The importance of microalbuminuria screening in persons with hypertension and with or without diabetes

  • Saška Severović doktor medicine
  • Gordana Bojić Institute for Occupational Health, Niš
  • Dragan Đorđević Institute for Workers' Health Protection Niš
Keywords: proteinuria, kidney diseases, risk assessment, biomarkers, early diagnosis

Abstract


 Introduction. Albumin is a protein produced in the
liver, playing a crucial role in maintaining osmotic pressure
and transporting molecules. Microalbuminuria, which is the
presence of small amounts of albumin in urine, often depicts
the damage to kidney function as well as the risk of developing
cardiovascular and cerebrovascular diseases.
Objective. We aimed to establish the prevalence of microalbuminuria
in patients with hypertension and diabetes,
and to estimate the prevalence in the difference between these
groups and the control group.
Method. The study encompassed 139 patients, separated
into the exposed group (patients with hypertension and
diabetes) and the control group. Microalbuminuria testing
was performed using qualitative test strips. These strips detect
albumin in urine. For statistical analysis, we used Chisquare
- χ2 test to evaluate the difference between the groups.
Results. The prevalence of microalbuminuria in the exposed
group was 33,09%. Statistically significant difference
in the prevalence of microalbuminuria between the exposed
and the control group was confirmed with p-values below
0,05. There were no significant differences in distribution according
to gender and age.
Conclusion. Microalbuminuria was registered in significant
percentages in patients with hypertension and diabetes,
which necessitates the need for regular screening in order
to timely detect changes in kidney function and calculate the
risk of cardiovascular diseases.

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Published
2025/10/06
How to Cite
Severović, S., Bojić, G., & Đorđević, D. (2025). The importance of microalbuminuria screening in persons with hypertension and with or without diabetes. General Practice, 31(3-4). https://doi.org/10.5937/opmed31-58027
Section
Original article