SAVREMENA RADIOTERAPIJA RABDOMIOSARKOMA DECE

Marija Popović-Vuković; Borko Nidžović; Marina Nikitović

doi:10.5937/mp71-24163

Marija Popović-Vuković Institut za onkologiju i radiologiju Srbije
Borko Nidžović Institut za onkologiju i radiologiju Srbije
Marina Nikitović Institut za onkologiju i radiologiju Srbije Medicinski fakultet, Univerzitet u Beogradu

DOI: https://doi.org/10.5937/mp71-24163

Sažetak

Rabdomiosarkom je najčešći sarkom mekih tkiva kod dece i čini polovinu svih sarkoma mekih tkiva. Tumor nastaje iz primitivnih mezenhimalnih ćelija koje se diferenciraju u pravcu poprečno-prugaste muskulature i najčešće je lokalizovan u regiji glave i vrata, na genitourinarnom traktu i ekstremitetima.

Terapija je multimodalna i uključuje primenu hirurgije, radioterapije i hemioterapije. Primena kombinovane terapije dovela je do značajnog poboljšanja u rezultatima lečenja. Obzirom na dugogodišnje preživljavanje, veliki značaj pridaje se očekivanim terapijskim komplikacijama. Lečenje rabdomiosarkoma dečijeg uzrasta zahteva delikatan balans između potrebe da se intenzivira terapija za određenu grupu pacijenata i želje da se redukuje potencijalno toksična terapija i rizik od sekundarnih maligniteta kod dece sa dobrom prognozom.Radioterapija ima veoma značajnu ulogu u lokalnoj kontroli bolesti i sprovodi kod skoro svih pacijenata. Obzirom da se primenjuje na organima i tkivima koji se nalaze u fazi rasta i razvoja radioterapija kod dece ima svoje specifičnosti i predstavlja veći izazov u odnosu na lečenje odraslih pacijenata.

Primenom savremenih tehnika radioterapije postiže se odlična lokalna kontrola bolesti uz bolju poštedu okolnih zdravih tkiva i organa što redukuje toksičnost radioterapije i dovodi do očuvanja kvaliteta života lečene dece.

Biografije autora

Marija Popović-Vuković, Institut za onkologiju i radiologiju Srbije

Dnevna bolnica za radioterapiju-odsek za pedijatrijsku radioterapiju, specijalista radijacioni onkolog

Borko Nidžović, Institut za onkologiju i radiologiju Srbije

Dnevna bolnica radioterapije, Odsek za planiranje transkutane radioterapije, medicinski fizičar

Marina Nikitović, Institut za onkologiju i radiologiju Srbije Medicinski fakultet, Univerzitet u Beogradu

pomoćnik direktora za obrazovnu i naučnoistraživačku delatnost

profesor onkologije i radiologije

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