CHRONIC PRESSURE ULCERS IN TRAUMA AND NON-TRAUMA PATIENTS IN THE INTENSIVE CARE UNIT

  • Milutin Mrvaljevic Department of Plastic Surgery, Urgent Care Center, University Clinical Center of Serbia, Belgrade, Republic of Serbia
  • Srbislav Pajic Department of Neurotraumatology, University Clincal Center of Serbia, Belgrade, Republic of Serbia
  • Drazen Radanovic Hospital for Neurosurgery, University Clinical Center of Serbia, Belgrade, Republic of Serbia
  • Nikola Slijepcevic Hospital for Endocrine Surgery, University Clinical Center of Serbia, Belgrade, Republic of Serbia; Faculty of Medicine, University of Belgrade, Republic of Serbia
  • Sofija Jakovljevic Urgent Care Center, University Clinical Center of Serbia, Belgrade, Republic of Serbia
  • Dusan Elboursh Urgent Care Center, University Clinical Center of Serbia, Belgrade, Republic of Serbia
  • Djurdjina Bogosavljevic Department of Physical Medicine and Rehabilitation, University Clinical Center of Serbia, Belgrade, Republic of Serbia
  • Bojan Cukic Department of Radiology, University Clinical Center of Serbia, Belgrade, Republic of Serbia
  • Milica Sumanac Department of Anaesthesiology, General Hospital Užice, Republic of Serbia
Keywords: : pressure ulcers, intensive care, chronic wounds, risk factors

Abstract


Introduction/Aim: Patients, who stay long in hospitals, nursing homes, and especially in intensive care units, are exposed to the risk of developing chronic wounds. The term “chronic wound” refers to wounds that do not heal despite all treatment measures taken in the period of six to eight weeks. The aim of this retrospective cohort study was to analyze data on chronic pressure ulcers that were collected in intensive care units (ICU) of the Urgent Care Center of the Clinical Center of Serbia during the five-year period, with the aim of determining the factors that influence their occurrence and healing.

Methods: The retrospective cohort study was conducted from January 1st, 2018 to April 1st, 2023 at the Urgent Care Center of the University Clinical Center of Serbia in the intensive care units in polytrauma, neurosurgical and surgical patients. The study included 74 patients diagnosed with chronic pressure ulcers. Data for all participants were obtained from medical history and a list of discharges.

Results: During in-hospital treatment in ICU, pressure ulcers were found in all 74 patients (56.8% of women and 43.2% of men), while combined chronic wounds were found in 57 (77.0%) patients. The largest number of these patients were elderly (70 and older) (31.1%) and with non-traumatic injuries (62%). All patients were tracheotomized with a gastrostomy tube placed. The localization of pressure ulcers was most often in the lumbosacral region (44.6%), followed by the trochanteric region (23.0%). The majority of patients had hypertension (90.5%), diabetes (79.7%), and chronic obstructive pulmonary disease (82.4%), while 28 patients (37.8%) died. 38 patients were underweight (51.4%), while 11 (14.9%) patients were overweight and obese.

Conclusion: Risk factors for the occurrence of pressure ulcers should be evaluated at the moment of the first contact of the doctor with the immobile patient because this is the only prerequisite for timely prevention. Special emphasis should be placed on the elderly, underweight, and people with comorbidities.

References

1. Lazarus GS, Cooper DM, Knighton DR, Percoraro RE, Rodeheaver G, Robson MC. Definitions and guidelines for assessment of wounds and evaluation of healing. Wound Repair Regen. 1994;2:165–70. doi:10.1001/ archderm.1994.01690040093015

2. Werdin F, Tennenhaus M, Schaller HE, Rennekampff HO. Evidencebased management strategies for treatment of chronic wounds. Eplasty. 2009;9:e19.

3. Mekkes JR, Loots MAM, Van Der Wal AC, Bos JD. Causes, investigation and treatment of leg ulceration. Br J Dermatol. 2003;148(3):388-401. doi: 10.1046/j.1365- 2133. 2003.05222

4. Cazander G, Pritchard DI, Nigam Y, Jung W, Nibbering PH. Multiple actions of Lucilia sericata larvae in hard‐to‐heal wounds. Bioessays. 2013;35(12):1083-92. doi:10.1002/ bies.201300071

5. The Wound Healing Society. Chronic wound care guidelines, 2006. Available at: http://woundheal. org/documents/final_pocket_guide_treatment.aspx (Accessed 20 Nov 2015)

6. Sen CK, Gordillo GM, Roy S, Kirsner R, Lambert L, Hunt TK, et al. Human skin wounds: a major and snowballing threat to public health and the economy. Wound Repair Regen. 2009;17(6):763-71. doi:10.1111/j.1524- 475X.2009.00543.x

7. Gottrup F. A specialized wound-healing center concept: importance of a multidisciplinary department structure and surgical treatment facilities in the treatment of chronic wounds. Am J Surg. 2004;187(5):S38–43. doi: 10.1016/S0002-9610(03)00303-9.

8. Wicke C, Bachinger A, Coerper S, Beckert S, Witte MB, Königsrainer A. Aging influences wound healing in patients with chronic lower extremity wounds treated in a specialized Wound Care Center. Wound Repair Regen. 2009;17(1):25-33. doi:10.1111/j.1524- 475X.2008.00438.x

9. Kloth L. The roles of physical therapists in wound management, part II: patient and wound evaluation. J Am Col Certif Wound Spec. 2009;1(2):49-50. doi: 10.1016/j. jcws.2009.03.003

10. Cox J. Pressure injury risk factors in adult critical care patients: a review of the literature. Ostomy Wound Manag. 2017;63:30–43.

11. Coyer F, Miles S, Gosley S et al. Pressure injury prevalence in intensive care versus non-intensive care patients: a state-wide comparison. Aust Crit Care. 2017;30:244–50. doi: 10.1016/j.aucc.2016.12.003.

12. Soodmand M, Moghadamnia MT, Aghaei I, Ghasemzadeh G, Lili EK, Rad EH. Effects of hemodynamic factors and oxygenation on the incidence of pressure ulcers in the ICU. Adv Skin Wound Care. 2019;32:359–64. doi: 10.1097/01.ASW.0000553599.20444.f4.

13. Barakat-Johnson M, Lai M, Wand T, Li MB, White K, Coyer F. The incidence and prevalence of medical device-related pressure ulcers in intensive care: a systematic review. J Wound Care. 2019;28:512–21. doi: 10.12968/jowc.2019.28.8.512.

14. Kahn JM, Le T, Angus DC, Cox CE, Hough CL, White DB, Yende S, et al. The epidemiology of chronic critical illness in the United States. Crit Care Med. 2015;43(2):282–7. doi: 10.1097/CCM.0000000000000710.

15. Flaatten H, de Lange DW, Artigas A, Bin D, Moreno R, Christensen S, et al. The status of intensive care medicine research and a future agenda for very old patients in the ICU. Intensive Care Med. 2017;43:1319–28. doi: 10.1007/ s00134-017-4718-z.

16. Laporte L, Hermetet C, Jouan Y, Gaborit C, Rouve E, Shea KM, et al. Ten-year trends in intensive care admissions for respiratory infections in the elderly. Ann Intensive Care. 2018;8(1):84. doi: 10.1186/s13613-018-0430-6.

17. Leaper DJ, Schultz G, Carville K, et al. Extending the TIME concept: what have we learned in the past 10 years? Int Wound J. 2012;9(suppl 2):1-19. doi: 10.1111/j.1742- 481X.2012.01097.x.

18. Krause T, Anders J, Heinemann A, Cordes O, Wilke L, Kranz S, Kühlet M. Ursachenzusammenhänge der Dekubitusentstehung. Ergebnisse einer Fall-KontrollStudie mit 200 Patienten und Befragung aller an der Pflege Beteiligten. Kohlhammer: Stuttgart; 2004.

19. Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract. 2010;87:4–14. doi: 10.1016/j. diabres.2009.10.007

20. Singh N, Armstrong DG, Lipsky BA. Preventing foot ulcers in patients with diabetes. JAMA. 2005;293:217–28. doi: 10.1001/jama.293.2.217.

21. WHO Guideline Development Committee. Definition and Diagnosis of Diabetes Mellitus and Intermediate Hyperglycaemia. Report of a WHO/IDF Consultation: Geneve; 2006.

22. Jebakumar AJ, Udayakumar PD, Crowson CS, Gabriel SE, Matteson EL. Occurrence and effect of lower extremity ulcer in rheumatoid arthritis -- a population-based Study. J Rheumatol. 2014;41(3):437-43. doi: 10.3899/ jrheum.130392.

23. Tillmann M. Zur Situation der Senioren in Hamburg und Umland - Ergebnisse einer rechtsmedizinischen Studie anlässlich der Krematoriumsleichenschau 2008 am Beispiel von Decubitalulcera. Medizinische Dissertation. Institut für Rechtsmedizin der Universität Hamburg: Hamburg; 2010.

24. Workum JD, van Olffen A, Vaes PJ, van Gestel A, Vos P, Ramnarain D. The association between obesity and pressure ulcer development in critically ill patients: A prospective cohort study. Obes Res Clin Pract. 2022;16(1):56-62. doi:10.1016/j.orcp.2022.01.003

25. Fentahun N, Anteneh Y, Menber Y. Malnutrition in the Outcome of Wound Healing at Public Hospitals in Bahir Dar City, Northwest Ethiopia: A Prospective Cohort Study. J Nutr Metab. 2021;2021:8824951. doi: 10.1155/2021/8824951

Published
2023/07/04
Section
ORIGINAL ARTICLE