ZNAČAJ BRZE DIJAGNOSTIKE SARS-CoV-2, DOBRE ZDRAVSTVENE ORGANIZACIJE I RAZUMNOG KORIŠĆENJA ZNANJA I RESURSA TOKOM BORBE PROTIV KOVID-19

  • Valentina Arsić Arsenijević Institut za mikrobiologiju i imunologiju, Medicinski fakultet Univerziteta u Beogradu, Beograd, Srbija
  • Miha Skvarc Opšta bolnica Jesenice, Jesenice, Slovenija
Ključne reči: Kovid-19, SARS-CoV-2, mikrobiološka dijagnostika, zdravstveni radnici, znanje, resursi

Sažetak


U decembru 2019. godine pojavila se nova bolest, upala pluća nepoznatog uzroka, povezana sa
pijacom morskih plodova u mestu Vuhan (Kina). Na humanim epitelnim ćelijama respiratornog trakta
je izolovan jedan nov koronavirus, nazvan prema kliničkoj slici „teški akutni respiratorni sindrom
korona virus 2” (SARS-CoV-2), dok je bolest nazvana koronavirusna bolest 2019 (Kovid-19). Pokazalo
se da je ova pandemija veliki izazov, kako za stručnjake koji se bave mikorbiološkom dijagnostikom,
tako i za sve zdravstvene radnike. Cilj ovog rada je da prikaže značaj brze dijagnostike SARS-CoV-2,
značaj zaštite zdravlja zdravstvenih radnika i razumnog korišćenja znanja i resursa tokom borbe
protiv Kovid-19. Dosadašnja istraživanja potvrđuju da su u borbi protiv SARS-CoV-2 infekcije od
posebnog značaja brza dijagnostika SARS-CoV-2, zaštita zdravlja zdravstvenih radnika i razumno
korišćenje znanja i resursa tokom pandemije. Poseban akcenat se stavlja na sprovođenje vakcinisanja
protiv sezonskog gripa, kao i protiv invazivne pneumokokne bolesti, jer primenom ovih vakcina
možemo olakšati postavljanje dijagnoze Kovid-19 u budućem period u kome se sa velikim nadama
očekuje efikasna antivirusna terapija za SARS-CoV-2 i vakcina za Kovid-19.

Reference

European Centre for Disease Prevention and Control.

An agency of the European Union. Diagnostic testing

and screening for SARS-CoV-2. [Internet] Available

at: https://www.ecdc.europa.eu/en/covid-19/latestevidence/

diagnostic-testing [Accessed 3rd Apr 2020]

Coronaviridae Study Group of the International

Committee on Taxonomy of Viruses. The species

Severe acute respiratory syndrome-related

coronavirus: classifying 2019-nCoV and naming it

SARS-CoV-2. Nat Microbiol 2020; 5(4):536-544.

Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A

novel coronavirus from patients with pneumonia in

China, 2019. N Engl J Med 2020; 382(8):727-33.

WHO. Coronavirus disease 2019 (COVID-19) situation

reports. [Internet] Available at: https://www.who.

int/emergencies/diseases/novel-coronavirus-2019/

situation-reports[Accessed 3rd Apr 2020)

Dong E, Du H, Gardner L. An interactive web-based

dashboard to track COVID-19 in real time. Lancet

Infect Dis 2020; 20(5):P533-534.

Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course

and risk factors for mortality of adult inpatients with

COVID-19 in Wuhan, China: a retrospective cohort

study. Lancet 2020; pii: S0140-6736(20)30566-3.

Remuzzi A, Remuzzi G. COVID-19 and Italy: what

next? Lancet 2020; 395(10231):P1225-28.

Guan W, Liang W, Zhao Y, Liang, Chen Z, Li Y, et al.

Comorbidity and its impact on 1590 patients with

Covid-19 in China: A Nationwide Analysis. Eur Respir

J 2020; 55(5):2000547.

Yu J, Ouyang W, Chua M, Xie C. SARS-CoV-2

Transmission in Patients With Cancer at a Tertiary

Care Hospital in Wuhan, China. JAMA Oncol 2020;

(7):1108-10.

Liang W, Guan W, Chen R, Wang W, Li J, Xu K, et al.

Cancer patients in SARS-CoV-2 infection: a nationwide

analysis in China. Lancet Oncol 2020; 21(3):335-337.

Nalla AK, Casto AM, Huang MW, Perchetti GA, Sampoleo

R, Shrestha L, et al. Comparative Performance of

SARS-CoV-2 Detection Assays using Seven Different

Primer/Probe Sets and One Assay Kit. J Clin Microbiol

; 58(6):e00557-20.

Khan S, Siddique R, Shereen MA, Ali A, Liu J, Bai Q,

et al. The emergence of a novel coronavirus (SARSCoV-

, their biology and therapeutic options. J Clin

Microbiol 2020; 58(5):e00187-20.

Alhazzani W, Møller MH, Arabi YM, Loeb M, Ng Gong

M, Fan E, et al. Surviving Sepsis Campaign: guidelines

on the management of critically ill adults with

Coronavirus Disease 2019 (COVID-19) Intensive Care

Med 2020; 46: 854-87.

ECDC. Novel coronavirus (SARS-CoV-2) - Discharge

criteria for confirmed COVID-19 cases. [Internet]

Available at: https://www.ecdc.europa.eu/sites/

default/files/documents/COVID-19-Dischargecriteria.

pdf [Accessed 3rd Apr 2020].

Wölfel R, Corman VM, Guggemos W, Seilmaier M,

Zange S, Müller MA, et al. Virological assessment of

hospitalized patients with COVID-2019. Nature. 2020;

:465-69. doi: 10.1038/s41586-020-2196-x.

Nickel CH, Bingisser R. Mimics and chameleons of

COVID-19. Swiss Med Wkly. 2020; 150:w20231.

Michael J. Loeffelholz, Yi-Wei Tang. Laboratory

diagnosis of emerging human coronavirus infections

– the state of the art. Emerging Microbes & Infections

; 1:747-56.

Moriyama M, Hugentobler WJ, Iwasaki A. Seasonality

of Respiratory Viral Infections. Annu Rev Virol 2020;

:386-390.

FDA. Emergency Use Authorization. In Vitro

Diagnostics EUAs. [Internet] Available at: https://

www.fda.gov/medical-devices/emergencysituations-

medical-devices/emergency-useauthorizations#

covid19ivd [Accessed 3rd Apr 2020]

NHS England. Clinical guide for the management of

noncoronavirus patients requiring acute treatment:

Cancer. 23 March 2020 Version 2. Available at:

https://www.england.nhs.uk/coronavirus/wpcontent/

uploads/sites/52/2020/03/specialtyguide-

acute-treatment-cancer-23-march-2020.pdf

[Accessed 3rd Apr 2020]

van Doremalen N, Bushmaker T, Morris DH, Holbrook

MG, Gamble A, Williamson BN, et al. Aerosol and

Surface Stability of SARS-CoV-2 as Compared with

SARS-CoV-1. N Engl J Med 2020; 382:1564-67.

Haveri A, Smura T, Kuivanen S, Österlund P, Hepojoki

J, Ikonen N, et al. Serological and molecular findings

during SARS-CoV-2 infection: the first case study in

Finland, January to February 2020. Euro Surveill

; 25(11): pii=2000266.

Emanuel EJ, Persad G, Upshur R, Thome B, Parker M,

Glickman A, et al. Fair Allocation of Scarce Medical

Resources in the Time of Covid-19. N Engl J Med.

; 382:2049-55.

Krause PJ, Gross PA, Barrett TL, Dellinger EP, Martone

WJ, McGowan JE Jr, et al. Quality standard for

assurance of measles immunity among health care

workers. The Infectious Diseases Society of America.

Infect Control Hosp Epidemiol 1994; 15(3):193-9.

Koo JR, Cook AR, Park M, Sun Y, Sun H, Lim JT, et al.

Interventions to mitigate early spread of SARS-CoV-2

in Singapore: a modelling study. Lancet Infect Dis

; 20(6):P678-688.

Hall LH, Johnson J, Watt I, Tsipa A, O'Connor DB.

Healthcare Staff Wellbeing, Burnout, and Patient

Safety: A Systematic Review. PLoS One 2016;

(7):e0159015.

Burton A, Burgess C, Dean S, Koutsopoulou GZ,

Hugh-Jones S. How Effective are Mindfulness-Based

Interventions for Reducing Stress Among Healthcare

Professionals? A Systematic Review and Meta-

Analysis. Stress Health 2017; 33(1):3-13.

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2020/10/20
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