POREMEĆAJI SPAVANJA I DEPRESIJA: POVEZANOST I MEHANIZMI INTERAKCIJE

  • Željko Z Grubač Laboratorija za neurofiziologiju, Institut za medicinsku fiziologiju “Rihard Burijan”, Medicinski fakultet, Univerzitet u Beogradu;
  • Đurđa Jovanović Institut za medicinsku i kliničku biohemiju, Medicinski fakultet, Univerzitet u Beogradu
  • Nela Puškaš Institut za histologiju i embriologiju “Aleksandar Đ Kostić, Medicinski fakultet, Univerzitet u Beogradu;
  • Dragan Hrnčić Laboratorija za neurofiziologiju, Institut za medicinsku fiziologiju “Rihard Burijan”, Medicinski fakultet, Univerzitet u Beogradu

Sažetak


Spavanje predstavlja fiziološki process, čiji efekti su presudni za održavanje organizma u homeostazi. Poremećaji spavanja su široko rasprostranjeni u svetskoj populaciji. Poremećaj u kvantitetu ili kvalitetu spavanja je usko povzan sa brojnim bolestima. Takođe, već je dokazana veza između poremećaja spavanja i depresije, ali mehanizmi njihove interakcije su, još uvek, nedovoljno razjašnjeni. Razumevanje etiologije poremećaja i mehanizama interakcije može biti od presudnog značaja za adekvatan medikamentozni tretman oba poremećaja, naročito kod pacijenata sa poremećajem spavanja koji imaju psihijatrijske i psihosomatske manifestacije. U ovom preglednom radu biće sabrana najnovija saznanja o povezanosti izmađu poremećaja spavanja i depresije uključujući i potencijalne mehanizme njihove interakcije.

ključne reči: spavanje, depresija, poremećaj spavanja, BDNF

 

Biografije autora

Željko Z Grubač, Laboratorija za neurofiziologiju, Institut za medicinsku fiziologiju “Rihard Burijan”, Medicinski fakultet, Univerzitet u Beogradu;
Student doktorskih akademskih studija
Đurđa Jovanović, Institut za medicinsku i kliničku biohemiju, Medicinski fakultet, Univerzitet u Beogradu
Student doktorskih akademskih studija; Saradnik u nastavi na katedri za medicinsku biohemiju
Nela Puškaš, Institut za histologiju i embriologiju “Aleksandar Đ Kostić, Medicinski fakultet, Univerzitet u Beogradu;
Profesor za užu naučnu oblast histologija sa embriologijom
Dragan Hrnčić, Laboratorija za neurofiziologiju, Institut za medicinsku fiziologiju “Rihard Burijan”, Medicinski fakultet, Univerzitet u Beogradu
Docent za užu naučnu oblast medicinska fiziologija

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2018/10/27
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