SURGICAL TREATMENT OF FOOT DROP AFTER PERONEAL NERVE INJURY
Abstract
Foot drop is a common clinical condition presented as an inability to lift the forefoot, characterized by the loss of ankle dorsiflexion from the tibialis anterior and loss of foot eversion from the peroneus longus and brevis muscles, followed by sensory loss or numbness of the foot dorsum. Causes of a foot drop can happen at any level of the nerve path. By their nature, lesions can be divided into compressive disorders, traumatic injuries, and neurologic disorders. Peroneal palsy, due to compression, is the most common peripheral cause. Treatment and diagnosis of foot drop still need to be better standardized, given that foot drop is still considered a clinical sign in other conditions. Regarding the multidisciplinary nature of foot drop, it can be challenging to determine the cause. Surgical and conservative treatments have their own respective places. Conservative procedures used for foot drop treatment include physical therapy, functional electrical stimulation, orthosis and braces, assistive devices, and gait training. Depending on a different etiological factor that causes foot drop, a few different surgical techniques are available for successful surgical treatment. Peroneal nerve release is considered a low-risk procedure with excellent results, such as pain relief and return of function. If the nerve continuity is not preserved nerve repair with epineural stitches under magnification is performed. Another surgical approach proven successful in literature is nerve transfer. Sural nerve is usually donor graft. For tendon transfer tibialis posterior muscle is usually chosen. As it is inserted at the dorsum of the foot, it helps with dorsiflexion. After all surgical procedures, it is advised for patients to start with early mobilization and postoperative physical therapy. Better treatment standardization of foot drop is still needed. However, surgical procedures show high success rates, better results, and faster recovery if performed within the first months of injury.
References
References
1. Aprile I, Caliandro P, La Torre G, Tonali P, Foschini M, Mondelli M, et al. Multicenter study of peroneal mononeuropathy: clinical, neurophysiologic, and quality of life assessment. J Peripher Nerv Syst. 2005;10(3):259-68.
2. Poage C, Roth C, Scott B. Peroneal Nerve Palsy: Evaluation and Management. J Am Acad Orthop Surg. 2016;24(1):1-10.
3. Nori SL. Stretanski MF. Foot Drop. In: StatPearls (Internet).Treasure Island (FL): StatPearls Publishing; 2023.
4. Carolus AE, Becker M, Cuny J, Smektala R, Schmeider K, Brenke C. The Interdisciplinary Management of Foot Drop. Dtsch Arztebl Int. 2019;116(20):347-54.
5. Baysefer A, Erdogan E, Sali A, Sirin S, Seber N. Foot drop following brain tumors: case reports. Minim Invasive Neurosurg. 1998;41(2):97–8.
6. Westhout FD, Paré LS, Linskey ME. Central causes of foot drop: rare and underappreciated differential diagnoses. J Spinal Cord Med. 2007;30(1):62–6.
7. Eskandary H, Hamzei A, Yasamy MT. Foot drop following brain lesion. Surg Neurol. 1995;43(1):89-90.
8. Jakubowitz E, Yao D, Windhagen H, Stukenborg-Colsman C, Thomann A, Daniilidis K. Treatment options for neurogenic foot drop: a systematic literature research. Z Orthop Unfall. 2017;155(4):402–8.
9. Ma J, He Y, Wang A, Wang W, Xi Y, Yu Y et al. Risk factors analysis for foot drop associated with lumbar disc herniation: an analysis of 236 patients. World Neurosurg. 2018;110:e1017-e1024. doi: 10.1016/j.wneu.2017.11.154.
10. van Zantvoort A, Setz M, Hoogeveen A, van Eerten P, Scheltinga M. Chronic lower leg pain: entrapment of common peroneal nerve or tibial nerve. Unfallchirurg. 2020;123(Suppl 1):20-24. doi: 10.1007/s00113-019-0645-5.
11. O'Brien M. Aids to the examination of the peripheral nervous system. Saunders Philadelphia, PA; 2010.
12. Oosterbos C, Decramer T, Rummens S, Weyns F, Dubuisson A, Ceuppens J et al. Evidence in peroneal nerve entrapment: A scoping review. Eur J Neurol. 2022;29(2):665-79.
13. Oosterbos C, Rasulic L, Rummens S, Kiekens C, van Loon J, Lemmens R et al. Controversies in treatment strategies in patients with foot drop due to peroneal nerve entrapment: Results of a survey among specialists. Brain Spine 2022; 2:100887. doi: 10.1016/j.bas.2022.100887.
14. Oosterbos C, Rummens S, Bogaerts K, Hoornaert S, Weyns F, Dubuisson A et al. Conservative versus surgical treatment of foot drop in peroneal nerve entrapment: rationale and design of a prospective, multi-centre, randomized parallel-group controlled trial. Trials 2022; 23(1):1065. doi: 10.1186/s13063-022-07009-x.
15. Aprile I, Tonali P, Caliandro P, Pazzaglia C, Foschini M, Di Stasio E, et al. Italian multicentre study of peroneal mononeuropathy: multiperspective follow-up. Neurol Sci. 2009;30(1):37–44.
16. Bai SX. Acupuncture for 24 cases of peroneal nerve palsy. World J Acupuncture - Moxibustion. 2012;22(3):55–6.
17. Kim DH, Kline DG. Management and results of peroneal nerve lesions. Neurosurgery. 1996;39(2):312-9.
18. Sipahioğlu S, Zehir S, Aşkar H, Işıkan UE. Peroneal nerve palsy secondary to prolonged squatting in seasonal farmworkers. Acta Orthop Traumatol Turc. 2015;49(1):45–50.
19. Tarabay B, Abdallah Y, Kobaiter-Maarrawi S, Yammine P, Maarrawi J. Outcome and prognosis of microsurgical decompression in idiopathic severe common fibular nerve entrapment: prospective clinical study. World Neurosurg. 2019;126:e281–e287. doi: 10.1016/j.wneu.2019.02.042.
20. George SC, Boyce DE. An evidence-based structured review to assess the results of common peroneal nerve repair. Plast Reconstr Surg. 2014;134(2):302e–311e. doi: 10.1097/PRS.0000000000000318.
21. Wilson C, Yaacoub AP, Bakare A, Bo N, Aasar A, Barbaro NM. Peroneal nerve decompression: institutional review and meta-analysis to identify prognostic associations with favorable and unfavorable surgical outcomes. J Neurosurg Spine. 2019;1-8. doi: 10.3171/2018.10.SPINE18626.
22. Emamhadi M, Bakhshayesh B, Andalib S. Surgical outcome of foot drop caused by common peroneal nerve injuries; is the glass half full or half empty? Acta Neurochir. 2016;158(6):1133–8.
23. Corriveau M, Lescher JD, Hanna AS. Peroneal nerve decompression. Neurosurg Focus. 2018;44:V6. doi: 10.3171/2018.1.FocusVid.17575.
24. Ducic I, Felder JM. Minimally invasive peripheral nerve surgery: peroneal nerve neurolysis. Microsurgery. 2012;32(1):26-30.
25. Kim DH, Murovic JA, Tiel RL, Kline DG. Management and outcomes in 318 operative common peroneal nerve lesions at the Louisiana State University Health Sciences Center. Neurosurgery. 2004;54(6):1421-8.
26. Cho D, Saetia K, Lee S, Kline DG, Kim DH. Peroneal nerve injury associated with sports-related knee injury. Neurosurg Focus. 2011;31(5):E11. doi: 10.3171/2011.9.FOCUS11187.
27. Nath RK, Lyons AB, Paizi M. Successful management of foot drop by nerve transfers to the deep peroneal nerve. J Reconstr Microsurg. 2008;24(6):419-27.
28. Krishnamurthy S, Ibrahim M. Tendon transfers in foot drop. Indian J Plast Surg. 2019; 52(1): 100-8.
29. Campbell WC, Crenshaw AH. Campbell's Operative Orthopaedics. 7th ed. St. Louis: The C.V. Mosby Company; 1987.
30. Salihagić, S, Hadziahmetović Z, Fazlić A. Classic and modified Barr's technique of anterior transfer of the tibialis posterior tendon in irreparable peroneal palsies. Bosn J Basic Med Sci. 2008;8(02):156-9.
31. Vigasio A, Marcoccio I, Patelli A, Mattiuzzo V, Prestini G. New tendon transfer for correction of drop-foot in common peroneal nerve palsy. Clin Orthop Relat Res. 2008;466(6):1454-66.
32. Divac N, Aksić M, Rasulić L, Jakovčevski M, Basailović M, Jakovčevski I. Pharmacology of repair after peripheral nerve injury. Int J Clin Pharmacol Ther. 2021;59(6):447-62.
33. Song SY, Nam DC, Moon DK, Lee DY, Lee EC, Kim DH. Surgical decompression timing for patients with foot drop from lumbar degenerative diseases: a meta-analysis. Eur Spine J. 2022;31(3):551-60.
34. Masuda S, Kanba Y, Kawai J, Ikeda N. Prognostic factors for drop foot due to lumbar degenerative diseases: The impact of surgical timing on postoperative recovery. Clin Spine Surg. 2020;33(4):160-2.
