sa i bez upotrebe fibrina obogaćenog trombocitima

  • Nemanja Vuković Clinic for oral surgery and implantology, Faculty of Dentistry, University of Business Academy,Pančevo,Serbia
  • Marjan Marjanović Clinic for oral surgery and implantology, Faculty of Dentistry, University of Business Academy,Pančevo,Serbia
  • Bojan Jovičić Clinic for mouth diseases, Faculty of Dentistry, University of Business Academy,Pančevo, Serbia; Clinic of Dentistry, Military Medical Academy, Belgrade, Serbia
  • Ema Aleksić Clinic for orthodontics, Faculty of Dentistry, University of Business Academy, Pančevo, Serbia
  • Katarina Kalevski Clinic for child and preventive stomatology, Faculty of Dentistry, University of Business Academy, Pančevo, Serbia
  • Nenad Borotić Clinic for prosthodontics, Faculty of Dentistry, University of Business Academy, Pančevo, Serbia
  • Djordje Pejanović Clinic for oral surgery and implantology, Faculty of Dentistry, University of Business Academy, Pančevo, Serbia
  • Marko Andjelković Department of Prosthodontics, School of Dental Medicine, University of Belgrade, Belgrade, Serbia
DOI: https://doi.org/10.2298/VSP151221158V
Ključne reči: oral surgical procedures||, ||hirurgija, oralna, procedure, platelet rich plasma||, ||plazma bogata trombocitima, bone regeneration||, ||kost, regeneracija,

Sažetak


Uvod. Inflamatorne periapikalne lezije su posledica širenja infekcije iz kanala korena zuba. Cilj moderne periapikalne hirurgije je uklanjanje lezija u celosti, kako bi se omogićila potpuna restitucija periapikalnog, sa težnjom da se povrati izgubljeno koštano tkivo. Cilj  ovog  prikaza bolesnika bio je da se klinički i radiografski proceni rezultat  zarastanja koštanog defekta nakon uklanjanja  dve velike periapikalne ciste kod iste osobe u isto vreme, koristeći dva različita regenerativna pristupa. Prikaz bolesnika. Kod zdrave, dvadesetjednogodišnje bolesnice dijagnostivane su dve periapikalne ciste gornjeg levog i desnog lateralnog sekutića i indikovano njihovo hirurško uklanjanje. Jedan koštani defekt je popunjen mešavinom serumskog eksudata dobijenog kompresijom plazme obogaćene fibrinom (PRF) ugruška i govedjeg koštanog ksenografta, a zatim prekriven  membranom od PRF. Drugi defekt popunjen je korišćenjem samo hidratisanog govedjeg koštanog ksenografta i prekriven resorptivnom kolagenom membranom. Kliničko i radiografsko ispitivanje izvršeno je sedam meseci posle hirurškog tretmana. Svi klinički i radiografski parametri bili su značajno poboljšani posle tretmana na oba mesta. Međutim, novoformirana kost oko zuba br. 12 imala je veću koštanu gustinu. Zaključak. PRF je značajno ubrzao zarastanje koštanog defekta.

Reference

Chiapasco M, Rossi A, Motta JJ, Crescentini M. Spontaneous bone regeneration after enucleation of large mandibular cysts: A ra-diographic computed analysis of 27 consecutive cases. J Oral Maxillofac Surg 2000; 58(9): 942−8.

Dahlin C, Gottlow J, Linde A, Nyman S. Healing of maxillary and mandibular bone defects using a membrane technique. An ex-perimental study in monkeys. Scand J Plast Reconstr Surg Hand Surg 1990; 24(1): 13−9.

Santamaría J, García AM, Vicente JC, Landa S, López-Arranz JS. Bone regeneration after radicular cyst removal with and with-out guided bone regeneration. Int J Oral Maxillofac Surg 1998; 27(2): 118−20.

Chen CC, Wang HL, Smith F, Glickman GN, Shyr Y, O'Neal RB. Evaluation of a collagen membrane with and without bone grafts in treating periodontal intrabony defects. J Periodontol 1995; 66(10): 838−47.

Agarwal A, Gupta ND. Combination of bone allograft, barrier membrane and doxycycline in the treatment of infrabony peri-odontal defects: A comparative trial. Saudi Dent J 2015; 27(3): 155−60.

Bashutski JD, Wang H. Periodontal and endodontic regenera-tion. J Endod 2009; 35(3): 321−8.

Del Corso M, Toffler M, Dohan Ehrenfest DM. Use of an autolo-gous leukocyte and platelet-rich fibrin (L-PRF) membrane in post-avulsion sites: an overview of Choukroun’s PRF. J Im-plant Adv Clin Dent 2010; 1: 27–35.

Lazić Z, Bubalo M, Petković-Ćurčin A, Duka M, Mihajlović B. Therapeutic use of platelet-rich plasma in oral surgery. Vojno-sanit Pregl 2009; 66(10): 821−5.

Choukroun J, Adda F, Schoeffler C, Vervelle A. Une opportunité en paro-implantologie: Le PRF. Implantodontie 2001; 42: 55–62. (French)

Ettl T, Gosau M, Sader R, Reichert TE. Jaw cysts - filling or no filling after enucleation? A review. J Craniomaxillofac Surg 2012; 40(6): 485−93.

Oliveira MR, Gabrielli MA, Gabrielli MF, Mariano RC, Pereira Filho VA. Do platelet concentrates promote bone regeneration? Literature review. Musculoskelet Regen 2015; 2: e895.

Nair PR, Pajarola G, Schroeder HE. Types and incidence of hu-man periapical lesions obtained with extracted teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996; 81(1): 93−102.

Simonpieri A, Del Corso M, Sammartino G, Dohan Ehrenfest DM. The relevance of Choukroun's platelet-rich fibrin and metronidazole during complex maxillary rehabilitations using bone allograft. Part I: a new grafting protocol. Implant Dent 2009; 18(2): 102−11.

Paromita M, Nag D, Bhunia S. Treatment of periapical lesion with latelet rich fibrin. Indian Med Gazette 2013: 28−33.

Objavljeno
2017/10/27
Broj časopisa
Vol. 74 Br. 10 (2017)
Rubrika
Prikaz bolesnika