Karakteristike COVID-19 u primarnoj zdravstvenoj zaštiti u Beogradu (Srbija) i uticaj sociodemografskih karakteristika ispitanika na vakcinaciju

  • Marina Fisekovic Kremic Dom zdravlja Novi Beograd
Ključne reči: Covid-19, kliničke karakteristike, CRP, vakcinacija

Sažetak


Uvod. Pandemija korona virusa је počela 2019. godine
od kada je zaražen veliki broj ljudi širom sveta. Simptomi
infekcije su široko definisani, ali još uvek nedostaje pregled
laboratorijskih abnormalnosti pronađenih kod pacijenata sa
infekcijom.
Cilj studije je bio opis kliničkih i laboratorijskih karakteristika
pacijenata obolelih od COVID-19 infekcije u
Beogradu (Srbija) i uticaj socio-demografskih karakteristika
ispitanika na vakcinaciju.
Metod. Istraživanje je sprovedeno kao studija preseka
u periodu od oktobra do novembra 2021. godine. U studiju
su uključeni pacijenti koji su u ovom periodu posetili Kovid
ambulantu doma zdravlja i kod kojih je potvrđena infekcija
virusom Sars-CoV-2. Podaci su prikupljeni pregledom zdravstvenog
kartona pacijenata, retrospektivno. Podaci su analizirani
deskriptivnom statistikom i Pirsonovim χ2 testom, i
analizirani su SPSS 20.
Rezultati. U istraživanju je učestvovalo 207 Sars-
CoV-2 pozitivnih pacijenata, od kojih je bilo 56% osoba ženskog
pola, a najveći broj ispitanika bio je u starosnoj grupi
51–60 godina (22,7%). Vakcinisano je 42% ispitanika. Najčešći
simptomi koje su ispitanici prijavljivali bili su: povišena
telesna temperatura (82,1%), kašalj (49,8%), malaksalost
(32,9%), zapušen nos (29,5%), bol u grlu (17,9%), glavobolja
(12,1%), bol u telu (11,1%), gubitak ukusa i mirisa (8,2%),
dijareja (2,4%). Pneumoniju je imalo 17,4% ispitanika, povišene
vrednosti CRP 29%.
Zaključak. Najčešće kliničke karakteristike obolelih
od COVID-19 u Beogradu (Srbija) bile su povišena telesna
temperatura, kašalj, malaksalost. Pneumoniju je imalo 17,4%
pacijenata. Najveći broj pacijenata je imao normalan laboratorijski
nalaz krvne slike, ali povišene vrednosti CRP (29%).
Vakcinisanih nekom od trenutno dostupnih vakcina bilo je
42%, od kojih je bez komorbiditeta bilo 52,9%.

Reference

Normal

0

false

false

false

EN-US

X-NONE

X-NONE

DefSemiHidden="false" DefQFormat="false" DefPriority="99"

LatentStyleCount="371">

UnhideWhenUsed="true" QFormat="true" Name="heading 2"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 3"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 4"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 5"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 6"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 7"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 8"/>

UnhideWhenUsed="true" QFormat="true" Name="heading 9"/>

Name="index 1"/>

Name="index 2"/>

Name="index 3"/>

Name="index 4"/>

Name="index 5"/>

Name="index 6"/>

Name="index 7"/>

Name="index 8"/>

Name="index 9"/>

UnhideWhenUsed="true" Name="toc 1"/>

UnhideWhenUsed="true" Name="toc 2"/>

UnhideWhenUsed="true" Name="toc 3"/>

UnhideWhenUsed="true" Name="toc 4"/>

UnhideWhenUsed="true" Name="toc 5"/>

UnhideWhenUsed="true" Name="toc 6"/>

UnhideWhenUsed="true" Name="toc 7"/>

UnhideWhenUsed="true" Name="toc 8"/>

UnhideWhenUsed="true" Name="toc 9"/>

Name="Normal Indent"/>

Name="footnote text"/>

Name="annotation text"/>

Name="header"/>

Name="footer"/>

Name="index heading"/>

UnhideWhenUsed="true" QFormat="true" Name="caption"/>

Name="table of figures"/>

Name="envelope address"/>

Name="envelope return"/>

Name="footnote reference"/>

Name="annotation reference"/>

Name="line number"/>

Name="page number"/>

Name="endnote reference"/>

Name="endnote text"/>

Name="table of authorities"/>

Name="macro"/>

Name="toa heading"/>

Name="List"/>

Name="List Bullet"/>

Name="List Number"/>

Name="List 2"/>

Name="List 3"/>

Name="List 4"/>

Name="List 5"/>

Name="List Bullet 2"/>

Name="List Bullet 3"/>

Name="List Bullet 4"/>

Name="List Bullet 5"/>

Name="List Number 2"/>

Name="List Number 3"/>

Name="List Number 4"/>

Name="List Number 5"/>

Name="Closing"/>

Name="Signature"/>

UnhideWhenUsed="true" Name="Default Paragraph Font"/>

Name="Body Text"/>

Name="Body Text Indent"/>

Name="List Continue"/>

Name="List Continue 2"/>

Name="List Continue 3"/>

Name="List Continue 4"/>

Name="List Continue 5"/>

Name="Message Header"/>

Name="Salutation"/>

Name="Date"/>

Name="Body Text First Indent"/>

Name="Body Text First Indent 2"/>

Name="Note Heading"/>

Name="Body Text 2"/>

Name="Body Text 3"/>

Name="Body Text Indent 2"/>

Name="Body Text Indent 3"/>

Name="Block Text"/>

Name="Hyperlink"/>

Name="FollowedHyperlink"/>

Name="Document Map"/>

Name="Plain Text"/>

Name="E-mail Signature"/>

Name="HTML Top of Form"/>

Name="HTML Bottom of Form"/>

Name="Normal (Web)"/>

Name="HTML Acronym"/>

Name="HTML Address"/>

Name="HTML Cite"/>

Name="HTML Code"/>

Name="HTML Definition"/>

Name="HTML Keyboard"/>

Name="HTML Preformatted"/>

Name="HTML Sample"/>

Name="HTML Typewriter"/>

Name="HTML Variable"/>

Name="Normal Table"/>

Name="annotation subject"/>

Name="No List"/>

Name="Outline List 1"/>

Name="Outline List 2"/>

Name="Outline List 3"/>

Name="Table Simple 1"/>

Name="Table Simple 2"/>

Name="Table Simple 3"/>

Name="Table Classic 1"/>

Name="Table Classic 2"/>

Name="Table Classic 3"/>

Name="Table Classic 4"/>

Name="Table Colorful 1"/>

Name="Table Colorful 2"/>

Name="Table Colorful 3"/>

Name="Table Columns 1"/>

Name="Table Columns 2"/>

Name="Table Columns 3"/>

Name="Table Columns 4"/>

Name="Table Columns 5"/>

Name="Table Grid 1"/>

Name="Table Grid 2"/>

Name="Table Grid 3"/>

Name="Table Grid 4"/>

Name="Table Grid 5"/>

Name="Table Grid 6"/>

Name="Table Grid 7"/>

Name="Table Grid 8"/>

Name="Table List 1"/>

Name="Table List 2"/>

Name="Table List 3"/>

Name="Table List 4"/>

Name="Table List 5"/>

Name="Table List 6"/>

Name="Table List 7"/>

Name="Table List 8"/>

Name="Table 3D effects 1"/>

Name="Table 3D effects 2"/>

Name="Table 3D effects 3"/>

Name="Table Contemporary"/>

Name="Table Elegant"/>

Name="Table Professional"/>

Name="Table Subtle 1"/>

Name="Table Subtle 2"/>

Name="Table Web 1"/>

Name="Table Web 2"/>

Name="Table Web 3"/>

Name="Balloon Text"/>

Name="Table Theme"/>

Name="List Paragraph"/>

Name="Intense Quote"/>

Name="Subtle Emphasis"/>

Name="Intense Emphasis"/>

Name="Subtle Reference"/>

Name="Intense Reference"/>

UnhideWhenUsed="true" Name="Bibliography"/>

UnhideWhenUsed="true" QFormat="true" Name="TOC Heading"/>

Name="Grid Table 1 Light Accent 1"/>

Name="Grid Table 6 Colorful Accent 1"/>

Name="Grid Table 7 Colorful Accent 1"/>

Name="Grid Table 1 Light Accent 2"/>

Name="Grid Table 6 Colorful Accent 2"/>

Name="Grid Table 7 Colorful Accent 2"/>

Name="Grid Table 1 Light Accent 3"/>

Name="Grid Table 6 Colorful Accent 3"/>

Name="Grid Table 7 Colorful Accent 3"/>

Name="Grid Table 1 Light Accent 4"/>

Name="Grid Table 6 Colorful Accent 4"/>

Name="Grid Table 7 Colorful Accent 4"/>

Name="Grid Table 1 Light Accent 5"/>

Name="Grid Table 6 Colorful Accent 5"/>

Name="Grid Table 7 Colorful Accent 5"/>

Name="Grid Table 1 Light Accent 6"/>

Name="Grid Table 6 Colorful Accent 6"/>

Name="Grid Table 7 Colorful Accent 6"/>

Name="List Table 1 Light Accent 1"/>

Name="List Table 6 Colorful Accent 1"/>

Name="List Table 7 Colorful Accent 1"/>

Name="List Table 1 Light Accent 2"/>

Name="List Table 6 Colorful Accent 2"/>

Name="List Table 7 Colorful Accent 2"/>

Name="List Table 1 Light Accent 3"/>

Name="List Table 6 Colorful Accent 3"/>

Name="List Table 7 Colorful Accent 3"/>

Name="List Table 1 Light Accent 4"/>

Name="List Table 6 Colorful Accent 4"/>

Name="List Table 7 Colorful Accent 4"/>

Name="List Table 1 Light Accent 5"/>

Name="List Table 6 Colorful Accent 5"/>

Name="List Table 7 Colorful Accent 5"/>

Name="List Table 1 Light Accent 6"/>

Name="List Table 6 Colorful Accent 6"/>

Name="List Table 7 Colorful Accent 6"/>

/* Style Definitions */

table.MsoNormalTable

{mso-style-name:"Table Normal";

mso-tstyle-rowband-size:0;

mso-tstyle-colband-size:0;

mso-style-noshow:yes;

mso-style-priority:99;

mso-style-parent:"";

mso-padding-alt:0cm 5.4pt 0cm 5.4pt;

mso-para-margin-top:0cm;

mso-para-margin-right:0cm;

mso-para-margin-bottom:8.0pt;

mso-para-margin-left:0cm;

line-height:107%;

mso-pagination:widow-orphan;

font-size:11.0pt;

font-family:"Calibri",sans-serif;

mso-ascii-font-family:Calibri;

mso-ascii-theme-font:minor-latin;

mso-hansi-font-family:Calibri;

mso-hansi-theme-font:minor-latin;

mso-bidi-font-family:"Times New Roman";

mso-bidi-theme-font:minor-bidi;}

1. Huang C, Wang Y, Li X, Ren L,
Zhao J, Hu Y, et al. Clinical features
of patients infected with 2019 novel
coronavirus in Wuhan, China. Lancet
2020;395(10223):497–506. doi: 10.1016/
S0140-6736(20)30183-5.
2. Wang D, Hu B, Hu C, Zhu F, Liu X,
Zhang J, et al. Clinical Characteristics
of 138 Hospitalized Patients With
2019 Novel Coronavirus-Infected
Pneumonia in Wuhan, China. JAMA
2020;323(11):1061–9. doi: 10.1001/
jama.2020.1585.
3. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou
CQ, He JX, et al. Clinical characteristics
of coronavirus disease in China. N Engl J
Med 2020;382(18):1708–20. doi: 10.1056/
NEJMoa2002032.
4. Ali HN, Ali KM, Rostam HM, Ali AM,
Tawfeeq HM, Fatah MH, et al. Clinical
laboratory parameters and comorbidities
associated with severity of coronavirus
disease 2019 (COVID-19) in
Kurdistan Region of Iraq. Pract Lab
Med 2022;31:e00294. doi: 10.1016/j.
plabm.2022.e00294.
5. Fei F, Smith JA, Cao L. Clinical
laboratory characteristics in patients
with suspected COVID‐19: One singleinstitution
experience. J Med Virol 2021;
93(3):1665–71. doi: 10.1002/jmv.26527.
6. Fan BE. Hematologic parameters in
patients with COVID-19 infection: a reply.
Am J Hematol 2020;95(8):E215. doi:
10.1002/ajh.25847.
7. Zhou F, Yu T, Du R, Fan G, Liu Y,
Liu Z, et al. Clinical course and risk
factors for mortality of adult inpatients
with COVID‐19 in Wuhan, China:
a retrospective cohort study. Lancet
2020;395(10229):1054–62. doi: 10.1016/
S0140-6736(20)30566-3.
8. Ghayda RA, Lee J, Lee JY, Kim DK,
Lee KH, Hong SH, et al. Correlations
of clinical and laboratory characteristics
of COVID‐19: a systematic review and
meta‐analysis. Int J Environ Res Public
Health 2020;17(14):5026. doi: 10.3390/
ijerph17145026.
9. Kremic MF, Ristic SS. SaRS-CoV-2:
Epidemiološke karakteristike, klinička
slika, dijagnostika i prevencija - pregled
dosadašnjih saznanja. Srpski medicinski
časopis Lekarske komore 2021;2(2):16–
22. doi: 10.5937/smclk2-30845
10. Leung GM, Lam TH, Ho LM, Ho
SY, Chan BHY, Wong IOL, et al. The
impact of community psychological
responses on outbreak control for severe
acute respiratory syndrome in Hong
Kong. J Epidemiol Community Health
2003;57(11):857–63. doi: 10.1136/
jech.57.11.857.

11. Petrov-Kiurski MĐ, Živanović SR.
Kliničke karakteristike i dijagnostika
COVID-19 kod pacijenata u COVIDambulantama
u opštoj medicini. Opšta
medicina 2022;28(1-2):14–26. doi:
10.5937/opmed28-35902.
12. Wang J, Jing R, Lai X, Zhang H, Lyu Y,
Knoll MD, et al. Acceptance of COVID-19
Vaccination during the COVID-19
Pandemic in China. Vaccines
(Basel) 2020;8(3):482. doi: 10.3390/
vaccines8030482.
13. Nguyen T, Henningsen KH, Brehaut
JC, Hoe E, Wilson K. Acceptance of a
pandemic influenza vaccine: A systematic
review of surveys of the general public.
Infect Drug Resist 2011;4:197–207.
14. Determann D, Korfage IJ, Lambooij
MS, Bliemer M, Richardus JH,
Steyerberg EW, et al. Acceptance of
Vaccinations in Pandemic Outbreaks: A
Discrete Choice Experiment. PLoS One
2014;9(7):e102505. doi: 10.1371/journal.
pone.0102505.
15. Alimohamadi Y, Sepandi M, Taghdir
M, Hosamirudsari H. Determine the
most common clinical symptoms in
COVID-19 patients: a systematic
review and meta-analysis. J Prev Med
Hyg 2020;61(3):E304–E312. doi:
10.15167/2421-4248/jpmh2020.61.3.1530.
16. Huang C, Wang Y, Li X, Ren L,
Zhao J, Hu Y, et al. Clinical features
of patients infected with 2019 novel
coronavirus in Wuhan, China. Lancet
2020;395(10223):497–506. doi: 10.1016/
S0140-6736(20)30183-5.
17. Yu N, Li W, Kang Q, Xiong Z, Wang S,
Lin X, et al. Clinical features and obstetric
and neonatal outcomes of pregnant
patients with COVID-19 in Wuhan, China:
a retrospective, single-centre, descriptive
study. Lancet Infect Dis 2020;20(5):559–
64. doi: 10.1016/S1473-3099(20)30176-6.
18. Kumar A, Arora A, Sharma P, Anikhindi
SA, Bansal N, Singla V, et al. Clinical
features of COVID-19 and factors
associated with severe clinical course:
a systematic review and meta-analysis.
Available at SSRN: https://dx.doi.
/>org/10.2139/ssrn.3566166.
19. Chen W, Zheng KI, Liu S, Yan Z, Xu C,
Qiao Z. Plasma CRP level is positively
associated with the severity of COVID-19.
Ann Clin Microbiol Antimicrob
2020;19(1):18. doi: 10.1186/s12941-020-
00362-2.
20. Goyal D, Inada-Kim M, Mansab F, Iqbal A,
McKinstry B, Naasan AP, et al. Improving
the early identification of COVID-19
pneumonia: a narrative review. BMJ
Open Respir Res 2021; 8(1):e000911. doi:
10.1136/bmjresp-2021-000911.

21. Shi F, Wu T, Zhu X, Ge Y, Zeng X, Chi
Y, et al. Association of viral load with
serum biomakers among COVID-19 cases.
Virology 2020;546:122–6. doi: 10.1016/j.
virol.2020.04.011.
22. Jalil AT, Shanshool MT, Dilfy SH, Saleh
MM, Suleiman AA. Hematological and
serological parameters for detection of
COVID-19. J Microbiol Biotech Food
Sci 2022;11(4):e4229. doi: https://doi.
/>org/10.55251/jmbfs.4229.
23. Du RH, Liang LR, Yang CQ, Wang
W, Cao TZ, Li M, et al. Predictors of
mortality for patients with COVID-19
pneumonia caused by SARS-CoV-2:
a prospective cohort study. Eur
Respir J 2020;55(5):2000524. doi:
10.1183/13993003.00524-2020.
24. Chen N, Zhou M, Dong X, Qu J, Gong
F, Han Y, et al. Epidemiological and
clinical characteristics of 99 cases of
2019 novel coronaviruspneumonia in
Wuhan, China: a descriptive study. Lancet
2020;395(10223):507–13. doi: 10.1016/
S0140-6736(20)30211-7.
25. Wang L. C-reactive protein levels in
the early stage of COVID-19. Med Mal
Infect 2020;50(4):332–4. doi: 10.1016/j.
medmal.2020.03.007.
26. Hwang J, Ryu HS, Kim HA, Hyun
M, Lee JY, Yi HA. Prognostic factors
of COVID-19 infection in elderly
patients: a multicenter study. J Clin
Med 2020;9(12):3932. doi: 10.3390/
jcm9123932.
27. Choi Y, Kim JS, Kim JE, Choi H, Lee
CH. Vaccination prioritization strategies
for COVID-19 in Korea: a mathematical
modeling approach. Int J Environ Res
Public Health 2021;18(8):4240. doi:
10.3390/ijerph18084240.
28. Razai MS, Chaudhry UAR, Doerholt K,
Bauld L, Majeed A. Covid-19 vaccination
hesitancy. BMJ 2021;373:n1138. doi:
10.1136/bmj.n1138.

Objavljeno
2023/10/04
Kako citirati
Fisekovic Kremic, M. (2023). Karakteristike COVID-19 u primarnoj zdravstvenoj zaštiti u Beogradu (Srbija) i uticaj sociodemografskih karakteristika ispitanika na vakcinaciju. Opšta Medicina, 29(3-4), 33-40. https://doi.org/10.5937/opmed29-41126
Rubrika
originalni rad