Incidence and types of vascuar accesses in patients on chronic hemodialysis

  • Nikola B Marić University of Belgrade, Faculty of Medicine
  • Voin Lj Brković Clinic of nephrology, Clinical center of Serbia

Abstract


Introduction: End-stage renal disease is the last stage of chronic renal disease and it is treated with renal replacement therapy. Hemodialysis (HD) represents a type of renal replacement therapy, which requires a vascular access. Types of vascular accesses are: arteriovenous fistula (AVF), arteriovenous graft (AVG) and Hickman line. If there is no vascular access, central venous catheter (CVC) can also be used.

Aim: To present the incidence and types of vascular accesses for hemodialysis in patients with ESRD, as well as analyse different types of vascular accesses and their complications in regard with the clinical and demographic characteristics of the participants.

Materials and methods: Study included 153 participants treated at Clinic of nephrology, Clinical Center of Serbia, during 2014 and 2015. Participants were admissioned to create vascular access prior to hemodialysis, to immediatly start hemodialysis due to uremic syndrome, and patients whose vascular access was malfunctioning. Clinical and demographic data was collected from medical records.

Results: The most often created vascular access was primary AVF (68,7%), REDO AVF was created to 11,1% while Hickman line was implanted to 15%, and AVG to 3,9% patients (p<0,001). Patients with Hickman line were significantly older (72 vs. 63, p=0,013) and had a higher mortality rate (17,4% vs. 3,1%, p=0,004) compared to patients with AVF and AVG. Vascular access thrombosis was the most common complication (80% vs. 20%, p<0,001). Central venous catheter for HD was placed in 19,6% cases, due to nonexistent vascular access, and in 23,5% CVC was used until the maturation of vascular access. Mortality rate was significantly lower in patients with prior created vascular access, than in those who had to be put on emergency dialysis via CVC (3,3% vs. 13,3%, p=0,026).

Conclusion: AVF is the most common vascular access for HD. Most dominant complication of vascular access is its thrombosis. Elective creation of vascular access for HD significantly affects mortality rate.

Keywords:  end-stage renal  disease, hemodialysis, vascular access

References

Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Inter Suppl. 2013; 3: 1-150

Smart NA, Titus TT. Outcomes of early versus late nephrology referral in chronic kidney disease: a systematic review. Am J Med 2011; 124(11): 1073-80.e2.

Simić Ogrizović S. Godišnji izveštaji o lečenju dijalizama i transplantacijom bubrega u Srbiji, 2014. godine. Udruženje nefrologa Srbije. 2014.

ERA-EDTA Registry: ERA-EDTA Registry Annual Report 2014. Academic Medical Center, Department of Medical Informatics, Amsterdam, the Netherlands, 2016

Pisoni RL, Zepel L, Pork FK et al. Trends in US Vascular Access Use, Patient Preferences, and Related Practices: An Update From US DOPPS Practice Monitor With International Comparisons. Am J Kidney Dis 2015; 65(6): 905-15.

Vascular Access 2006 Work Group. Clinical practice guidelines for vascular access. Am J Kidney Dis 2006; 48: S176–S247.

Al-Jaishi AA, Liu AR, Lok CE et al. Complications of the Arteriovenosus Fistula: A Systematic Review. J Am Soc Nephrol 2016; pii: ASN.2016040412.

Elseviers MM, Van Waeleghem JP; European Dialysis and Transplant Nurses Association/European Renal Care Association. Identifying vascular access complications among ESRD patients in Europe. A prospective, multicenter study. Nephrol News Issues 2003; 17(8): 61-4

Fokou M, Teyang A, Ashuntantang G et al. Complications of arteriovenous fistula for hemodialysis: an 8-year study. Ann Vasc Surg 2012; 26(5): 680-4.

Bick RL, Baker WF. Antiphospholipid syndrome and thrombosis. Semin Thromb Hemost 1999; 25(3): 333-50.

Mitrović D, Popović M, Stefanović D et al. Antiphospholipid syndrome in systemic connective tissue diseases. Vojnosanit Pregl 1998; 55(2 Suppl): 29-33.

Schwab S, Besarab A, Beathard G et al. NKF-KDOQI clinical practice guidelines for hemodialysis vascular access. Am J Kidney Dis 1997; 30(Suppl 3): S137–S181

Rivara MB, Soohoo M, Streja E et. al. Association of Vascular Access Type with Mortality, Hospitalization, and Transfer to In-Center Hemodialysis in Patients Undergoing Home Hemodialysis. Cllin Am Soc Nephrol 2016; 11(2): 298-307

Lorenzo V, Martin M, Rufino M et al. Predialysis nephrologic care and a functioning arteriovenous fistula at entry are associated with better survival in incident hemodialysis patients: an observational cohort study. Am J Kidney Dis 2004; 43(6): 999-1007

Published
2018/04/24
Section
Original Scientific Paper