Perikoncepcijska primena folne kiseline kod trudnica u Bosni i Hercegovini: studija preseka

  • Jasmina Djedjibegović Univerzitet u Sarajevu-Farmaceutski fakultet, Katedra za farmaceutsku analitiku
  • Lejla Spahić Unverzitet u Sarajevu-Farmaceutski fakultet, Katedra za Farmaceutsku analitiku
  • Aleksandra Marjanović Univerzitet u Sarajevu-Farmaceutski fakultet, Katedra za farmaceutsku analitiku
  • Amila Turalić Univerzitet u Sarajevu-Farmaceutski fakultet, Katedra za farmaceutsku analitiku
  • Aida Lugušić Univerzitet u Sarajevu-Farmaceutski fakultet, Katedra za farmaceutsku analitiku
  • Miroslav Šober Univerzitet u Sarajevu-Farmaceutski fakultet, Katedra za farmaceutsku analitiku
DOI: https://doi.org/10.5937/arhfarm70-26643
Ključne reči: Folna kiselina, Trudnoća, Defekt neuronske cevi, Prevencija, Suplementacija

Sažetak


Redovna suplementacija folnom kiselinom (FA) preporučuje se svim ženama fertilne dobi i trudnicama. Istraživanja pokazuju da je primena ovih preporuka u praksi nezadovoljavajuća. Cilj ove studije preseka je bio ispitati praksu FA suplementacije među trudnicama u Bosni i Hercegovini (BiH) s obzirom na to da takvi podaci trenutno nisu dostupni. Podaci su prikupljeni putem anonimnog elektronskog upitnika, a učešće u anketi je bilo dobrovoljno. U studiju su uključene trudnice poreklom iz BiH i prebivalištem u BiH najmanje poslednjih 5 godina. Neadekvatna prekoncepcijska suplementacija je primećena kod većine ispitanica (82.1%), a samo 26.9% ispitanica je prijavilo suplementaciju tokom kritičnog perioda pre zatvaranja neuronske cevi u ploda. Primenu visokih doza (≥5 mg/day) FA nakon prvog trimestra je uočena kod 9.0% ispitivanih trudnica. Uzrast ispitanica je bila značajno povezana sa adekvatnom FA suplementacijom (OR=1.207, p<0.05). Rezultati istraživanja ukazuju na suboptimalnu perikoncepcijsku suplementaciju u ciljnoj grupi, što je posebno značajno imajući u vidu da je BiH srednje razvijena zemlja bez programa obaveznog obogaćivanja hrane FA. Potrebna su dalja istraživanja o prehrambenom unosu i statusu folata u ciljnoj grupi, kao i mogućih prediktora neadekvatne suplementacije.

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Objavljeno
2020/08/24
Broj časopisa
Vol. 70 Br. Notebook 4 (2020): Arhiv za farmaciju
Rubrika
Originalni naučni rad
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