MAJOCCHI'S GRANULOMA OF THE VULVA – A CASE REPORT

  • Milan Bjekic City Institute for Skin and Venereal Diseases, Belgrade, Serbia
  • Danijela Pecarski Academy for Applied Studies Belgrade, Serbia
Keywords: Majocchi’s granuloma, vulva, Trichophyton rubrum, case report

Abstract


Introduction/Aim: Majocchi’s granuloma is an infrequent deep-seated fungal infection where pathogen invades hair follicles, entering the dermal and subcutaneous tissue, thus forming granulomatous dermal and/or hypodermal changes. There are two clinical types: the first one is common in healthy individuals characterized by superficial perifollicular papular infection, and the second is followed by the deep subcutaneous nodules usually reported among immunocompromised hosts. This infection is usually caused by Trichophyton rubrum. The aim of this paper is to show the rare localization of this disease in the area of the vulva.

Case report: We present a 20-year-old immunocompetent woman with multiple papules, nodules, and pustules on the hairy part of the vulva. Potassium hydroxide preparations of skin scrapings were negative and culture performed on Sabouraud glucose agar revealed Trichophyton rubrum. The patient was treated with the oral systemic antifungal therapy for four weeks and all lesions resolved.

Conclusion: Majocchi’s granuloma should not be overlooked in patients with papular and nodular lesions in the vulvar region.

References

Bjekic M, Vucinic M, Sipetic-Grujicic S. Epidemiological and clinical characteristics of dermatomycoses in children and adolescents. Health Care 2015; 44(2):10-16.

Ilkit M, Durdu M, Karakas M. Majocchi’s granuloma: a symptom complex caused by fungal pathogens. Med Mycol 2012; 50(5):449-57.

Chang SE, Lee DK, Choi JH, Moon KC, Koh JK. Majocchi’s granuloma of the vulva caused by Trichophyton mentagrophytes. Mycoses 2005; 48(6):382-4.

Gupta S, Kumar B, Radotre B , Rai R. Majocchi granuloma trichophyticum in an immunocompromised patient. Int J Dermatol 2000; 39(2):140-1.

Bjekic M, Gajica-Basara J. Majocchi’s granuloma in a healthy adult man – a case report. Serb J Dermatol Venereol 2015; 7(1): 34-40.

Published
2020/12/13
Section
Case report