The Closing-in phenomenon: intricate aspect of constructional apraxia

  • Viktor Pavlović Institut za mentalno zdravlje, Beograd, Srbija
  • Aleksandra Parojčić Institut za mentalno zdravlje, Odeljenje za epilepsije i kliničku neurofiziologiju „Prof. dr Dragoslav Ercegovac“, Beograd, Srbija
  • Aleksandra Pavlović Fakultet za specijalnu edukaciju i rehabilitaciju, Univerzitet u Beogradu
Keywords: constructional apraxia, executive functions, dementia, attention

Abstract


The closing-in phenomenon occurs when a drawing is reproduced close to or superimposed on the original model. This phenomenon is classically understood as a type of constructional apraxia that occurs during graphomotor copying tasks or gestural imitations. Its manifestation on neuropsychological tests is taken as a neurocognitive indicator of dementia, most often as an indicator of Alzheimer's disease. Although a highly specific sign for this dementia type, current literature suggests that it is certainly not pathognomonic for Alzheimer's dementia, but occurs in a wide range of neurocognitive disorders with or without dementia. Although the Serbian academic circles are familiar with this phenomenon, thus far it hasn’t been sistematically explored. For this reason, in addition to discussing the significance of this phenomenon in clinical practice, in this paper we also summarize and critically analyze current knowledge regarding closing-in phenomenon. In this paper we discuss: (1) Historical development and conceptualization;  (2) Neuroanatomical correlates of the phenomenon; (3) Compensation hypothesis; (4) Attraction hypothesis.

References

1. De Lucia N, Grossi D, Trojano L. The genesis of closing-in in Alzheimer disease and vascular dementia: A comparative clinical and experimental study. Neuropsychology 2014; 28:312-318.

2. Ambron E, Della Sala S. A critical review of closing-in. Neuropsychology 2017; 31:105–117.

3. Ambron E, Piretti L, Lunardelli A, Coslett HB. Closing-in Behavior and Parietal Lobe Deficits: Three Single Cases Exhibiting Different Manifestations of the Same Behavior. Front. Psychol. 2018; 9:1617.

4. Pavlović DM, Pavlović AM. Neuropsihologija – od strukture do funkcije mozga. Orion Art, Beograd, 2018; 332.

5. McIntosh RD, Ambron E, Della Sala S.  Evidence for an attraction account of closing-in behaviour. Cognitive Neuropsychology 2008; 25:376–394.

6. Sagliano L, D’Olimpio F, Conson M, Cappuccio A, Grossi D, Trojano L. Inducing closing-in phenomenon in healthy young adults: The effect of dual task and stimulus complexity on drawing performance. Experimental Brain Research 2013; 225:409–418.

7. Kwon JC, Kang SJ, Lee BH, Chin J, Heilman KM, Duke L. Manual approach during hand gesture imitation. Archives of Neurology 2002; 59:1468 –1475.

8. Mayer-Gross W. Some observations on apraxia. Proceedings of the Royal Society of Medicine 1935; 28:1203–1212.

9. Gainotti G. A quantitative study of the “closing-in” symptom in normal children and in brain-damaged patients. Neuropsychologia 1972; 10:429–436.

10. Ambron E, Piretti L, Lunardelli A, Coslett HB. Closing-in Behaviorand Parietal Lobe Deficits: Three Single Cases Exhibiting Different Manifestations of the Same Behavior. Front. Psychol. 2018; 9:1617.

11. Farah MJ. Disorders of visual-spatial perception and cognition. In: Heilman KM, Valenstein E, editors. Clinical Neuropsychology. New York: Oxford University Press; 2003. p.146-60.  

12. De Lucia N, Grossi D, Maria Fasanaro A, Carpi S, Trojano L. Frontal defects contribute to the genesis of closing-in in Alzheimer’s disease patients. Journal of the International Neuropsychological Society 2013; 19:802-808.

13. Lee BH, Chin J, Kang SJ, Kim EJ, Park KC, Duke L. Mechanism of the closing-in phenomenon in a figure copying task in Alzheimer’s disease patients. Neurocase 2004; 10:393–397.

14. Chin J, Lee BH, Seo SW, Kim EJ, Suh MK, Kang SJ, Duke L. The closing-in phenomenon in Alzheimer’s disease and vascular dementia. Journal of Clinical Neurology 2005; 1:166–173.

15. Kwak YT. “Closing-in” phenomenon in Alzheimer’s disease and subcortical vascular dementia. BioMed Central Neurology 2004; 4:3.

16. Ambron E, McIntosh RD, Della Sala S. Closing-in behaviour in preschool children. Cognitive Processing 2010; 11:207–211.

17. Serra L, Fadda L, Perri R, Caltagirone C, Carlesimo G. A. The closing-in phenomenon in the drawing performance of Alzheimer’s disease patients: A compensation account. Cortex 2010; 46:1031–1036.

18. Grossi D, De Lucia N, Milan G, Trojano L. Relationships between environmental dependency and closing-in in patients with fronto-temporal dementia. Journal of the International Neuropsychological Society 2015; 21:1–7.

19. Gasparini M, Masciarelli G, Vanacore N, Ottaviani D, Salati E,Talarico G, Bruno, G. A descriptive study on constructional impairment in frontotemporal dementia and Alzheimer’s disease. European Journal of Neurology 2008; 15:589–597.

20. De Lucia N, Grossi D, Trojano L. A clinical study on closing-in in focal brain-damaged individuals. Journal of the Neurological Sciences 2016; 363:170–175.

21. Poletti M, Lucetti C, Del Dotto P, Borelli P, Baldacci F, Logi C, Bonuccelli U. The “closing-in” phenomenon in a’s disease dementia and lewy-body dementia. The Journal of Neuropsychiatry and Clinical Neurosciences 2012; 24:38–39.

22. De Lucia N, Peluso S, Roca A, Russo CV, Massarelli M, De Michele G, Di Maio L, Salvatore E, Michele G. Closing-in Phenomenon in Huntington’s Disease: A Neuropsychological Marker of Frontal/Executive Dysfunction. Archives of Clinical Neuropsychology 2019; 34:24–30.

23. Suzuki K, OtsukaY, Endo K, Ejima A, Saito H, Fujii T, Yamadori, A. Visuospatial deficits due to impaired visual attention: Investigation of two cases of slowly progressive visuospatial impairment.Cortex 2003; 39:327–341.

24. Conson M, Salzano S, Manzo V, Grossi D, Trojano L. Closing-in without severe drawing disorders: The “fatal” consequences of pathological attraction. Cortex 2009, 45:285–292.

25. Kwon SY, Lee ES, Hong YJ, Lim S, Ahn KJ,Yoon B.Yang, D. W. Anatomical correlates of the “closing-in“ phenomenon. Dementia and Neurocognitive Disorders 2015; 14:17–23.

26. Ambron E, McIntosh RD, Allaria F, Della Sala S. A large-scale retrospective study of closing-in behavior in Alzheimer’s disease. Journal of the International Neuropsychological Society 2009b; 15:787–792.

27. Ambron E, Allaria F, McIntosh RD, Della Sala S. Closing-in behaviour in fronto-temporal dementia. Journal of Neurology 2009a, 256:1004–1006.

28. Ambron E, McIntosh RD, Finotto S, Clerici F, Mariani C, Della Sala S. Closing-in behavior in mild cognitive impairment: An executive deficit. Journal of International Neuropsychological Society 2012; 18:269-76.

29. Gainotti G, Marra C, Villa G, Parlato V, Chiarotti F. Sensitivity and specificity of some neuropsychological markers of Alzheimer dementia. Alzheimer Dis Assoc Disord 1998;12:152-162.

30. Appollonio I, Leone M, Isella V, Piamarta F, Consoli T, Villa ML, Forapani E, Russo A, Nichelli P. The Frontal Assessment Battery (FAB): normative values in an Italian population sample. Neurological Sciences 2005; 26:108–116.

 

Published
2022/12/10
How to Cite
Pavlović, V., Parojčić, A., & Pavlović, A. (2022). The Closing-in phenomenon: intricate aspect of constructional apraxia. Engrami, 44(2). https://doi.org/10.5937/engrami44-37649
Section
REVIEW ARTICLES